Resultados a largo plazo en trasplante renal de donantes con criterios expandidos

Background: Kidney transplantation of expanded criteria deceased donors (DCE) has become a common clinical practice. However, DCE outcomes are inferior compared to kidney transplants from standard criteria donors (DCS). Aim: To evaluate intermediate and long-term outcomes of DCE transplanted patient...

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Autores principales:	Valjalo,Ricardo, Reynolds,Enrique, Herrera,Patricia, Espinoza,Óscar, González,Fernando
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Aged Donor selection Graft rejection Graft survival Kidney transplantation
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100004
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spelling	oai:scielo:S0034-988720160001000042016-03-17Resultados a largo plazo en trasplante renal de donantes con criterios expandidosValjalo,RicardoReynolds,EnriqueHerrera,PatriciaEspinoza,ÓscarGonzález,Fernando Aged Donor selection Graft rejection Graft survival Kidney transplantation Background: Kidney transplantation of expanded criteria deceased donors (DCE) has become a common clinical practice. However, DCE outcomes are inferior compared to kidney transplants from standard criteria donors (DCS). Aim: To evaluate intermediate and long-term outcomes of DCE transplanted patients. Material and Methods: Cadaveric kidney transplants were evaluated using a retrospective cohort of eight consecutive years. Complications and long-term function of the transplant were assessed in DCE and DCS kidney recipients. Results: Of 213 patients analyzed, 34 (16%) underwent DCE transplantation. DCS recipients spent more time on the waiting list for transplantation (p = 0.04). DCE recipients showed higher frequency of surgical complications (p = 0.04), vascular complications (p = 0.02), acute transplant rejection (p = 0.05), and hospitalizations (p = 0.01). Creatinine (mg/dL) in DCE and DCS recipients was 2.3 and 1.5 respectively at year one (p < 0.01) and 2.6 and 1.6 respectively at year five (p < 0.01). Graft survival in the DCE group was significantly lower at 5 years (61 and 89% respectively, p < 0.01). Conclusions: DCE grafts are associated with lower survival, higher hospitalization rate and commonly develop surgical complications and rejections.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.1 20162016-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100004es10.4067/S0034-98872016000100004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Aged Donor selection Graft rejection Graft survival Kidney transplantation
spellingShingle	Aged Donor selection Graft rejection Graft survival Kidney transplantation Valjalo,Ricardo Reynolds,Enrique Herrera,Patricia Espinoza,Óscar González,Fernando Resultados a largo plazo en trasplante renal de donantes con criterios expandidos
description	Background: Kidney transplantation of expanded criteria deceased donors (DCE) has become a common clinical practice. However, DCE outcomes are inferior compared to kidney transplants from standard criteria donors (DCS). Aim: To evaluate intermediate and long-term outcomes of DCE transplanted patients. Material and Methods: Cadaveric kidney transplants were evaluated using a retrospective cohort of eight consecutive years. Complications and long-term function of the transplant were assessed in DCE and DCS kidney recipients. Results: Of 213 patients analyzed, 34 (16%) underwent DCE transplantation. DCS recipients spent more time on the waiting list for transplantation (p = 0.04). DCE recipients showed higher frequency of surgical complications (p = 0.04), vascular complications (p = 0.02), acute transplant rejection (p = 0.05), and hospitalizations (p = 0.01). Creatinine (mg/dL) in DCE and DCS recipients was 2.3 and 1.5 respectively at year one (p < 0.01) and 2.6 and 1.6 respectively at year five (p < 0.01). Graft survival in the DCE group was significantly lower at 5 years (61 and 89% respectively, p < 0.01). Conclusions: DCE grafts are associated with lower survival, higher hospitalization rate and commonly develop surgical complications and rejections.
author	Valjalo,Ricardo Reynolds,Enrique Herrera,Patricia Espinoza,Óscar González,Fernando
author_facet	Valjalo,Ricardo Reynolds,Enrique Herrera,Patricia Espinoza,Óscar González,Fernando
author_sort	Valjalo,Ricardo
title	Resultados a largo plazo en trasplante renal de donantes con criterios expandidos
title_short	Resultados a largo plazo en trasplante renal de donantes con criterios expandidos
title_full	Resultados a largo plazo en trasplante renal de donantes con criterios expandidos
title_fullStr	Resultados a largo plazo en trasplante renal de donantes con criterios expandidos
title_full_unstemmed	Resultados a largo plazo en trasplante renal de donantes con criterios expandidos
title_sort	resultados a largo plazo en trasplante renal de donantes con criterios expandidos
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100004
work_keys_str_mv	AT valjaloricardo resultadosalargoplazoentrasplanterenaldedonantesconcriteriosexpandidos AT reynoldsenrique resultadosalargoplazoentrasplanterenaldedonantesconcriteriosexpandidos AT herrerapatricia resultadosalargoplazoentrasplanterenaldedonantesconcriteriosexpandidos AT espinozaoscar resultadosalargoplazoentrasplanterenaldedonantesconcriteriosexpandidos AT gonzalezfernando resultadosalargoplazoentrasplanterenaldedonantesconcriteriosexpandidos
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Resultados a largo plazo en trasplante renal de donantes con criterios expandidos

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