Compromiso renal en síndrome de Poems: Caso clínico

POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolact...

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Autor principal: Vega,Jorge
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2016
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400014
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spelling oai:scielo:S0034-988720160004000142016-07-01Compromiso renal en síndrome de Poems: Caso clínicoVega,Jorge Kidney Failure, Chronic Multiple Myeloma Renal Insufficiency, Chronic Vascular Endothelial Growth Factors POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolactinemia, adrenal insufficiency, hepatosplenomegaly, lymphadenopathy, thyroid and parotid enlargement, Castleman’s disease, papilledema, stiff and hyperpigmented skin, white nails, clubbing, ascites and chronic diarrhea. She had also a nephropathy characterized by microscopic hematuria, proteinuria, renal insufficiency and a unilateral kidney retraction. She was treated with melphalan and prednisone, achieving remission of the disease and nephropathy. She survived twelve years and died due to a myocardial infarction 20 years after POEMS diagnosis.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.4 20162016-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400014es10.4067/S0034-98872016000400014
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Kidney Failure, Chronic
Multiple Myeloma
Renal Insufficiency, Chronic
Vascular Endothelial Growth Factors
spellingShingle Kidney Failure, Chronic
Multiple Myeloma
Renal Insufficiency, Chronic
Vascular Endothelial Growth Factors
Vega,Jorge
Compromiso renal en síndrome de Poems: Caso clínico
description POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolactinemia, adrenal insufficiency, hepatosplenomegaly, lymphadenopathy, thyroid and parotid enlargement, Castleman’s disease, papilledema, stiff and hyperpigmented skin, white nails, clubbing, ascites and chronic diarrhea. She had also a nephropathy characterized by microscopic hematuria, proteinuria, renal insufficiency and a unilateral kidney retraction. She was treated with melphalan and prednisone, achieving remission of the disease and nephropathy. She survived twelve years and died due to a myocardial infarction 20 years after POEMS diagnosis.
author Vega,Jorge
author_facet Vega,Jorge
author_sort Vega,Jorge
title Compromiso renal en síndrome de Poems: Caso clínico
title_short Compromiso renal en síndrome de Poems: Caso clínico
title_full Compromiso renal en síndrome de Poems: Caso clínico
title_fullStr Compromiso renal en síndrome de Poems: Caso clínico
title_full_unstemmed Compromiso renal en síndrome de Poems: Caso clínico
title_sort compromiso renal en síndrome de poems: caso clínico
publisher Sociedad Médica de Santiago
publishDate 2016
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400014
work_keys_str_mv AT vegajorge compromisorenalensindromedepoemscasoclinico
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