Contractilidad ventricular: Fisiología y proyección clínica
The contractile state of the heart is the result of myocardial contractility, the intrinsic mechanism that regulates the force and the shortening of the ventricle and determines the ventricular ejection volume. However, the ejection volume is also modulated by ventricular preload (diastolic ventricu...
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Sociedad Médica de Santiago
2016
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oai:scielo:S0034-988720160006000122016-10-03Contractilidad ventricular: Fisiología y proyección clínicaDomenech,Raúl JParra,Víctor M Cardiovascular Physiological Phenomena Cardiovascular System Myocardial Contraction Physiology The contractile state of the heart is the result of myocardial contractility, the intrinsic mechanism that regulates the force and the shortening of the ventricle and determines the ventricular ejection volume. However, the ejection volume is also modulated by ventricular preload (diastolic ventricular volume) and afterload (resistance to ejection). Accordingly, a decrease in contractility may be masked by changes in preload or afterload, maintaining a normal ejection volume and delaying the diagnosis of myocardial damage. Thus, it is necessary to develop a non-invasive method to measure contractility in the clinical practice. We review in this article the basic principles of cardiac contraction, the concept of contractility and its measurement with the ventricular pressure-volume loop, an experimental method that also measures most of the hemodynamic variables of the cardiac cycle including preload, afterload, ventricular work, ventricular lusitropy and arterial elastance. This method has been recently validated in cardiac patients and allows to evaluate the evolution of contractility in heart failure in a non invasive way. Although some modifications are still necessary, it will probably have an extensive use in practical cardiology in the near future.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.6 20162016-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000600012es10.4067/S0034-98872016000600012 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Cardiovascular Physiological Phenomena Cardiovascular System Myocardial Contraction Physiology |
| spellingShingle |
Cardiovascular Physiological Phenomena Cardiovascular System Myocardial Contraction Physiology Domenech,Raúl J Parra,Víctor M Contractilidad ventricular: Fisiología y proyección clínica |
| description |
The contractile state of the heart is the result of myocardial contractility, the intrinsic mechanism that regulates the force and the shortening of the ventricle and determines the ventricular ejection volume. However, the ejection volume is also modulated by ventricular preload (diastolic ventricular volume) and afterload (resistance to ejection). Accordingly, a decrease in contractility may be masked by changes in preload or afterload, maintaining a normal ejection volume and delaying the diagnosis of myocardial damage. Thus, it is necessary to develop a non-invasive method to measure contractility in the clinical practice. We review in this article the basic principles of cardiac contraction, the concept of contractility and its measurement with the ventricular pressure-volume loop, an experimental method that also measures most of the hemodynamic variables of the cardiac cycle including preload, afterload, ventricular work, ventricular lusitropy and arterial elastance. This method has been recently validated in cardiac patients and allows to evaluate the evolution of contractility in heart failure in a non invasive way. Although some modifications are still necessary, it will probably have an extensive use in practical cardiology in the near future. |
| author |
Domenech,Raúl J Parra,Víctor M |
| author_facet |
Domenech,Raúl J Parra,Víctor M |
| author_sort |
Domenech,Raúl J |
| title |
Contractilidad ventricular: Fisiología y proyección clínica |
| title_short |
Contractilidad ventricular: Fisiología y proyección clínica |
| title_full |
Contractilidad ventricular: Fisiología y proyección clínica |
| title_fullStr |
Contractilidad ventricular: Fisiología y proyección clínica |
| title_full_unstemmed |
Contractilidad ventricular: Fisiología y proyección clínica |
| title_sort |
contractilidad ventricular: fisiología y proyección clínica |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2016 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000600012 |
| work_keys_str_mv |
AT domenechraulj contractilidadventricularfisiologiayproyeccionclinica AT parravictorm contractilidadventricularfisiologiayproyeccionclinica |
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