Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associate...
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Sociedad Médica de Santiago
2015
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oai:scielo:S0034-988720150005000112018-10-31Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazoSepulveda-Martinez,AlvaroRomero,CarlosJuarez,GuidoHasbun,JorgeParra-Cordero,Mauro Acetaminophen Fatty liver HELLP Liver failure Pregnancy complications Syndrome Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.5 20152015-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500011es10.4067/S0034-98872015000500011 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Acetaminophen Fatty liver HELLP Liver failure Pregnancy complications Syndrome |
spellingShingle |
Acetaminophen Fatty liver HELLP Liver failure Pregnancy complications Syndrome Sepulveda-Martinez,Alvaro Romero,Carlos Juarez,Guido Hasbun,Jorge Parra-Cordero,Mauro Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
description |
Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial. |
author |
Sepulveda-Martinez,Alvaro Romero,Carlos Juarez,Guido Hasbun,Jorge Parra-Cordero,Mauro |
author_facet |
Sepulveda-Martinez,Alvaro Romero,Carlos Juarez,Guido Hasbun,Jorge Parra-Cordero,Mauro |
author_sort |
Sepulveda-Martinez,Alvaro |
title |
Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
title_short |
Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
title_full |
Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
title_fullStr |
Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
title_full_unstemmed |
Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
title_sort |
actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo |
publisher |
Sociedad Médica de Santiago |
publishDate |
2015 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500011 |
work_keys_str_mv |
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