Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices

Background: Cardiac arrhythmias can be a part of cardiovascular involvement in some rheumatic diseases, but data about familial Mediterranean fever (FMF) are conflicting. Aim: To search for abnormalities in ventricular repolarization indices in FMF patients. Patients and Methods: Seventy seven FMF p...

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Autores principales:	Ahbap,Elbis, Sakaci,Tamer, Kara,Ekrem, Sahutoglu,Tuncay, Ozturk,Semi, Basturk,Taner, Koc,Yener, Sevinc,Mustafa, Akgol,Cuneyt, Ucar,Zuhal Atan, Kayalar,Arzu Ozdemir, Caglayan,Feyza Bayraktar, Gurbuz,Seyfettin, Unsal,Abdulkadir
Lenguaje:	English
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Arrhythmias, cardiac Familial Mediterranean fever Rheumatic diseases
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001200009
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spelling	oai:scielo:S0034-988720150012000092016-02-29Familial Mediterranean Fever is associated with abnormal ventricular repolarization indicesAhbap,ElbisSakaci,TamerKara,EkremSahutoglu,TuncayOzturk,SemiBasturk,TanerKoc,YenerSevinc,MustafaAkgol,CuneytUcar,Zuhal AtanKayalar,Arzu OzdemirCaglayan,Feyza BayraktarGurbuz,SeyfettinUnsal,Abdulkadir Arrhythmias, cardiac Familial Mediterranean fever Rheumatic diseases Background: Cardiac arrhythmias can be a part of cardiovascular involvement in some rheumatic diseases, but data about familial Mediterranean fever (FMF) are conflicting. Aim: To search for abnormalities in ventricular repolarization indices in FMF patients. Patients and Methods: Seventy seven FMF patients and 30 age/gender comparable healthy controls were included. All patients were attack free and subjects with disease or drugs that are known to alter cardiac electrophysiology were excluded. Electrocardiographic data were obtained and analyzed. Results: Twelve FMF patients had amyloidosis. QT and QTc intervals were within the normal ranges and similar between FMF patients and healthy controls. QT dispersion, peak to end interval of T wave (Tpe), Tpe/QT and Tpe/QTc ratios were significantly higher in FMF patients than in healthy controls. Patients with amyloidosis had significantly higher QT dispersion, Tpe, Tpe/QT and Tpe/QTc than their counterparts without FMF. Levels of proteinuria were moderately correlated with QT dispersion, Tpe, Tpe/QT and Tpe/QTc. Conclusions: FMF patients may have an increased risk for arrhythmias.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.12 20152015-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001200009en10.4067/S0034-98872015001200009
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Arrhythmias, cardiac Familial Mediterranean fever Rheumatic diseases
spellingShingle	Arrhythmias, cardiac Familial Mediterranean fever Rheumatic diseases Ahbap,Elbis Sakaci,Tamer Kara,Ekrem Sahutoglu,Tuncay Ozturk,Semi Basturk,Taner Koc,Yener Sevinc,Mustafa Akgol,Cuneyt Ucar,Zuhal Atan Kayalar,Arzu Ozdemir Caglayan,Feyza Bayraktar Gurbuz,Seyfettin Unsal,Abdulkadir Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices
description	Background: Cardiac arrhythmias can be a part of cardiovascular involvement in some rheumatic diseases, but data about familial Mediterranean fever (FMF) are conflicting. Aim: To search for abnormalities in ventricular repolarization indices in FMF patients. Patients and Methods: Seventy seven FMF patients and 30 age/gender comparable healthy controls were included. All patients were attack free and subjects with disease or drugs that are known to alter cardiac electrophysiology were excluded. Electrocardiographic data were obtained and analyzed. Results: Twelve FMF patients had amyloidosis. QT and QTc intervals were within the normal ranges and similar between FMF patients and healthy controls. QT dispersion, peak to end interval of T wave (Tpe), Tpe/QT and Tpe/QTc ratios were significantly higher in FMF patients than in healthy controls. Patients with amyloidosis had significantly higher QT dispersion, Tpe, Tpe/QT and Tpe/QTc than their counterparts without FMF. Levels of proteinuria were moderately correlated with QT dispersion, Tpe, Tpe/QT and Tpe/QTc. Conclusions: FMF patients may have an increased risk for arrhythmias.
author	Ahbap,Elbis Sakaci,Tamer Kara,Ekrem Sahutoglu,Tuncay Ozturk,Semi Basturk,Taner Koc,Yener Sevinc,Mustafa Akgol,Cuneyt Ucar,Zuhal Atan Kayalar,Arzu Ozdemir Caglayan,Feyza Bayraktar Gurbuz,Seyfettin Unsal,Abdulkadir
author_facet	Ahbap,Elbis Sakaci,Tamer Kara,Ekrem Sahutoglu,Tuncay Ozturk,Semi Basturk,Taner Koc,Yener Sevinc,Mustafa Akgol,Cuneyt Ucar,Zuhal Atan Kayalar,Arzu Ozdemir Caglayan,Feyza Bayraktar Gurbuz,Seyfettin Unsal,Abdulkadir
author_sort	Ahbap,Elbis
title	Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices
title_short	Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices
title_full	Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices
title_fullStr	Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices
title_full_unstemmed	Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices
title_sort	familial mediterranean fever is associated with abnormal ventricular repolarization indices
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015001200009
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Familial Mediterranean Fever is associated with abnormal ventricular repolarization indices

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