Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico

Pediatric Status Epilepticus (SE) is an emergency situation with high morbidity and mortality that requires early and aggressive management. The minimum time criterion to define SE was reduced from 30 to 5 minutes, defined as continuous seizure activity or rapidly recurrent seizures without resumpti...

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Autores principales:	Vargas L,Carmen Paz, Varela E,Ximena, Kleinsteuber S,Karin, Cortés Z,Rocío, Avaria B,María de los Ángeles
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Epilepsy Refractory Status Seizures Status Epilepticus
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100011
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spelling	oai:scielo:S0034-988720160001000112016-03-17Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepilépticoVargas L,Carmen PazVarela E,XimenaKleinsteuber S,KarinCortés Z,RocíoAvaria B,María de los Ángeles Epilepsy Refractory Status Seizures Status Epilepticus Pediatric Status Epilepticus (SE) is an emergency situation with high morbidity and mortality that requires early and aggressive management. The minimum time criterion to define SE was reduced from 30 to 5 minutes, defined as continuous seizure activity or rapidly recurrent seizures without resumption of consciousness for more than 5 minutes. This definition considers that seizures that persist for > 5 minutes are likely to do so for more than 30 min. Those that persist for more than 30 minutes are more difficult to treat. Refractory SE is the condition that extends beyond 60-120 minutes and requires anesthetic management. Super-refractory SE is the state of no response to anesthetic management or relapse during withdrawal of these drugs. The aim of this review is to provide and update on convulsive SE concepts, pathophysiology, etiology, available antiepileptic treatment and propose a rational management scheme. A literature search of articles published between January 1993 and January 2013, focused on pediatric population was performed. The evidence about management in children is limited, mostly corresponds to case series of patients grouped by diagnosis, mainly adults. These publications show treatment alternatives such as immunotherapy, ketogenic diet, surgery and hypothermia. A 35% mortality, 26% of neurological sequelae and 35% of recovery to baseline condition is described on patients evolution.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.1 20162016-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100011es10.4067/S0034-98872016000100011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Epilepsy Refractory Status Seizures Status Epilepticus
spellingShingle	Epilepsy Refractory Status Seizures Status Epilepticus Vargas L,Carmen Paz Varela E,Ximena Kleinsteuber S,Karin Cortés Z,Rocío Avaria B,María de los Ángeles Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
description	Pediatric Status Epilepticus (SE) is an emergency situation with high morbidity and mortality that requires early and aggressive management. The minimum time criterion to define SE was reduced from 30 to 5 minutes, defined as continuous seizure activity or rapidly recurrent seizures without resumption of consciousness for more than 5 minutes. This definition considers that seizures that persist for > 5 minutes are likely to do so for more than 30 min. Those that persist for more than 30 minutes are more difficult to treat. Refractory SE is the condition that extends beyond 60-120 minutes and requires anesthetic management. Super-refractory SE is the state of no response to anesthetic management or relapse during withdrawal of these drugs. The aim of this review is to provide and update on convulsive SE concepts, pathophysiology, etiology, available antiepileptic treatment and propose a rational management scheme. A literature search of articles published between January 1993 and January 2013, focused on pediatric population was performed. The evidence about management in children is limited, mostly corresponds to case series of patients grouped by diagnosis, mainly adults. These publications show treatment alternatives such as immunotherapy, ketogenic diet, surgery and hypothermia. A 35% mortality, 26% of neurological sequelae and 35% of recovery to baseline condition is described on patients evolution.
author	Vargas L,Carmen Paz Varela E,Ximena Kleinsteuber S,Karin Cortés Z,Rocío Avaria B,María de los Ángeles
author_facet	Vargas L,Carmen Paz Varela E,Ximena Kleinsteuber S,Karin Cortés Z,Rocío Avaria B,María de los Ángeles
author_sort	Vargas L,Carmen Paz
title	Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
title_short	Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
title_full	Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
title_fullStr	Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
title_full_unstemmed	Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
title_sort	revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000100011
work_keys_str_mv	AT vargaslcarmenpaz revisiondelestadoepilepticoconvulsivopediatricoysumanejoantiepileptico AT varelaeximena revisiondelestadoepilepticoconvulsivopediatricoysumanejoantiepileptico AT kleinsteuberskarin revisiondelestadoepilepticoconvulsivopediatricoysumanejoantiepileptico AT corteszrocio revisiondelestadoepilepticoconvulsivopediatricoysumanejoantiepileptico AT avariabmariadelosangeles revisiondelestadoepilepticoconvulsivopediatricoysumanejoantiepileptico
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Revisión del estado epiléptico convulsivo pediátrico y su manejo antiepiléptico

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