Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico

Neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, which preferentially attacks the optic nerve and spinal cord. It is associated with antibodies against aquaporin 4. Morbidity and mortality are higher than in multiple sclerosis and its treatment focuses on i...

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Autores principales:	Suárez H,Felipe, Urrutia E,Daniela, Canales P,Felipe, Gutiérrez O,Camila
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Lupus Erythematosus, Systemic Neuromyelitis Optica
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000900020
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spelling	oai:scielo:S0034-988720160009000202016-12-23Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínicoSuárez H,FelipeUrrutia E,DanielaCanales P,FelipeGutiérrez O,Camila Lupus Erythematosus, Systemic Neuromyelitis Optica Neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, which preferentially attacks the optic nerve and spinal cord. It is associated with antibodies against aquaporin 4. Morbidity and mortality are higher than in multiple sclerosis and its treatment focuses on immunosuppressive drugs. Immunomodulators are contraindicated. We report a previously healthy 35-year-old man, presenting with NMO concomitantly with systemic lupus erythematosus. His evolution was torpid with three outbreaks in the 10 months after the diagnosis, requiring a first-line therapy with methylprednisolone and cyclophosphamide and then a second-line therapy with rituximab.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.9 20162016-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000900020es10.4067/S0034-98872016000900020
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Lupus Erythematosus, Systemic Neuromyelitis Optica
spellingShingle	Lupus Erythematosus, Systemic Neuromyelitis Optica Suárez H,Felipe Urrutia E,Daniela Canales P,Felipe Gutiérrez O,Camila Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
description	Neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, which preferentially attacks the optic nerve and spinal cord. It is associated with antibodies against aquaporin 4. Morbidity and mortality are higher than in multiple sclerosis and its treatment focuses on immunosuppressive drugs. Immunomodulators are contraindicated. We report a previously healthy 35-year-old man, presenting with NMO concomitantly with systemic lupus erythematosus. His evolution was torpid with three outbreaks in the 10 months after the diagnosis, requiring a first-line therapy with methylprednisolone and cyclophosphamide and then a second-line therapy with rituximab.
author	Suárez H,Felipe Urrutia E,Daniela Canales P,Felipe Gutiérrez O,Camila
author_facet	Suárez H,Felipe Urrutia E,Daniela Canales P,Felipe Gutiérrez O,Camila
author_sort	Suárez H,Felipe
title	Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
title_short	Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
title_full	Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
title_fullStr	Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
title_full_unstemmed	Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico
title_sort	neuromielitis óptica y lupus eritematoso sistémico en un hombre: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000900020
work_keys_str_mv	AT suarezhfelipe neuromielitisopticaylupuseritematososistemicoenunhombrecasoclinico AT urrutiaedaniela neuromielitisopticaylupuseritematososistemicoenunhombrecasoclinico AT canalespfelipe neuromielitisopticaylupuseritematososistemicoenunhombrecasoclinico AT gutierrezocamila neuromielitisopticaylupuseritematososistemicoenunhombrecasoclinico
_version_	1718436906517135360

Neuromielitis óptica y lupus eritematoso sistémico en un hombre: Caso clínico

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