Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos

Background: DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction. Aim: To report the etiology, characteristics, treatment, prognosis, and fol...

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Autores principales:	Ocampo-Garza,Jorge, Ocampo-Garza,Sonia Sofía, Martínez-Villarreal,José Darío, Barbosa-Moreno,Laura Elena, Guerrero-González,Guillermo Antonio, Ocampo-Candiani,Jorge
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Dexamethasone Drug eruptions Drug hypersensitivity syndrome
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500004
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spelling	oai:scielo:S0034-988720150005000042018-10-31Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casosOcampo-Garza,JorgeOcampo-Garza,Sonia SofíaMartínez-Villarreal,José DaríoBarbosa-Moreno,Laura ElenaGuerrero-González,Guillermo AntonioOcampo-Candiani,Jorge Dexamethasone Drug eruptions Drug hypersensitivity syndrome Background: DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction. Aim: To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material and Methods: Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease. Results: Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution. Conclusions: DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.5 20152015-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500004es10.4067/S0034-98872015000500004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Dexamethasone Drug eruptions Drug hypersensitivity syndrome
spellingShingle	Dexamethasone Drug eruptions Drug hypersensitivity syndrome Ocampo-Garza,Jorge Ocampo-Garza,Sonia Sofía Martínez-Villarreal,José Darío Barbosa-Moreno,Laura Elena Guerrero-González,Guillermo Antonio Ocampo-Candiani,Jorge Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos
description	Background: DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction. Aim: To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material and Methods: Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease. Results: Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution. Conclusions: DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.
author	Ocampo-Garza,Jorge Ocampo-Garza,Sonia Sofía Martínez-Villarreal,José Darío Barbosa-Moreno,Laura Elena Guerrero-González,Guillermo Antonio Ocampo-Candiani,Jorge
author_facet	Ocampo-Garza,Jorge Ocampo-Garza,Sonia Sofía Martínez-Villarreal,José Darío Barbosa-Moreno,Laura Elena Guerrero-González,Guillermo Antonio Ocampo-Candiani,Jorge
author_sort	Ocampo-Garza,Jorge
title	Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos
title_short	Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos
title_full	Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos
title_fullStr	Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos
title_full_unstemmed	Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos
title_sort	reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de dress): estudio retrospectivo de nueve casos
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500004
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Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos

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