Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso

Background: Heart rate variability analysis provides quantitative information about vagal and sympathetic modulation of cardiac function. Aim: To analyze the relationship between heart rate variability and insulin resistance in obese patients. Material and Methods: Male participants were studied, di...

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Autores principales:	Espinoza-Salinas,Alexis, Zafra-Santos,Edson, Pavez-Von Martens,Gustavo, Cofré-Bolados,Cristian, Lemus-Zúñiga,Jorge, Sánchez-Aguilera,Pablo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Autonomic nervous system Heart rate Insulin resistance Obesity Overweight
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000900005
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spelling	oai:scielo:S0034-988720150009000052015-10-22Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepesoEspinoza-Salinas,AlexisZafra-Santos,EdsonPavez-Von Martens,GustavoCofré-Bolados,CristianLemus-Zúñiga,JorgeSánchez-Aguilera,Pablo Autonomic nervous system Heart rate Insulin resistance Obesity Overweight Background: Heart rate variability analysis provides quantitative information about vagal and sympathetic modulation of cardiac function. Aim: To analyze the relationship between heart rate variability and insulin resistance in obese patients. Material and Methods: Male participants were studied, divided in 10 obese subjects aged 27 ± 2 years with a body mass index (BMI) of 31.2 ± 1.3 kg/m², 15 overweight subjects aged 24 ± 3 years with a BMI of 26.7 ± 1.5 kg/m² and 14 normal weight subjects aged 21 ± 2 years with a BMI of 22.5 ± 1.3 kg/m². Resting heart rate variability was measured in a period of 5 minutes. A spectral analysis was done measuring the low frequency/high frequency ratio (LF/HF). A non- linear analysis was carried out measuring the standard deviation of the instantaneous variation of RR intervals (SD1) and α-1 or a fractal analysis of RR interval complexity. A fasting blood sample was obtained to measure blood glucose and insulin and calculate the homeostasis model assessment for insulin resistance (HOMA-IR). Results: Among obese subjects HOMA-IR, LF/HF, α-1 and SD1 values were 2.6 ± 2.1, 2.4 ± 1.8, 1.2 ± 0.06 and 22.5 ± 10 respectively. The figures for normal weight subjects were 0.5 ± 0.1, 1.3 ± 0.2, 0.9 ± 0.3 and 26 ± 7.8 respectively. Conclusions: There is an association between spectral and fractal values of heart rate variability and HOMA-IR. These results may indicate a predominance of sympathetic control of heart rate among obese subjects.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.9 20152015-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000900005es10.4067/S0034-98872015000900005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Autonomic nervous system Heart rate Insulin resistance Obesity Overweight
spellingShingle	Autonomic nervous system Heart rate Insulin resistance Obesity Overweight Espinoza-Salinas,Alexis Zafra-Santos,Edson Pavez-Von Martens,Gustavo Cofré-Bolados,Cristian Lemus-Zúñiga,Jorge Sánchez-Aguilera,Pablo Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
description	Background: Heart rate variability analysis provides quantitative information about vagal and sympathetic modulation of cardiac function. Aim: To analyze the relationship between heart rate variability and insulin resistance in obese patients. Material and Methods: Male participants were studied, divided in 10 obese subjects aged 27 ± 2 years with a body mass index (BMI) of 31.2 ± 1.3 kg/m², 15 overweight subjects aged 24 ± 3 years with a BMI of 26.7 ± 1.5 kg/m² and 14 normal weight subjects aged 21 ± 2 years with a BMI of 22.5 ± 1.3 kg/m². Resting heart rate variability was measured in a period of 5 minutes. A spectral analysis was done measuring the low frequency/high frequency ratio (LF/HF). A non- linear analysis was carried out measuring the standard deviation of the instantaneous variation of RR intervals (SD1) and α-1 or a fractal analysis of RR interval complexity. A fasting blood sample was obtained to measure blood glucose and insulin and calculate the homeostasis model assessment for insulin resistance (HOMA-IR). Results: Among obese subjects HOMA-IR, LF/HF, α-1 and SD1 values were 2.6 ± 2.1, 2.4 ± 1.8, 1.2 ± 0.06 and 22.5 ± 10 respectively. The figures for normal weight subjects were 0.5 ± 0.1, 1.3 ± 0.2, 0.9 ± 0.3 and 26 ± 7.8 respectively. Conclusions: There is an association between spectral and fractal values of heart rate variability and HOMA-IR. These results may indicate a predominance of sympathetic control of heart rate among obese subjects.
author	Espinoza-Salinas,Alexis Zafra-Santos,Edson Pavez-Von Martens,Gustavo Cofré-Bolados,Cristian Lemus-Zúñiga,Jorge Sánchez-Aguilera,Pablo
author_facet	Espinoza-Salinas,Alexis Zafra-Santos,Edson Pavez-Von Martens,Gustavo Cofré-Bolados,Cristian Lemus-Zúñiga,Jorge Sánchez-Aguilera,Pablo
author_sort	Espinoza-Salinas,Alexis
title	Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
title_short	Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
title_full	Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
title_fullStr	Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
title_full_unstemmed	Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
title_sort	análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000900005
work_keys_str_mv	AT espinozasalinasalexis analisisdevariabilidaddelritmocardiacoysurelacionconlasensibilidadinsulinicaenpacientesobesosyconsobrepeso AT zafrasantosedson analisisdevariabilidaddelritmocardiacoysurelacionconlasensibilidadinsulinicaenpacientesobesosyconsobrepeso AT pavezvonmartensgustavo analisisdevariabilidaddelritmocardiacoysurelacionconlasensibilidadinsulinicaenpacientesobesosyconsobrepeso AT cofreboladoscristian analisisdevariabilidaddelritmocardiacoysurelacionconlasensibilidadinsulinicaenpacientesobesosyconsobrepeso AT lemuszunigajorge analisisdevariabilidaddelritmocardiacoysurelacionconlasensibilidadinsulinicaenpacientesobesosyconsobrepeso AT sanchezaguilerapablo analisisdevariabilidaddelritmocardiacoysurelacionconlasensibilidadinsulinicaenpacientesobesosyconsobrepeso
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Análisis de variabilidad del ritmo cardiaco y su relación con la sensibilidad insulínica en pacientes obesos y con sobrepeso

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