Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos
Background: Plasma ghrelin levels may decrease after vertical sleeve gastrectomy, probably due to the excision of a large portion of the gastric fundus. It is worth exploring the long term effects of this surgical procedure on ghrelin levels and their associations with changes in body weight. Aim: T...
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Sociedad Médica de Santiago
2015
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oai:scielo:S0034-988720150007000062015-09-03Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesosBraghetto,ItaloTaladriz,CristianLanzarini,EnriqueRomero,Carmen Body mass index Follow-up studies Gastrectomy Ghrelin Laparoscopy Background: Plasma ghrelin levels may decrease after vertical sleeve gastrectomy, probably due to the excision of a large portion of the gastric fundus. It is worth exploring the long term effects of this surgical procedure on ghrelin levels and their associations with changes in body weight. Aim: To assess ghrelin levels and changes in body weight, one and five years after a vertical sleeve gastrectomy. Material and Methods: Plasma ghrelin was measured prior to gastric sleeve gastrectomy, immediately after surgery and BMI was controlled at one and five years of the postoperative period in 16 and 10 obese patients, respectively. Mean baseline body mass index was 40.4 ± 6 kg/m². Results: Ghrelin decreased in 10 patients and increased in six during the long term postoperative period. At one year, mean body mass index decreased to 25.1 ± 1.6 kg/m². Changes in weight and ghrelin levels had no relationship whatsoever. At five years of follow up, body mass index had increased to 29.9 ± 2.5 kg/m², again without any association with ghrelin levels. Conclusions: Ghrelin levels may decrease or increase after vertical sleeve gastrectomy and have no association with changes in body weight.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.7 20152015-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000700006es10.4067/S0034-98872015000700006 |
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Scielo Chile |
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Scielo Chile |
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Spanish / Castilian |
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Body mass index Follow-up studies Gastrectomy Ghrelin Laparoscopy |
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Body mass index Follow-up studies Gastrectomy Ghrelin Laparoscopy Braghetto,Italo Taladriz,Cristian Lanzarini,Enrique Romero,Carmen Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
description |
Background: Plasma ghrelin levels may decrease after vertical sleeve gastrectomy, probably due to the excision of a large portion of the gastric fundus. It is worth exploring the long term effects of this surgical procedure on ghrelin levels and their associations with changes in body weight. Aim: To assess ghrelin levels and changes in body weight, one and five years after a vertical sleeve gastrectomy. Material and Methods: Plasma ghrelin was measured prior to gastric sleeve gastrectomy, immediately after surgery and BMI was controlled at one and five years of the postoperative period in 16 and 10 obese patients, respectively. Mean baseline body mass index was 40.4 ± 6 kg/m². Results: Ghrelin decreased in 10 patients and increased in six during the long term postoperative period. At one year, mean body mass index decreased to 25.1 ± 1.6 kg/m². Changes in weight and ghrelin levels had no relationship whatsoever. At five years of follow up, body mass index had increased to 29.9 ± 2.5 kg/m², again without any association with ghrelin levels. Conclusions: Ghrelin levels may decrease or increase after vertical sleeve gastrectomy and have no association with changes in body weight. |
author |
Braghetto,Italo Taladriz,Cristian Lanzarini,Enrique Romero,Carmen |
author_facet |
Braghetto,Italo Taladriz,Cristian Lanzarini,Enrique Romero,Carmen |
author_sort |
Braghetto,Italo |
title |
Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
title_short |
Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
title_full |
Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
title_fullStr |
Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
title_full_unstemmed |
Efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
title_sort |
efecto de la gastrectomía tubular vertical en los niveles de ghrelina plasmática en pacientes obesos |
publisher |
Sociedad Médica de Santiago |
publishDate |
2015 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000700006 |
work_keys_str_mv |
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