Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos

Background: Plasma ghrelin levels may decrease after vertical sleeve gastrectomy, probably due to the excision of a large portion of the gastric fundus. It is worth exploring the long term effects of this surgical procedure on ghrelin levels and their associations with changes in body weight. Aim: T...

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Autores principales: Braghetto,Italo, Taladriz,Cristian, Lanzarini,Enrique, Romero,Carmen
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2015
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000700006
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spelling oai:scielo:S0034-988720150007000062015-09-03Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesosBraghetto,ItaloTaladriz,CristianLanzarini,EnriqueRomero,Carmen Body mass index Follow-up studies Gastrectomy Ghrelin Laparoscopy Background: Plasma ghrelin levels may decrease after vertical sleeve gastrectomy, probably due to the excision of a large portion of the gastric fundus. It is worth exploring the long term effects of this surgical procedure on ghrelin levels and their associations with changes in body weight. Aim: To assess ghrelin levels and changes in body weight, one and five years after a vertical sleeve gastrectomy. Material and Methods: Plasma ghrelin was measured prior to gastric sleeve gastrectomy, immediately after surgery and BMI was controlled at one and five years of the postoperative period in 16 and 10 obese patients, respectively. Mean baseline body mass index was 40.4 ± 6 kg/m². Results: Ghrelin decreased in 10 patients and increased in six during the long term postoperative period. At one year, mean body mass index decreased to 25.1 ± 1.6 kg/m². Changes in weight and ghrelin levels had no relationship whatsoever. At five years of follow up, body mass index had increased to 29.9 ± 2.5 kg/m², again without any association with ghrelin levels. Conclusions: Ghrelin levels may decrease or increase after vertical sleeve gastrectomy and have no association with changes in body weight.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.7 20152015-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000700006es10.4067/S0034-98872015000700006
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Body mass index
Follow-up studies
Gastrectomy
Ghrelin
Laparoscopy
spellingShingle Body mass index
Follow-up studies
Gastrectomy
Ghrelin
Laparoscopy
Braghetto,Italo
Taladriz,Cristian
Lanzarini,Enrique
Romero,Carmen
Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
description Background: Plasma ghrelin levels may decrease after vertical sleeve gastrectomy, probably due to the excision of a large portion of the gastric fundus. It is worth exploring the long term effects of this surgical procedure on ghrelin levels and their associations with changes in body weight. Aim: To assess ghrelin levels and changes in body weight, one and five years after a vertical sleeve gastrectomy. Material and Methods: Plasma ghrelin was measured prior to gastric sleeve gastrectomy, immediately after surgery and BMI was controlled at one and five years of the postoperative period in 16 and 10 obese patients, respectively. Mean baseline body mass index was 40.4 ± 6 kg/m². Results: Ghrelin decreased in 10 patients and increased in six during the long term postoperative period. At one year, mean body mass index decreased to 25.1 ± 1.6 kg/m². Changes in weight and ghrelin levels had no relationship whatsoever. At five years of follow up, body mass index had increased to 29.9 ± 2.5 kg/m², again without any association with ghrelin levels. Conclusions: Ghrelin levels may decrease or increase after vertical sleeve gastrectomy and have no association with changes in body weight.
author Braghetto,Italo
Taladriz,Cristian
Lanzarini,Enrique
Romero,Carmen
author_facet Braghetto,Italo
Taladriz,Cristian
Lanzarini,Enrique
Romero,Carmen
author_sort Braghetto,Italo
title Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
title_short Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
title_full Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
title_fullStr Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
title_full_unstemmed Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
title_sort efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
publisher Sociedad Médica de Santiago
publishDate 2015
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000700006
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AT taladrizcristian efectodelagastrectomiatubularverticalenlosnivelesdeghrelinaplasmaticaenpacientesobesos
AT lanzarinienrique efectodelagastrectomiatubularverticalenlosnivelesdeghrelinaplasmaticaenpacientesobesos
AT romerocarmen efectodelagastrectomiatubularverticalenlosnivelesdeghrelinaplasmaticaenpacientesobesos
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