Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio

Background: Consumption of illicit drugs (ID) has been associated with an increased risk of acute myocardial infarction (AMI). There is limited national evidence about the impact of substance use over the clinical presentation, management and outcomes of AMI patients. Aim: To describe the prevalence...

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Autores principales:	Bartolucci,Jorge, Nazzal N,Carolina, Verdugo,Fernando J, Prieto,Juan Carlos, Sepúlveda,Pablo, Corbalán,Ramón
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Cannabis Cocaine Hospital Mortality Myocardial Infarction Street Drugs
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100006
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spelling	oai:scielo:S0034-988720160001000062016-03-17Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardioBartolucci,JorgeNazzal N,CarolinaVerdugo,Fernando JPrieto,Juan CarlosSepúlveda,PabloCorbalán,Ramón Cannabis Cocaine Hospital Mortality Myocardial Infarction Street Drugs Background: Consumption of illicit drugs (ID) has been associated with an increased risk of acute myocardial infarction (AMI). There is limited national evidence about the impact of substance use over the clinical presentation, management and outcomes of AMI patients. Aim: To describe the prevalence of ID consumption in patients within the Chilean Registry of Myocardial Infarction (GEMI), comparing clinical characteristics, management and outcome according to consumption status. Material and Methods: We reviewed data from the GEMI registry between 2001 and 2013, identifying 18,048 patients with AMI. The sample was stratified according to presence or absence of previous ID consumption, comparing different demographic and clinical variables between groups. Results: Two hundred eighty five patients (1.6%) had history of ID consumption (cocaine in 66%, cannabis in 35% and central nervous system stimulants in 24.0%). Compared with non-users, ID consumers were younger, predominantly male and had a lower prevalence of cardiovascular risk factors, except for tobacco smoking (86.3% and 42.5% respectively, p < 0.01). Among consumers, there was a higher percentage of ST segment elevation (85.2% and 67.8% respectively, p < 0.01) and anterior wall AMI (59.9 and 49.5% respectively, p = 0.01). Additionally, they had a higher rate of primary angioplasty (48.8% and 25.5% respectively, p < 0.01). There was no difference in hospital mortality between groups when stratified by age. Conclusions: A low percentage of patients with AMI had a previous history of ID consumption in our national setting. These patients were younger and had a greater frequency of ST segment elevation AMI, which probably determined a more invasive management.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.1 20162016-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100006es10.4067/S0034-98872016000100006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cannabis Cocaine Hospital Mortality Myocardial Infarction Street Drugs
spellingShingle	Cannabis Cocaine Hospital Mortality Myocardial Infarction Street Drugs Bartolucci,Jorge Nazzal N,Carolina Verdugo,Fernando J Prieto,Juan Carlos Sepúlveda,Pablo Corbalán,Ramón Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
description	Background: Consumption of illicit drugs (ID) has been associated with an increased risk of acute myocardial infarction (AMI). There is limited national evidence about the impact of substance use over the clinical presentation, management and outcomes of AMI patients. Aim: To describe the prevalence of ID consumption in patients within the Chilean Registry of Myocardial Infarction (GEMI), comparing clinical characteristics, management and outcome according to consumption status. Material and Methods: We reviewed data from the GEMI registry between 2001 and 2013, identifying 18,048 patients with AMI. The sample was stratified according to presence or absence of previous ID consumption, comparing different demographic and clinical variables between groups. Results: Two hundred eighty five patients (1.6%) had history of ID consumption (cocaine in 66%, cannabis in 35% and central nervous system stimulants in 24.0%). Compared with non-users, ID consumers were younger, predominantly male and had a lower prevalence of cardiovascular risk factors, except for tobacco smoking (86.3% and 42.5% respectively, p < 0.01). Among consumers, there was a higher percentage of ST segment elevation (85.2% and 67.8% respectively, p < 0.01) and anterior wall AMI (59.9 and 49.5% respectively, p = 0.01). Additionally, they had a higher rate of primary angioplasty (48.8% and 25.5% respectively, p < 0.01). There was no difference in hospital mortality between groups when stratified by age. Conclusions: A low percentage of patients with AMI had a previous history of ID consumption in our national setting. These patients were younger and had a greater frequency of ST segment elevation AMI, which probably determined a more invasive management.
author	Bartolucci,Jorge Nazzal N,Carolina Verdugo,Fernando J Prieto,Juan Carlos Sepúlveda,Pablo Corbalán,Ramón
author_facet	Bartolucci,Jorge Nazzal N,Carolina Verdugo,Fernando J Prieto,Juan Carlos Sepúlveda,Pablo Corbalán,Ramón
author_sort	Bartolucci,Jorge
title	Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
title_short	Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
title_full	Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
title_fullStr	Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
title_full_unstemmed	Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
title_sort	características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100006
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Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio

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