Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana

Background: Thyroid dysfunction is common among patients infected with human immunodeficiency virus (HIV). It presents in different forms and has a multifactorial etiology. Aim: To determine the prevalence and features of thyroid dysfunction among patients infected with HIV. Material and Methods: A...

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Autores principales: Báez,María Soledad, Zapata Silva,Andrea, López Benavides,María Isabel, Wilson,Gonzalo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2016
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000300008
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spelling oai:scielo:S0034-988720160003000082016-06-13Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humanaBáez,María SoledadZapata Silva,AndreaLópez Benavides,María IsabelWilson,Gonzalo HIV infections Thyroid diseases Thyroxine Background: Thyroid dysfunction is common among patients infected with human immunodeficiency virus (HIV). It presents in different forms and has a multifactorial etiology. Aim: To determine the prevalence and features of thyroid dysfunction among patients infected with HIV. Material and Methods: A cross-sectional study of 127 patients infected with HIV aged 19 to 75 years (85% males). Patients with previous diagnoses of endocrine diseases and pregnant women were excluded. Participants responded a questionnaire about symptoms and the evolution of HIV infection. A blood sample was obtained to measure thyroid stimulating hormone, free thyroxin, viral load and CD4 count. Results: Hypothyroidism was found 13 cases, hyperthyroidism in one case and hypothyroxinemia in eight cases. No difference in symptoms was found between patients with or without thyroid dysfunction. No significant differences were observed in CD4 count or the prevalence of co-infection with Hepatitis B virus among patients with thyroid dysfunction. No association between antiretroviral agents and thyroid dysfunction was observed. Conclusions: The thyroid abnormalities found in this group of HIV infected patients were usually asymptomatic. It may be advisable to systematically assess thyroid function in HIV infected patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.3 20162016-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000300008es10.4067/S0034-98872016000300008
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic HIV infections
Thyroid diseases
Thyroxine
spellingShingle HIV infections
Thyroid diseases
Thyroxine
Báez,María Soledad
Zapata Silva,Andrea
López Benavides,María Isabel
Wilson,Gonzalo
Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
description Background: Thyroid dysfunction is common among patients infected with human immunodeficiency virus (HIV). It presents in different forms and has a multifactorial etiology. Aim: To determine the prevalence and features of thyroid dysfunction among patients infected with HIV. Material and Methods: A cross-sectional study of 127 patients infected with HIV aged 19 to 75 years (85% males). Patients with previous diagnoses of endocrine diseases and pregnant women were excluded. Participants responded a questionnaire about symptoms and the evolution of HIV infection. A blood sample was obtained to measure thyroid stimulating hormone, free thyroxin, viral load and CD4 count. Results: Hypothyroidism was found 13 cases, hyperthyroidism in one case and hypothyroxinemia in eight cases. No difference in symptoms was found between patients with or without thyroid dysfunction. No significant differences were observed in CD4 count or the prevalence of co-infection with Hepatitis B virus among patients with thyroid dysfunction. No association between antiretroviral agents and thyroid dysfunction was observed. Conclusions: The thyroid abnormalities found in this group of HIV infected patients were usually asymptomatic. It may be advisable to systematically assess thyroid function in HIV infected patients.
author Báez,María Soledad
Zapata Silva,Andrea
López Benavides,María Isabel
Wilson,Gonzalo
author_facet Báez,María Soledad
Zapata Silva,Andrea
López Benavides,María Isabel
Wilson,Gonzalo
author_sort Báez,María Soledad
title Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
title_short Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
title_full Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
title_fullStr Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
title_full_unstemmed Alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
title_sort alteraciones tiroideas en pacientes infectados con el virus de inmunodeficiencia humana
publisher Sociedad Médica de Santiago
publishDate 2016
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000300008
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