Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo

Background: Kidney transplantation is the best treatment for end stage kidney disease. The allograft allocation system considers immunological factors and time in waiting list, but not the age of donors or recipients, in spite that both have prognostic relevance. Aim: To study the fairness of the al...

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Autores principales:	González,Fernando, Rocca,Ximena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Kidney transplantation Patient care planning Unrelated donors Waiting lists
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001100007
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spelling	oai:scielo:S0034-988720150011000072016-01-19Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuoGonzález,FernandoRocca,Ximena Kidney transplantation Patient care planning Unrelated donors Waiting lists Background: Kidney transplantation is the best treatment for end stage kidney disease. The allograft allocation system considers immunological factors and time in waiting list, but not the age of donors or recipients, in spite that both have prognostic relevance. Aim: To study the fairness of the allograft allocation system considering the age of donors and recipients. Material and Methods: Based in the age distribution of donors and waiting list of patients for kidney transplantation, we constructed probability functions for receiving a graft as an allocation system based on age changes from a strict to a more lax criteria. Finally, we compared our model with the real transplants performed during 2012. Results: The probability distribution for receiving a kidney transplantation is displaced to the right compared with the age distribution of graft donors. This gap increases as the procuring hospitals enlist progressively older graft candidates without accepting older donors in parallel. An allocation system that maintains age parity between donors and recipients is fairer that other that allows lax criteria for the same allocation. This phenomenon is attenuated if the procurement acceptance criterion allows older donors. Conclusions: It is necessary to reduce the gap between donor and recipient ages for kidney transplantation to improve the fairness of the graft allocation system.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.11 20152015-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001100007es10.4067/S0034-98872015001100007
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Kidney transplantation Patient care planning Unrelated donors Waiting lists
spellingShingle	Kidney transplantation Patient care planning Unrelated donors Waiting lists González,Fernando Rocca,Ximena Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
description	Background: Kidney transplantation is the best treatment for end stage kidney disease. The allograft allocation system considers immunological factors and time in waiting list, but not the age of donors or recipients, in spite that both have prognostic relevance. Aim: To study the fairness of the allograft allocation system considering the age of donors and recipients. Material and Methods: Based in the age distribution of donors and waiting list of patients for kidney transplantation, we constructed probability functions for receiving a graft as an allocation system based on age changes from a strict to a more lax criteria. Finally, we compared our model with the real transplants performed during 2012. Results: The probability distribution for receiving a kidney transplantation is displaced to the right compared with the age distribution of graft donors. This gap increases as the procuring hospitals enlist progressively older graft candidates without accepting older donors in parallel. An allocation system that maintains age parity between donors and recipients is fairer that other that allows lax criteria for the same allocation. This phenomenon is attenuated if the procurement acceptance criterion allows older donors. Conclusions: It is necessary to reduce the gap between donor and recipient ages for kidney transplantation to improve the fairness of the graft allocation system.
author	González,Fernando Rocca,Ximena
author_facet	González,Fernando Rocca,Ximena
author_sort	González,Fernando
title	Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
title_short	Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
title_full	Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
title_fullStr	Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
title_full_unstemmed	Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
title_sort	un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001100007
work_keys_str_mv	AT gonzalezfernando unsistemadeasignaciondeorganosparatrasplantequenoconsiderelasedadesdedonanteyreceptoresinicuo AT roccaximena unsistemadeasignaciondeorganosparatrasplantequenoconsiderelasedadesdedonanteyreceptoresinicuo
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Un sistema de asignación de órganos para trasplante que no considere las edades de donante y receptor es inicuo

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