Compromiso renal en síndrome de Poems: Caso clínico
POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolact...
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Sociedad Médica de Santiago
2016
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oai:scielo:S0034-988720160004000142016-07-01Compromiso renal en síndrome de Poems: Caso clínicoVega,Jorge Kidney Failure, Chronic Multiple Myeloma Renal Insufficiency, Chronic Vascular Endothelial Growth Factors POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolactinemia, adrenal insufficiency, hepatosplenomegaly, lymphadenopathy, thyroid and parotid enlargement, Castlemans disease, papilledema, stiff and hyperpigmented skin, white nails, clubbing, ascites and chronic diarrhea. She had also a nephropathy characterized by microscopic hematuria, proteinuria, renal insufficiency and a unilateral kidney retraction. She was treated with melphalan and prednisone, achieving remission of the disease and nephropathy. She survived twelve years and died due to a myocardial infarction 20 years after POEMS diagnosis.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.4 20162016-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400014es10.4067/S0034-98872016000400014 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Kidney Failure, Chronic Multiple Myeloma Renal Insufficiency, Chronic Vascular Endothelial Growth Factors |
spellingShingle |
Kidney Failure, Chronic Multiple Myeloma Renal Insufficiency, Chronic Vascular Endothelial Growth Factors Vega,Jorge Compromiso renal en síndrome de Poems: Caso clínico |
description |
POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolactinemia, adrenal insufficiency, hepatosplenomegaly, lymphadenopathy, thyroid and parotid enlargement, Castlemans disease, papilledema, stiff and hyperpigmented skin, white nails, clubbing, ascites and chronic diarrhea. She had also a nephropathy characterized by microscopic hematuria, proteinuria, renal insufficiency and a unilateral kidney retraction. She was treated with melphalan and prednisone, achieving remission of the disease and nephropathy. She survived twelve years and died due to a myocardial infarction 20 years after POEMS diagnosis. |
author |
Vega,Jorge |
author_facet |
Vega,Jorge |
author_sort |
Vega,Jorge |
title |
Compromiso renal en síndrome de Poems: Caso clínico |
title_short |
Compromiso renal en síndrome de Poems: Caso clínico |
title_full |
Compromiso renal en síndrome de Poems: Caso clínico |
title_fullStr |
Compromiso renal en síndrome de Poems: Caso clínico |
title_full_unstemmed |
Compromiso renal en síndrome de Poems: Caso clínico |
title_sort |
compromiso renal en síndrome de poems: caso clínico |
publisher |
Sociedad Médica de Santiago |
publishDate |
2016 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000400014 |
work_keys_str_mv |
AT vegajorge compromisorenalensindromedepoemscasoclinico |
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1718436878513864704 |