Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo

Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associate...

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Autores principales: Sepulveda-Martinez,Alvaro, Romero,Carlos, Juarez,Guido, Hasbun,Jorge, Parra-Cordero,Mauro
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2015
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500011
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spelling oai:scielo:S0034-988720150005000112018-10-31Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazoSepulveda-Martinez,AlvaroRomero,CarlosJuarez,GuidoHasbun,JorgeParra-Cordero,Mauro Acetaminophen Fatty liver HELLP Liver failure Pregnancy complications Syndrome Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.5 20152015-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500011es10.4067/S0034-98872015000500011
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Acetaminophen
Fatty liver
HELLP
Liver failure
Pregnancy complications
Syndrome
spellingShingle Acetaminophen
Fatty liver
HELLP
Liver failure
Pregnancy complications
Syndrome
Sepulveda-Martinez,Alvaro
Romero,Carlos
Juarez,Guido
Hasbun,Jorge
Parra-Cordero,Mauro
Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
description Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial.
author Sepulveda-Martinez,Alvaro
Romero,Carlos
Juarez,Guido
Hasbun,Jorge
Parra-Cordero,Mauro
author_facet Sepulveda-Martinez,Alvaro
Romero,Carlos
Juarez,Guido
Hasbun,Jorge
Parra-Cordero,Mauro
author_sort Sepulveda-Martinez,Alvaro
title Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
title_short Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
title_full Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
title_fullStr Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
title_full_unstemmed Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
title_sort actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo
publisher Sociedad Médica de Santiago
publishDate 2015
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000500011
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