Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano

Liquefied hydrocarbon gas, such as propane is considered safe. However there are reports that voluntary exposure to liquefied gas at least could originate hallucinatory states. We report a 20 years old woman who was found in a coma with extensor muscle hypertonia, brisk tendon reflexes and extensor...

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Autores principales:	Cartier R,Luis, Gallardo V,Andrés
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Gas Poisoning Neurotoxicity Syndromes Propanol
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000800018
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spelling	oai:scielo:S0034-988720160008000182016-12-21Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propanoCartier R,LuisGallardo V,Andrés Gas Poisoning Neurotoxicity Syndromes Propanol Liquefied hydrocarbon gas, such as propane is considered safe. However there are reports that voluntary exposure to liquefied gas at least could originate hallucinatory states. We report a 20 years old woman who was found in a coma with extensor muscle hypertonia, brisk tendon reflexes and extensor plantar (Babinski) responses after being exposed to propane gas. The brain magnetic resonance imaging (MRI) showed lesions in both hippocampi and white matter in the oval center. The patient had a normal oxygen saturation of 98%, a carboxyhemoglobin of 1.6% and a metabolic acidosis with a pH of 7.01 with an anion gap of 16 mEq/l. This pattern suggested that it was a consequence of the intermediary metabolism of isopropanol. The recovery of the patient was slow and four months later she still had lesions on MRI and limitations in her cognitive sphere, memory and executive functions. Thus, liquefied gas exposure can cause a toxic encephalopathy with a persistent damage of the central nervous system.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.8 20162016-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000800018es10.4067/S0034-98872016000800018
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Gas Poisoning Neurotoxicity Syndromes Propanol
spellingShingle	Gas Poisoning Neurotoxicity Syndromes Propanol Cartier R,Luis Gallardo V,Andrés Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano
description	Liquefied hydrocarbon gas, such as propane is considered safe. However there are reports that voluntary exposure to liquefied gas at least could originate hallucinatory states. We report a 20 years old woman who was found in a coma with extensor muscle hypertonia, brisk tendon reflexes and extensor plantar (Babinski) responses after being exposed to propane gas. The brain magnetic resonance imaging (MRI) showed lesions in both hippocampi and white matter in the oval center. The patient had a normal oxygen saturation of 98%, a carboxyhemoglobin of 1.6% and a metabolic acidosis with a pH of 7.01 with an anion gap of 16 mEq/l. This pattern suggested that it was a consequence of the intermediary metabolism of isopropanol. The recovery of the patient was slow and four months later she still had lesions on MRI and limitations in her cognitive sphere, memory and executive functions. Thus, liquefied gas exposure can cause a toxic encephalopathy with a persistent damage of the central nervous system.
author	Cartier R,Luis Gallardo V,Andrés
author_facet	Cartier R,Luis Gallardo V,Andrés
author_sort	Cartier R,Luis
title	Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano
title_short	Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano
title_full	Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano
title_fullStr	Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano
title_full_unstemmed	Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano
title_sort	encefalopatía tóxica por isopropanol: sobre-exposición accidental a gas propano
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000800018
work_keys_str_mv	AT cartierrluis encefalopatiatoxicaporisopropanolsobreexposicionaccidentalagaspropano AT gallardovandres encefalopatiatoxicaporisopropanolsobreexposicionaccidentalagaspropano
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Encefalopatía tóxica por isopropanol: Sobre-exposición accidental a gas propano

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