Linfoma intravascular, un desafio diagnóstico: Caso clínico

Intravascular lymphoma is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by clonal proliferation of lymphocytes inside of small and medium caliber vessels. Its incidence is estimated at one case per million. The clinical picture is very variable, but frequently has skin and...

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Autores principales:	Young,Pablo, Massa,María, Finn,Bárbara C, Fleire,Gonzalo, Stemmelin,Germán R, Ruades,Amanda, Sutovsky,Daniel, Casas,José G, Dezanzo,Pablo, Vigovich,Félix, Bruetman,Julio E
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Hematopoietic stem cell transplantation Lymphoma, B-cell Rituximab
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000800017
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spelling	oai:scielo:S0034-988720150008000172015-10-01Linfoma intravascular, un desafio diagnóstico: Caso clínicoYoung,PabloMassa,MaríaFinn,Bárbara CFleire,GonzaloStemmelin,Germán RRuades,AmandaSutovsky,DanielCasas,José GDezanzo,PabloVigovich,FélixBruetman,Julio E Hematopoietic stem cell transplantation Lymphoma, B-cell Rituximab Intravascular lymphoma is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by clonal proliferation of lymphocytes inside of small and medium caliber vessels. Its incidence is estimated at one case per million. The clinical picture is very variable, but frequently has skin and central nervous system involvement. It is diagnosed by demonstrating pathological blood vessel infiltration by lymphoma cells. We report a 44 years old male presenting with fever, malaise and erythematous lesions in the abdominal wall. An abdominal wall biopsy showed dilated vascular vessels with atypical cells in their lumen, compatible with large B-cell intravascular lymphoma. He was treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone and an autologous hematopoietic stem cell transplantation, achieving a complete remission that has lasted two years.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.8 20152015-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000800017es10.4067/S0034-98872015000800017
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hematopoietic stem cell transplantation Lymphoma, B-cell Rituximab
spellingShingle	Hematopoietic stem cell transplantation Lymphoma, B-cell Rituximab Young,Pablo Massa,María Finn,Bárbara C Fleire,Gonzalo Stemmelin,Germán R Ruades,Amanda Sutovsky,Daniel Casas,José G Dezanzo,Pablo Vigovich,Félix Bruetman,Julio E Linfoma intravascular, un desafio diagnóstico: Caso clínico
description	Intravascular lymphoma is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by clonal proliferation of lymphocytes inside of small and medium caliber vessels. Its incidence is estimated at one case per million. The clinical picture is very variable, but frequently has skin and central nervous system involvement. It is diagnosed by demonstrating pathological blood vessel infiltration by lymphoma cells. We report a 44 years old male presenting with fever, malaise and erythematous lesions in the abdominal wall. An abdominal wall biopsy showed dilated vascular vessels with atypical cells in their lumen, compatible with large B-cell intravascular lymphoma. He was treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone and an autologous hematopoietic stem cell transplantation, achieving a complete remission that has lasted two years.
author	Young,Pablo Massa,María Finn,Bárbara C Fleire,Gonzalo Stemmelin,Germán R Ruades,Amanda Sutovsky,Daniel Casas,José G Dezanzo,Pablo Vigovich,Félix Bruetman,Julio E
author_facet	Young,Pablo Massa,María Finn,Bárbara C Fleire,Gonzalo Stemmelin,Germán R Ruades,Amanda Sutovsky,Daniel Casas,José G Dezanzo,Pablo Vigovich,Félix Bruetman,Julio E
author_sort	Young,Pablo
title	Linfoma intravascular, un desafio diagnóstico: Caso clínico
title_short	Linfoma intravascular, un desafio diagnóstico: Caso clínico
title_full	Linfoma intravascular, un desafio diagnóstico: Caso clínico
title_fullStr	Linfoma intravascular, un desafio diagnóstico: Caso clínico
title_full_unstemmed	Linfoma intravascular, un desafio diagnóstico: Caso clínico
title_sort	linfoma intravascular, un desafio diagnóstico: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000800017
work_keys_str_mv	AT youngpablo linfomaintravascularundesafiodiagnosticocasoclinico AT massamaria linfomaintravascularundesafiodiagnosticocasoclinico AT finnbarbarac linfomaintravascularundesafiodiagnosticocasoclinico AT fleiregonzalo linfomaintravascularundesafiodiagnosticocasoclinico AT stemmelingermanr linfomaintravascularundesafiodiagnosticocasoclinico AT ruadesamanda linfomaintravascularundesafiodiagnosticocasoclinico AT sutovskydaniel linfomaintravascularundesafiodiagnosticocasoclinico AT casasjoseg linfomaintravascularundesafiodiagnosticocasoclinico AT dezanzopablo linfomaintravascularundesafiodiagnosticocasoclinico AT vigovichfelix linfomaintravascularundesafiodiagnosticocasoclinico AT bruetmanjulioe linfomaintravascularundesafiodiagnosticocasoclinico
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Linfoma intravascular, un desafio diagnóstico: Caso clínico

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