Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case
High activity antiretroviral therapy may exacerbate the activity of ergot alkaloids due to an inhibition of cytochrome P450. We report a 57 years old female with AIDS treated with lamivudine, zidovudine, atazanavir, ritonavir and cotrimoxazole presenting with ischemic signs in the four limbs. There...
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Sociedad Médica de Santiago
2016
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oai:scielo:S0034-988720160006000172016-10-03Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one caseCifuentes M,DanielBlanco L,SergioRamírez F,Camila Acquired Immunodeficiency Syndrome Ergotism Ischemia High activity antiretroviral therapy may exacerbate the activity of ergot alkaloids due to an inhibition of cytochrome P450. We report a 57 years old female with AIDS treated with lamivudine, zidovudine, atazanavir, ritonavir and cotrimoxazole presenting with ischemic signs in the four limbs. There was acrocyanosis and weak radial and ulnar pulses. A family member referred that the patient used ergot alkaloids for headaches. An ergotism due to the simultaneous use of ergot alkaloids and antiretroviral therapy was suspected. The latter was discontinued and intravenous nitroglycerin, nifedipine and pentoxifyline were started with good results.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.6 20162016-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000600017es10.4067/S0034-98872016000600017 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Acquired Immunodeficiency Syndrome Ergotism Ischemia |
spellingShingle |
Acquired Immunodeficiency Syndrome Ergotism Ischemia Cifuentes M,Daniel Blanco L,Sergio Ramírez F,Camila Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case |
description |
High activity antiretroviral therapy may exacerbate the activity of ergot alkaloids due to an inhibition of cytochrome P450. We report a 57 years old female with AIDS treated with lamivudine, zidovudine, atazanavir, ritonavir and cotrimoxazole presenting with ischemic signs in the four limbs. There was acrocyanosis and weak radial and ulnar pulses. A family member referred that the patient used ergot alkaloids for headaches. An ergotism due to the simultaneous use of ergot alkaloids and antiretroviral therapy was suspected. The latter was discontinued and intravenous nitroglycerin, nifedipine and pentoxifyline were started with good results. |
author |
Cifuentes M,Daniel Blanco L,Sergio Ramírez F,Camila |
author_facet |
Cifuentes M,Daniel Blanco L,Sergio Ramírez F,Camila |
author_sort |
Cifuentes M,Daniel |
title |
Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case |
title_short |
Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case |
title_full |
Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case |
title_fullStr |
Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case |
title_full_unstemmed |
Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case |
title_sort |
ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: report of one case |
publisher |
Sociedad Médica de Santiago |
publishDate |
2016 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000600017 |
work_keys_str_mv |
AT cifuentesmdaniel ergotismoporusosimultaneodeergotaminicoyterapiaantirretroviralreportofonecase AT blancolsergio ergotismoporusosimultaneodeergotaminicoyterapiaantirretroviralreportofonecase AT ramirezfcamila ergotismoporusosimultaneodeergotaminicoyterapiaantirretroviralreportofonecase |
_version_ |
1718436890687832064 |