Orbitopatía de Graves en pediatría

Graves orbitopathy (GO) is rare in pediatric patients, however is the most common extrathyroid manifestation of Graves disease (GD), being present in 30-67% of patients. GO is an autoimmune inflammatory disorder involving orbital connective and fatty tissues as well as the extraocular muscles. In...

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Autores principales:	Mendoza F,Carolina, Lacourt R,Patricia
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Child Graves disease Graves ophthalmopathy Glucocorticoids
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000800011
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spelling	oai:scielo:S0034-988720150008000112015-10-01Orbitopatía de Graves en pediatríaMendoza F,CarolinaLacourt R,Patricia Child Graves disease Graves ophthalmopathy Glucocorticoids Graves orbitopathy (GO) is rare in pediatric patients, however is the most common extrathyroid manifestation of Graves disease (GD), being present in 30-67% of patients. GO is an autoimmune inflammatory disorder involving orbital connective and fatty tissues as well as the extraocular muscles. In children, GO is less common and less severe than in adults. The most common symptoms are upper eyelid retraction, conjunctival injection, and proptosis and periorbital edema. Severe complications include dysthyroid optic neuropathy, corneal ulceration and eyeball subluxation. The diagnosis is established by clinical, laboratory and imaging findings. There are no management guidelines for GO in children but adult recommendations include the assessment of clinical activity and its severity, to implement the best treatment. Supportive therapies are intended to relieve symptoms and prevent corneal damage in mild cases. Tobacco exposure should also be avoided. The first line of treatment is systemic administration of corticosteroids in active and severe cases. Other options as somatostatin use and retrobulbar radiation have not been used in children, therefore their use is not recommended.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.8 20152015-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000800011es10.4067/S0034-98872015000800011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Child Graves disease Graves ophthalmopathy Glucocorticoids
spellingShingle	Child Graves disease Graves ophthalmopathy Glucocorticoids Mendoza F,Carolina Lacourt R,Patricia Orbitopatía de Graves en pediatría
description	Graves orbitopathy (GO) is rare in pediatric patients, however is the most common extrathyroid manifestation of Graves disease (GD), being present in 30-67% of patients. GO is an autoimmune inflammatory disorder involving orbital connective and fatty tissues as well as the extraocular muscles. In children, GO is less common and less severe than in adults. The most common symptoms are upper eyelid retraction, conjunctival injection, and proptosis and periorbital edema. Severe complications include dysthyroid optic neuropathy, corneal ulceration and eyeball subluxation. The diagnosis is established by clinical, laboratory and imaging findings. There are no management guidelines for GO in children but adult recommendations include the assessment of clinical activity and its severity, to implement the best treatment. Supportive therapies are intended to relieve symptoms and prevent corneal damage in mild cases. Tobacco exposure should also be avoided. The first line of treatment is systemic administration of corticosteroids in active and severe cases. Other options as somatostatin use and retrobulbar radiation have not been used in children, therefore their use is not recommended.
author	Mendoza F,Carolina Lacourt R,Patricia
author_facet	Mendoza F,Carolina Lacourt R,Patricia
author_sort	Mendoza F,Carolina
title	Orbitopatía de Graves en pediatría
title_short	Orbitopatía de Graves en pediatría
title_full	Orbitopatía de Graves en pediatría
title_fullStr	Orbitopatía de Graves en pediatría
title_full_unstemmed	Orbitopatía de Graves en pediatría
title_sort	orbitopatía de graves en pediatría
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000800011
work_keys_str_mv	AT mendozafcarolina orbitopatiadegravesenpediatria AT lacourtrpatricia orbitopatiadegravesenpediatria
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Orbitopatía de Graves en pediatría

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