Sensibilidad no celíaca al gluten: Una patología más que responde al gluten

Remission of gastrointestinal and general symptoms after gluten withdrawal has been described in some non-celiac individuals for nearly 30 years. Only recently, efforts have been made to define this entity, now referred to as "non- celiac gluten sensitivity". It includes patients that clin...

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Autores principales:	Navarro,Elizabeth, Araya,Magdalena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Celiac disease FODMAPs Irritable bowel syndrome Non-celiac gluten sensitivity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500010
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spelling	oai:scielo:S0034-988720150005000102018-10-31Sensibilidad no celíaca al gluten: Una patología más que responde al glutenNavarro,ElizabethAraya,Magdalena Celiac disease FODMAPs Irritable bowel syndrome Non-celiac gluten sensitivity Remission of gastrointestinal and general symptoms after gluten withdrawal has been described in some non-celiac individuals for nearly 30 years. Only recently, efforts have been made to define this entity, now referred to as "non- celiac gluten sensitivity". It includes patients that clinically respond to gluten free diet without exhibiting allergic or autoimmune features to explain such response. Wheat allergy, celiac disease, irritable bowel syndrome and symptoms induced by high FODMAPs (Fermentable, Oligo-, Di-, Mono-saccharides And Polyols) consumption are the main differential diagnoses. The relationship with neuropsychiatric disorders such as schizophrenia and autism has not been demonstrated, but currently it gives ground to great hope in families with affected children. Epidemiology of non-celiac gluten sensitivity is not clear. It is described as more common among women and less common in children. Genetic and immune factors, changes in intestinal microbiota and non-gluten components present in wheat grains are main factors postulated in the pathogenesis of this condition. To date, there are no specific biomarkers for non-celiac gluten sensitivity and diagnosis is reached by excluding other causes of disease. A trial with gluten-free diet and subsequent gluten challenge is the methodology most frequently used to confirm diagnosis.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.5 20152015-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500010es10.4067/S0034-98872015000500010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Celiac disease FODMAPs Irritable bowel syndrome Non-celiac gluten sensitivity
spellingShingle	Celiac disease FODMAPs Irritable bowel syndrome Non-celiac gluten sensitivity Navarro,Elizabeth Araya,Magdalena Sensibilidad no celíaca al gluten: Una patología más que responde al gluten
description	Remission of gastrointestinal and general symptoms after gluten withdrawal has been described in some non-celiac individuals for nearly 30 years. Only recently, efforts have been made to define this entity, now referred to as "non- celiac gluten sensitivity". It includes patients that clinically respond to gluten free diet without exhibiting allergic or autoimmune features to explain such response. Wheat allergy, celiac disease, irritable bowel syndrome and symptoms induced by high FODMAPs (Fermentable, Oligo-, Di-, Mono-saccharides And Polyols) consumption are the main differential diagnoses. The relationship with neuropsychiatric disorders such as schizophrenia and autism has not been demonstrated, but currently it gives ground to great hope in families with affected children. Epidemiology of non-celiac gluten sensitivity is not clear. It is described as more common among women and less common in children. Genetic and immune factors, changes in intestinal microbiota and non-gluten components present in wheat grains are main factors postulated in the pathogenesis of this condition. To date, there are no specific biomarkers for non-celiac gluten sensitivity and diagnosis is reached by excluding other causes of disease. A trial with gluten-free diet and subsequent gluten challenge is the methodology most frequently used to confirm diagnosis.
author	Navarro,Elizabeth Araya,Magdalena
author_facet	Navarro,Elizabeth Araya,Magdalena
author_sort	Navarro,Elizabeth
title	Sensibilidad no celíaca al gluten: Una patología más que responde al gluten
title_short	Sensibilidad no celíaca al gluten: Una patología más que responde al gluten
title_full	Sensibilidad no celíaca al gluten: Una patología más que responde al gluten
title_fullStr	Sensibilidad no celíaca al gluten: Una patología más que responde al gluten
title_full_unstemmed	Sensibilidad no celíaca al gluten: Una patología más que responde al gluten
title_sort	sensibilidad no celíaca al gluten: una patología más que responde al gluten
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500010
work_keys_str_mv	AT navarroelizabeth sensibilidadnoceliacaalglutenunapatologiamasquerespondealgluten AT arayamagdalena sensibilidadnoceliacaalglutenunapatologiamasquerespondealgluten
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Sensibilidad no celíaca al gluten: Una patología más que responde al gluten

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