Enfermedad celíaca.Revisión
The prevalence of Celiac disease in the general population is approximately 1% and remains undiagnosed in a significant proportion of individuals. Its clinical presentation includes the classical malabsorption syndrome, unspecific and extra-intestinal manifestations, and silent celiac disease. The s...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2016
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oai:scielo:S0034-988720160002000102016-04-13Enfermedad celíaca.RevisiónMoscoso J,FelipeQuera P,Rodrigo Autoimmunity Celiac disease Diet gluten free Glutens Malabsorption syndromes The prevalence of Celiac disease in the general population is approximately 1% and remains undiagnosed in a significant proportion of individuals. Its clinical presentation includes the classical malabsorption syndrome, unspecific and extra-intestinal manifestations, and silent celiac disease. The serologic diagnosis has an elevated sensitivity and specificity and, at least in adult population, it must be confirmed by biopsy in every case. Diagnosis in subjects already on gluten free diet includes HLA typing and gluten challenge with posterior serologic and histologic evaluation. The core of the treatment is the gluten free diet, which must be supervised by an expert nutritionist. Monitoring must be performed with serology beginning at 3-6 months, and with histology two years after the diagnosis, unless the clinical response is poor. Poor disease control is associated with complications such as lymphoma and small bowel adenocarcinoma. In the future, it is likely that new pharmacologic therapies will be available for the management of celiac disease.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.2 20162016-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000200010es10.4067/S0034-98872016000200010 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Autoimmunity Celiac disease Diet gluten free Glutens Malabsorption syndromes |
| spellingShingle |
Autoimmunity Celiac disease Diet gluten free Glutens Malabsorption syndromes Moscoso J,Felipe Quera P,Rodrigo Enfermedad celíaca.Revisión |
| description |
The prevalence of Celiac disease in the general population is approximately 1% and remains undiagnosed in a significant proportion of individuals. Its clinical presentation includes the classical malabsorption syndrome, unspecific and extra-intestinal manifestations, and silent celiac disease. The serologic diagnosis has an elevated sensitivity and specificity and, at least in adult population, it must be confirmed by biopsy in every case. Diagnosis in subjects already on gluten free diet includes HLA typing and gluten challenge with posterior serologic and histologic evaluation. The core of the treatment is the gluten free diet, which must be supervised by an expert nutritionist. Monitoring must be performed with serology beginning at 3-6 months, and with histology two years after the diagnosis, unless the clinical response is poor. Poor disease control is associated with complications such as lymphoma and small bowel adenocarcinoma. In the future, it is likely that new pharmacologic therapies will be available for the management of celiac disease. |
| author |
Moscoso J,Felipe Quera P,Rodrigo |
| author_facet |
Moscoso J,Felipe Quera P,Rodrigo |
| author_sort |
Moscoso J,Felipe |
| title |
Enfermedad celíaca.Revisión |
| title_short |
Enfermedad celíaca.Revisión |
| title_full |
Enfermedad celíaca.Revisión |
| title_fullStr |
Enfermedad celíaca.Revisión |
| title_full_unstemmed |
Enfermedad celíaca.Revisión |
| title_sort |
enfermedad celíaca.revisión |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2016 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000200010 |
| work_keys_str_mv |
AT moscosojfelipe enfermedadceliacarevision AT queraprodrigo enfermedadceliacarevision |
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