Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica

Background: Surgery is an effective method for the management of renal hyperparathyroidism. Aim: To report the clinical presentation and results of surgical treatment of renal hyperparathyroidism. Material and Methods: Retrospective analysis of 58 patients aged 46 ± 11 years with secondary hyperpara...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pulgar B,Dahiana, Jara C,Aquiles, González V,Gilberto, González D,Hernán
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Hyperparathyroidism, secondary Parathyroid hormone Surgery
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000200006
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872015000200006
record_format	dspace
spelling	oai:scielo:S0034-988720150002000062015-04-09Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónicaPulgar B,DahianaJara C,AquilesGonzález V,GilbertoGonzález D,Hernán Hyperparathyroidism, secondary Parathyroid hormone Surgery Background: Surgery is an effective method for the management of renal hyperparathyroidism. Aim: To report the clinical presentation and results of surgical treatment of renal hyperparathyroidism. Material and Methods: Retrospective analysis of 58 patients aged 46 ± 11 years with secondary hyperparathyroidism (HPT2) and 13 patients aged 53 ± 11 years with tertiary hyperparathyroidism (HPT3), operated at a clinical hospital. Results: In 55 cases (77.4%) the indications for surgery were complications of excess parathyroid hormone (PTH) and in 16 patients (22.6%) a failure of medical treatment. Total parathyroidectomy with intraoperative measurement of PTH (PTHop) plus a forearm parathyroid autograft was performed in 54 (93.1%) patients with HPT2 and in all patients with HPT3. PTHop decreased ≥ 75% in 51 patients (88%) with HPT2 and in 9 patients (69.2%) with HPT3, respectively. Cure of the disease was achieved in 52 (89.7%) and 11 (84.6%) patients with HPT2 and 3, respectively. Median follow-up was 41 months. Five (9.6%) patients with HPT2 and two patients (18.2%) with HPT3 had a recurrence of the disease. Conclusions: In patients with renal hyperparathyroidism, the primary indication for surgery was the presence of complications of PTH excess. A drop in PTHop ≥ 75% from baseline predicts healing in 98% and 100% of cases with secondary or tertiary HPT respectively. Surgery was a safe and effective treatment in both groups.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.2 20152015-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000200006es10.4067/S0034-98872015000200006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hyperparathyroidism, secondary Parathyroid hormone Surgery
spellingShingle	Hyperparathyroidism, secondary Parathyroid hormone Surgery Pulgar B,Dahiana Jara C,Aquiles González V,Gilberto González D,Hernán Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
description	Background: Surgery is an effective method for the management of renal hyperparathyroidism. Aim: To report the clinical presentation and results of surgical treatment of renal hyperparathyroidism. Material and Methods: Retrospective analysis of 58 patients aged 46 ± 11 years with secondary hyperparathyroidism (HPT2) and 13 patients aged 53 ± 11 years with tertiary hyperparathyroidism (HPT3), operated at a clinical hospital. Results: In 55 cases (77.4%) the indications for surgery were complications of excess parathyroid hormone (PTH) and in 16 patients (22.6%) a failure of medical treatment. Total parathyroidectomy with intraoperative measurement of PTH (PTHop) plus a forearm parathyroid autograft was performed in 54 (93.1%) patients with HPT2 and in all patients with HPT3. PTHop decreased ≥ 75% in 51 patients (88%) with HPT2 and in 9 patients (69.2%) with HPT3, respectively. Cure of the disease was achieved in 52 (89.7%) and 11 (84.6%) patients with HPT2 and 3, respectively. Median follow-up was 41 months. Five (9.6%) patients with HPT2 and two patients (18.2%) with HPT3 had a recurrence of the disease. Conclusions: In patients with renal hyperparathyroidism, the primary indication for surgery was the presence of complications of PTH excess. A drop in PTHop ≥ 75% from baseline predicts healing in 98% and 100% of cases with secondary or tertiary HPT respectively. Surgery was a safe and effective treatment in both groups.
author	Pulgar B,Dahiana Jara C,Aquiles González V,Gilberto González D,Hernán
author_facet	Pulgar B,Dahiana Jara C,Aquiles González V,Gilberto González D,Hernán
author_sort	Pulgar B,Dahiana
title	Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
title_short	Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
title_full	Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
title_fullStr	Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
title_full_unstemmed	Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
title_sort	tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000200006
work_keys_str_mv	AT pulgarbdahiana tratamientoquirurgicodelhiperparatiroidismoasociadoainsuficienciarenalcronica AT jaracaquiles tratamientoquirurgicodelhiperparatiroidismoasociadoainsuficienciarenalcronica AT gonzalezvgilberto tratamientoquirurgicodelhiperparatiroidismoasociadoainsuficienciarenalcronica AT gonzalezdhernan tratamientoquirurgicodelhiperparatiroidismoasociadoainsuficienciarenalcronica
_version_	1718436804232740864

Tratamiento quirúrgico del hiperparatiroidismo asociado a insuficiencia renal crónica

Ejemplares similares