Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México

Background: Obesity during childhood is a risk factor for developing cardiovascular diseases during adulthood. Aim: To measure insulin and glucose levels and parameters of insulin resistance in obese, overweight and normal weight Mexican children. Material and Methods: Comparative study of 21 obese...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rosas-Sumano,Ana Beatriz, Rodal-Canales,Francisco Javier, Barrientos Pérez,Margarita, Cárdenas-Morales,Beatriz Eugenia, Pérez-Campos Mayoral,Laura, Pérez-Campos,Eduardo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Hyperinsulinism Insulin Resistance Obesity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000800010
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872016000800010
record_format	dspace
spelling	oai:scielo:S0034-988720160008000102016-12-21Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, MéxicoRosas-Sumano,Ana BeatrizRodal-Canales,Francisco JavierBarrientos Pérez,MargaritaCárdenas-Morales,Beatriz EugeniaPérez-Campos Mayoral,LauraPérez-Campos,Eduardo Hyperinsulinism Insulin Resistance Obesity Background: Obesity during childhood is a risk factor for developing cardiovascular diseases during adulthood. Aim: To measure insulin and glucose levels and parameters of insulin resistance in obese, overweight and normal weight Mexican children. Material and Methods: Comparative study of 21 obese children with a body mass index (BMI) over percentile 95, aged 10 ± 1 years (10 males), 14 children aged 10 ± 2 (7 males) with a BMI between percentiles 85 and 94 and 16 children aged 9 ± 2 years (3 males) with a body mass index between percentiles 10 and 84. Body weight, blood pressure and waist circumference were measured and a blood sample was obtained to measure fasting glucose and insulin levels. Homeostasis model of insulin resistance (HOMA) and quantitative insulin sensitivity check index (QUICKI) were calculated. Results: Among obese, overweight and normal weight children, insulin levels were 14.9 (95% CI 10.90-18.99), 7.20 (CI 5.12-9.28) and 4.73 (CI 95% 1.92-7.53) uU/ml, respectively. The figures for HOMA were 3.16 (95% CI 2.20-4.12), 1.49 (95% CI 1.03-1.94) and 0.97 (95% CI 0.35-1.60), respectively. The figures for QUICKI were 0.331 (95% CI 0.319-0.343), 0.371 (95% CI 0.349-0.393) and 0.419 (95% CI 0.391-0.446), respectively. Compared to their normal weight counterparts, the risk of obese children and those with a waist circumference over percentile 90 of having a HOMA over 3.16 was 17 and 10 times higher, respectively. BMI correlated better than waist circumference with insulin levels. Conclusions: Obese children have higher levels of insulin resistance than their normal weight counterparts.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.8 20162016-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000800010es10.4067/S0034-98872016000800010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hyperinsulinism Insulin Resistance Obesity
spellingShingle	Hyperinsulinism Insulin Resistance Obesity Rosas-Sumano,Ana Beatriz Rodal-Canales,Francisco Javier Barrientos Pérez,Margarita Cárdenas-Morales,Beatriz Eugenia Pérez-Campos Mayoral,Laura Pérez-Campos,Eduardo Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México
description	Background: Obesity during childhood is a risk factor for developing cardiovascular diseases during adulthood. Aim: To measure insulin and glucose levels and parameters of insulin resistance in obese, overweight and normal weight Mexican children. Material and Methods: Comparative study of 21 obese children with a body mass index (BMI) over percentile 95, aged 10 ± 1 years (10 males), 14 children aged 10 ± 2 (7 males) with a BMI between percentiles 85 and 94 and 16 children aged 9 ± 2 years (3 males) with a body mass index between percentiles 10 and 84. Body weight, blood pressure and waist circumference were measured and a blood sample was obtained to measure fasting glucose and insulin levels. Homeostasis model of insulin resistance (HOMA) and quantitative insulin sensitivity check index (QUICKI) were calculated. Results: Among obese, overweight and normal weight children, insulin levels were 14.9 (95% CI 10.90-18.99), 7.20 (CI 5.12-9.28) and 4.73 (CI 95% 1.92-7.53) uU/ml, respectively. The figures for HOMA were 3.16 (95% CI 2.20-4.12), 1.49 (95% CI 1.03-1.94) and 0.97 (95% CI 0.35-1.60), respectively. The figures for QUICKI were 0.331 (95% CI 0.319-0.343), 0.371 (95% CI 0.349-0.393) and 0.419 (95% CI 0.391-0.446), respectively. Compared to their normal weight counterparts, the risk of obese children and those with a waist circumference over percentile 90 of having a HOMA over 3.16 was 17 and 10 times higher, respectively. BMI correlated better than waist circumference with insulin levels. Conclusions: Obese children have higher levels of insulin resistance than their normal weight counterparts.
author	Rosas-Sumano,Ana Beatriz Rodal-Canales,Francisco Javier Barrientos Pérez,Margarita Cárdenas-Morales,Beatriz Eugenia Pérez-Campos Mayoral,Laura Pérez-Campos,Eduardo
author_facet	Rosas-Sumano,Ana Beatriz Rodal-Canales,Francisco Javier Barrientos Pérez,Margarita Cárdenas-Morales,Beatriz Eugenia Pérez-Campos Mayoral,Laura Pérez-Campos,Eduardo
author_sort	Rosas-Sumano,Ana Beatriz
title	Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México
title_short	Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México
title_full	Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México
title_fullStr	Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México
title_full_unstemmed	Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México
title_sort	hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de oaxaca, méxico
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000800010
work_keys_str_mv	AT rosassumanoanabeatriz hiperinsulinemiayresistenciainsulinicaenninosdedosescuelaspublicasdeoaxacamexico AT rodalcanalesfranciscojavier hiperinsulinemiayresistenciainsulinicaenninosdedosescuelaspublicasdeoaxacamexico AT barrientosperezmargarita hiperinsulinemiayresistenciainsulinicaenninosdedosescuelaspublicasdeoaxacamexico AT cardenasmoralesbeatrizeugenia hiperinsulinemiayresistenciainsulinicaenninosdedosescuelaspublicasdeoaxacamexico AT perezcamposmayorallaura hiperinsulinemiayresistenciainsulinicaenninosdedosescuelaspublicasdeoaxacamexico AT perezcamposeduardo hiperinsulinemiayresistenciainsulinicaenninosdedosescuelaspublicasdeoaxacamexico
_version_	1718436899293495296

Hiperinsulinemia y resistencia insulínica en niños de dos escuelas públicas de Oaxaca, México

Ejemplares similares