Síndrome metabólico e inflamación en adultos: Un estudio poblacional

Background: Metabolic syndrome is highly prevalent among adults in Chile and represents a health risk. Aim: To determine the relationship between metabolic syndrome (MetS) and its components, with C reactive protein levels (CRP) as an inflammation marker. Material and Methods: The population studied...

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Autores principales: Bustos,Patricia, Rosas,Bernardita, Román,Pablo, Villagrán,Juan, Amigo,Hugo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2016
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001000001
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spelling oai:scielo:S0034-988720160010000012016-12-28Síndrome metabólico e inflamación en adultos: Un estudio poblacionalBustos,PatriciaRosas,BernarditaRomán,PabloVillagrán,JuanAmigo,Hugo Adult C-Reactive Protein Metabolic Syndrome X Background: Metabolic syndrome is highly prevalent among adults in Chile and represents a health risk. Aim: To determine the relationship between metabolic syndrome (MetS) and its components, with C reactive protein levels (CRP) as an inflammation marker. Material and Methods: The population studied consisted of 736 individuals born in a hospital from Valparaíso Region, aged between 32-38 years at the time of the study. MetS was identified according to the Adult Treatment Panel (ATP) III guidelines and inflammation was measured using ultra-sensitive CRP. This parameter was classified as normal for values from 0 to 3 mg/L, high for values from 3.01 to 10 mg/L and very high for values &gt; 10 mg/L. Results: Median CRP was in the normal range (1.9 mg/L, interquartile range 0.7-5.2) and was higher among women than men (2.2 and 1.4 mg/L respectively, p < 0.01). Twenty seven percent of participants had MetS. One-fourth had high blood glucose values, one-third had high triglyceride levels and 28% had blood pressure values over those established as normal in MetS. Elevated waist circumference (WC) and low HDL cholesterol were found among almost 50% of participants. A relationship between MetS and high CRP was only found among men with an Odds ratio (OR) of 2.04 (95% confidence intervals (CI): 1.11-3.73). The same association was observed for high triglyceride levels with an OR of 2.02 (CI: 1.17-3.49) and high WC with an OR of 3.89 (CI: 2.06-7.36). Among women, the only relationship observed was between abdominal obesity and very high CRP with an OR of 2. 65 (CI: 1.20-5.84). Conclusions: Metabolic syndrome, high triglyceride levels, and abdominal obesity were associated with inflammation only in men.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.10 20162016-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001000001es10.4067/S0034-98872016001000001
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Adult
C-Reactive Protein
Metabolic Syndrome X
spellingShingle Adult
C-Reactive Protein
Metabolic Syndrome X
Bustos,Patricia
Rosas,Bernardita
Román,Pablo
Villagrán,Juan
Amigo,Hugo
Síndrome metabólico e inflamación en adultos: Un estudio poblacional
description Background: Metabolic syndrome is highly prevalent among adults in Chile and represents a health risk. Aim: To determine the relationship between metabolic syndrome (MetS) and its components, with C reactive protein levels (CRP) as an inflammation marker. Material and Methods: The population studied consisted of 736 individuals born in a hospital from Valparaíso Region, aged between 32-38 years at the time of the study. MetS was identified according to the Adult Treatment Panel (ATP) III guidelines and inflammation was measured using ultra-sensitive CRP. This parameter was classified as normal for values from 0 to 3 mg/L, high for values from 3.01 to 10 mg/L and very high for values &gt; 10 mg/L. Results: Median CRP was in the normal range (1.9 mg/L, interquartile range 0.7-5.2) and was higher among women than men (2.2 and 1.4 mg/L respectively, p < 0.01). Twenty seven percent of participants had MetS. One-fourth had high blood glucose values, one-third had high triglyceride levels and 28% had blood pressure values over those established as normal in MetS. Elevated waist circumference (WC) and low HDL cholesterol were found among almost 50% of participants. A relationship between MetS and high CRP was only found among men with an Odds ratio (OR) of 2.04 (95% confidence intervals (CI): 1.11-3.73). The same association was observed for high triglyceride levels with an OR of 2.02 (CI: 1.17-3.49) and high WC with an OR of 3.89 (CI: 2.06-7.36). Among women, the only relationship observed was between abdominal obesity and very high CRP with an OR of 2. 65 (CI: 1.20-5.84). Conclusions: Metabolic syndrome, high triglyceride levels, and abdominal obesity were associated with inflammation only in men.
author Bustos,Patricia
Rosas,Bernardita
Román,Pablo
Villagrán,Juan
Amigo,Hugo
author_facet Bustos,Patricia
Rosas,Bernardita
Román,Pablo
Villagrán,Juan
Amigo,Hugo
author_sort Bustos,Patricia
title Síndrome metabólico e inflamación en adultos: Un estudio poblacional
title_short Síndrome metabólico e inflamación en adultos: Un estudio poblacional
title_full Síndrome metabólico e inflamación en adultos: Un estudio poblacional
title_fullStr Síndrome metabólico e inflamación en adultos: Un estudio poblacional
title_full_unstemmed Síndrome metabólico e inflamación en adultos: Un estudio poblacional
title_sort síndrome metabólico e inflamación en adultos: un estudio poblacional
publisher Sociedad Médica de Santiago
publishDate 2016
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001000001
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AT rosasbernardita sindromemetabolicoeinflamacionenadultosunestudiopoblacional
AT romanpablo sindromemetabolicoeinflamacionenadultosunestudiopoblacional
AT villagranjuan sindromemetabolicoeinflamacionenadultosunestudiopoblacional
AT amigohugo sindromemetabolicoeinflamacionenadultosunestudiopoblacional
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