Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos

Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) reduces disability in patients with ischemic stroke. However, its implementation in Chilean public general hospitals has been slow and faces some difficulties. Aim: To analyze the results of an intravenous thr...

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Autores principales:	Guevara O,Carlos, Bulatova,Kateryna, Aravena,Felipe, Caba,Sheila, Monsalve,Juan, Lara,Hugo, Nieto,Elena, Navarrete,Isabel, Morales,Marcelo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Stroke Thrombolytic Therapy Tissue Plasminogen Activator
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400004
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spelling	oai:scielo:S0034-988720160004000042016-07-01Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casosGuevara O,CarlosBulatova,KaterynaAravena,FelipeCaba,SheilaMonsalve,JuanLara,HugoNieto,ElenaNavarrete,IsabelMorales,Marcelo Stroke Thrombolytic Therapy Tissue Plasminogen Activator Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) reduces disability in patients with ischemic stroke. However, its implementation in Chilean public general hospitals has been slow and faces some difficulties. Aim: To analyze the results of an intravenous thrombolysis protocol implementation in a public general hospital. Material and Methods: During a lapse of 28 months a standardized protocol for intravenous thrombolysis implemented in the emergency room of a public hospital, was prospectively evaluated. Fifty four patients with ischemic stroke were treated and assessed three months later as outpatients. Results: At three months of follow-up, 66.4% of patients subjected to thrombolysis had a favorable evolution, defined as having 0 to 1 points in the modified Rankin scale. Intracerebral hemorrhage rate was 11.1%, including 5.5% of symptomatic intracerebral hemorrhage. Four percent of patients had systemic bleeding complications after thrombolysis. The mortality rate was 14.8%. Conclusions: The success rates, mortality, and complications rate were comparable to the results obtained in international studies, despite of the absence of a stroke unit to manage stroke and its complications.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.4 20162016-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400004es10.4067/S0034-98872016000400004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Stroke Thrombolytic Therapy Tissue Plasminogen Activator
spellingShingle	Stroke Thrombolytic Therapy Tissue Plasminogen Activator Guevara O,Carlos Bulatova,Kateryna Aravena,Felipe Caba,Sheila Monsalve,Juan Lara,Hugo Nieto,Elena Navarrete,Isabel Morales,Marcelo Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
description	Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) reduces disability in patients with ischemic stroke. However, its implementation in Chilean public general hospitals has been slow and faces some difficulties. Aim: To analyze the results of an intravenous thrombolysis protocol implementation in a public general hospital. Material and Methods: During a lapse of 28 months a standardized protocol for intravenous thrombolysis implemented in the emergency room of a public hospital, was prospectively evaluated. Fifty four patients with ischemic stroke were treated and assessed three months later as outpatients. Results: At three months of follow-up, 66.4% of patients subjected to thrombolysis had a favorable evolution, defined as having 0 to 1 points in the modified Rankin scale. Intracerebral hemorrhage rate was 11.1%, including 5.5% of symptomatic intracerebral hemorrhage. Four percent of patients had systemic bleeding complications after thrombolysis. The mortality rate was 14.8%. Conclusions: The success rates, mortality, and complications rate were comparable to the results obtained in international studies, despite of the absence of a stroke unit to manage stroke and its complications.
author	Guevara O,Carlos Bulatova,Kateryna Aravena,Felipe Caba,Sheila Monsalve,Juan Lara,Hugo Nieto,Elena Navarrete,Isabel Morales,Marcelo
author_facet	Guevara O,Carlos Bulatova,Kateryna Aravena,Felipe Caba,Sheila Monsalve,Juan Lara,Hugo Nieto,Elena Navarrete,Isabel Morales,Marcelo
author_sort	Guevara O,Carlos
title	Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
title_short	Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
title_full	Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
title_fullStr	Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
title_full_unstemmed	Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
title_sort	trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de chile: análisis prospectivo de 54 casos
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400004
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Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos

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