Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile

Background: Burkitt lymphoma has a low incidence, is highly aggressive, may be endemic, sporadic or associated with immunodeficiency and it has a high frequency of extranodal involvement. Overall and relapse free survival in HIV patients is 72 and 71% respectively. However, the current protocol in C...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Puga L,Bárbara, Bustamante K,Katherinne, Molina E,Javiera, Andrade M,Alejandro
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Antineoplastic protocols Burkitt lymphoma HIV
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001200001
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872015001200001
record_format	dspace
spelling	oai:scielo:S0034-988720150012000012016-02-29Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, ChilePuga L,BárbaraBustamante K,KatherinneMolina E,JavieraAndrade M,Alejandro Antineoplastic protocols Burkitt lymphoma HIV Background: Burkitt lymphoma has a low incidence, is highly aggressive, may be endemic, sporadic or associated with immunodeficiency and it has a high frequency of extranodal involvement. Overall and relapse free survival in HIV patients is 72 and 71% respectively. However, the current protocol in Chile considers a positive HIV serology as an exclusion criterion for intensive chemotherapy. Aim: To analyze the response to Burkitt lymphoma treatment among HIV positive patients. Material and Methods: All HIV positive patients with a Burkitt lymphoma treated using PANDA protocol in a public hospital were analyzed. Results: Eight male patients aged between 25 and 43 years, 63% in stage IV, were analyzed. All patients received an intensified chemotherapy regime, three of them without Rituximab. Complete remission was achieved in 87%. One patient was refractory to treatment and one patient relapsed at 5 months and died. Overall and relapse free survival were 58 and 60% respectively. All patients had episodes of high risk febrile neutropenia, but it did not cause deaths. Conclusions: In this group of HIV patients, intensive chemotherapy for Burkitt lymphoma had a high degree of effectiveness with a low relapse rate and high cure rate.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.12 20152015-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001200001es10.4067/S0034-98872015001200001
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antineoplastic protocols Burkitt lymphoma HIV
spellingShingle	Antineoplastic protocols Burkitt lymphoma HIV Puga L,Bárbara Bustamante K,Katherinne Molina E,Javiera Andrade M,Alejandro Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile
description	Background: Burkitt lymphoma has a low incidence, is highly aggressive, may be endemic, sporadic or associated with immunodeficiency and it has a high frequency of extranodal involvement. Overall and relapse free survival in HIV patients is 72 and 71% respectively. However, the current protocol in Chile considers a positive HIV serology as an exclusion criterion for intensive chemotherapy. Aim: To analyze the response to Burkitt lymphoma treatment among HIV positive patients. Material and Methods: All HIV positive patients with a Burkitt lymphoma treated using PANDA protocol in a public hospital were analyzed. Results: Eight male patients aged between 25 and 43 years, 63% in stage IV, were analyzed. All patients received an intensified chemotherapy regime, three of them without Rituximab. Complete remission was achieved in 87%. One patient was refractory to treatment and one patient relapsed at 5 months and died. Overall and relapse free survival were 58 and 60% respectively. All patients had episodes of high risk febrile neutropenia, but it did not cause deaths. Conclusions: In this group of HIV patients, intensive chemotherapy for Burkitt lymphoma had a high degree of effectiveness with a low relapse rate and high cure rate.
author	Puga L,Bárbara Bustamante K,Katherinne Molina E,Javiera Andrade M,Alejandro
author_facet	Puga L,Bárbara Bustamante K,Katherinne Molina E,Javiera Andrade M,Alejandro
author_sort	Puga L,Bárbara
title	Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile
title_short	Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile
title_full	Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile
title_fullStr	Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile
title_full_unstemmed	Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile
title_sort	linfoma de burkitt en pacientes hiv positivo tratados con quimioterapia intensiva en el hospital del salvador entre 2011 y 2014: protocolo nacional de cáncer del adulto, chile
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001200001
work_keys_str_mv	AT pugalbarbara linfomadeburkittenpacienteshivpositivotratadosconquimioterapiaintensivaenelhospitaldelsalvadorentre2011y2014protocolonacionaldecancerdeladultochile AT bustamantekkatherinne linfomadeburkittenpacienteshivpositivotratadosconquimioterapiaintensivaenelhospitaldelsalvadorentre2011y2014protocolonacionaldecancerdeladultochile AT molinaejaviera linfomadeburkittenpacienteshivpositivotratadosconquimioterapiaintensivaenelhospitaldelsalvadorentre2011y2014protocolonacionaldecancerdeladultochile AT andrademalejandro linfomadeburkittenpacienteshivpositivotratadosconquimioterapiaintensivaenelhospitaldelsalvadorentre2011y2014protocolonacionaldecancerdeladultochile
_version_	1718436854758375424

Linfoma de Burkitt en pacientes HIV positivo tratados con quimioterapia intensiva en el Hospital del Salvador entre 2011 y 2014: Protocolo Nacional de Cáncer del Adulto, Chile

Ejemplares similares