Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica

Background: Sentinel node detection localizes the first node that drains a malignant lesion aiming to detect tumor dissemination. Aim: To assess the yield of sentinel node detection in breast cancer, using pre or intraoperative scintigraphy. Material and Methods: Review of medical records of patient...

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Autores principales:	Humeres A,Pamela, González,Javiera, González,Patricio, Waugh,Enrique, Gómez,Fernando, Alliende,Isabel
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Breast neoplasms Lymphatic metastasis Radionuclide imaging Sentinel lymph node biopsy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100009
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spelling	oai:scielo:S0034-988720160001000092016-03-17Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgicaHumeres A,PamelaGonzález,JavieraGonzález,PatricioWaugh,EnriqueGómez,FernandoAlliende,Isabel Breast neoplasms Lymphatic metastasis Radionuclide imaging Sentinel lymph node biopsy Background: Sentinel node detection localizes the first node that drains a malignant lesion aiming to detect tumor dissemination. Aim: To assess the yield of sentinel node detection in breast cancer, using pre or intraoperative scintigraphy. Material and Methods: Review of medical records of patients with breast cancer who had a scintigraphic detection of sentinel nodes. Lymph node scintigraphy and surgery were performed in the same day. Results: We studied 174 women aged 53 ± 13 years, operated with a diagnosis of breast cancer, including six highly suspicious lesions in the contralateral breast (totaling 180 studied breasts). Preoperative scintigraphy showed a sentinel node in 174 of 180 breasts (97%). Intraoperative gamma probe confirmed the presence of the sentinel node in the same 174 breasts and detected an additional one reaching a detection yield of 97%. Four patients in whom a sentinel node was not detected in the preoperative scintigraphy, had macrometastases. Frozen section biopsies were available in 177 of 180 breasts. Metastases were informed in 45 patients who underwent axillary lymph node dissection, plus one additional patient with a suspicious lesion. Conclusions: A high rate of sentinel node detection in the preoperative scintigraphy was observed. Most sentinel nodes not detected with nuclear medicine had macrometastases. In 71% of patients, the detection of sentinel node avoided axillary lymph node dissection.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.1 20162016-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100009es10.4067/S0034-98872016000100009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Breast neoplasms Lymphatic metastasis Radionuclide imaging Sentinel lymph node biopsy
spellingShingle	Breast neoplasms Lymphatic metastasis Radionuclide imaging Sentinel lymph node biopsy Humeres A,Pamela González,Javiera González,Patricio Waugh,Enrique Gómez,Fernando Alliende,Isabel Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
description	Background: Sentinel node detection localizes the first node that drains a malignant lesion aiming to detect tumor dissemination. Aim: To assess the yield of sentinel node detection in breast cancer, using pre or intraoperative scintigraphy. Material and Methods: Review of medical records of patients with breast cancer who had a scintigraphic detection of sentinel nodes. Lymph node scintigraphy and surgery were performed in the same day. Results: We studied 174 women aged 53 ± 13 years, operated with a diagnosis of breast cancer, including six highly suspicious lesions in the contralateral breast (totaling 180 studied breasts). Preoperative scintigraphy showed a sentinel node in 174 of 180 breasts (97%). Intraoperative gamma probe confirmed the presence of the sentinel node in the same 174 breasts and detected an additional one reaching a detection yield of 97%. Four patients in whom a sentinel node was not detected in the preoperative scintigraphy, had macrometastases. Frozen section biopsies were available in 177 of 180 breasts. Metastases were informed in 45 patients who underwent axillary lymph node dissection, plus one additional patient with a suspicious lesion. Conclusions: A high rate of sentinel node detection in the preoperative scintigraphy was observed. Most sentinel nodes not detected with nuclear medicine had macrometastases. In 71% of patients, the detection of sentinel node avoided axillary lymph node dissection.
author	Humeres A,Pamela González,Javiera González,Patricio Waugh,Enrique Gómez,Fernando Alliende,Isabel
author_facet	Humeres A,Pamela González,Javiera González,Patricio Waugh,Enrique Gómez,Fernando Alliende,Isabel
author_sort	Humeres A,Pamela
title	Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
title_short	Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
title_full	Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
title_fullStr	Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
title_full_unstemmed	Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
title_sort	linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100009
work_keys_str_mv	AT humeresapamela linfonodocentinelaencancerdemamacorrelacionentredeteccionisotopicayquirurgica AT gonzalezjaviera linfonodocentinelaencancerdemamacorrelacionentredeteccionisotopicayquirurgica AT gonzalezpatricio linfonodocentinelaencancerdemamacorrelacionentredeteccionisotopicayquirurgica AT waughenrique linfonodocentinelaencancerdemamacorrelacionentredeteccionisotopicayquirurgica AT gomezfernando linfonodocentinelaencancerdemamacorrelacionentredeteccionisotopicayquirurgica AT alliendeisabel linfonodocentinelaencancerdemamacorrelacionentredeteccionisotopicayquirurgica
_version_	1718436861109600256

Linfonodo centinela en cáncer de mama: correlación entre detección isotópica y quirúrgica

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