Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro

Background: The effectiveness of intravenous thrombolysis (IVT) in cerebral ischemia is time dependent. Stroke mimics (SM) are frequent in emergency rooms. The effort to reduce door to needle time, can lead to administer thrombolytics to SM. Aim: To describe the frequency and prognosis of SM treated...

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Autores principales:	Brunser,Alejandro M, Hoppe,Arnold, Muñoz,Paula, Lavados,Pablo M, Illanes,Sergio, Díaz,Violeta, Olavarría,Verónica V
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Stroke Therapeutics Thrombolytic Therapy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001000005
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spelling	oai:scielo:S0034-988720160010000052016-12-28Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centroBrunser,Alejandro MHoppe,ArnoldMuñoz,PaulaLavados,Pablo MIllanes,SergioDíaz,VioletaOlavarría,Verónica V Stroke Therapeutics Thrombolytic Therapy Background: The effectiveness of intravenous thrombolysis (IVT) in cerebral ischemia is time dependent. Stroke mimics (SM) are frequent in emergency rooms. The effort to reduce door to needle time, can lead to administer thrombolytics to SM. Aim: To describe the frequency and prognosis of SM treated with IVT. Material and Methods: Prospective analysis of all patients evaluated in a Chilean private clinic between December 2004 and July 2015 with a suspected acute ischemic stroke (AIS). We calculated the number of SM that were treated with IVT. In these patients, we analyzed the presence of symptomatic cerebral hemorrhage defined as the presence of a neurological deterioration of four points or more on the National Institute of Health Stroke Scale, the presence of extracranial bleeding according to Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries criteria and the patient’s functional status at three months by modified Rankin scale (MRS). Results: We evaluated 1,417 patients with suspected AIS, of which 240 (16.9%) were finally diagnosed as SM. A total of 197 patients were treated with IVT, of these 10 (5%) corresponded to SM. All SM patients treated with thrombolytic drugs were functionally independent at 3 months and showed no bleeding complications. Conclusions: Occasionally SM patients were treated with IVT. This treatment was not associated with bleeding complications and the prognosis of these patients at three months was favorable.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.10 20162016-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001000005es10.4067/S0034-98872016001000005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Stroke Therapeutics Thrombolytic Therapy
spellingShingle	Stroke Therapeutics Thrombolytic Therapy Brunser,Alejandro M Hoppe,Arnold Muñoz,Paula Lavados,Pablo M Illanes,Sergio Díaz,Violeta Olavarría,Verónica V Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
description	Background: The effectiveness of intravenous thrombolysis (IVT) in cerebral ischemia is time dependent. Stroke mimics (SM) are frequent in emergency rooms. The effort to reduce door to needle time, can lead to administer thrombolytics to SM. Aim: To describe the frequency and prognosis of SM treated with IVT. Material and Methods: Prospective analysis of all patients evaluated in a Chilean private clinic between December 2004 and July 2015 with a suspected acute ischemic stroke (AIS). We calculated the number of SM that were treated with IVT. In these patients, we analyzed the presence of symptomatic cerebral hemorrhage defined as the presence of a neurological deterioration of four points or more on the National Institute of Health Stroke Scale, the presence of extracranial bleeding according to Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries criteria and the patient’s functional status at three months by modified Rankin scale (MRS). Results: We evaluated 1,417 patients with suspected AIS, of which 240 (16.9%) were finally diagnosed as SM. A total of 197 patients were treated with IVT, of these 10 (5%) corresponded to SM. All SM patients treated with thrombolytic drugs were functionally independent at 3 months and showed no bleeding complications. Conclusions: Occasionally SM patients were treated with IVT. This treatment was not associated with bleeding complications and the prognosis of these patients at three months was favorable.
author	Brunser,Alejandro M Hoppe,Arnold Muñoz,Paula Lavados,Pablo M Illanes,Sergio Díaz,Violeta Olavarría,Verónica V
author_facet	Brunser,Alejandro M Hoppe,Arnold Muñoz,Paula Lavados,Pablo M Illanes,Sergio Díaz,Violeta Olavarría,Verónica V
author_sort	Brunser,Alejandro M
title	Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
title_short	Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
title_full	Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
title_fullStr	Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
title_full_unstemmed	Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
title_sort	trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001000005
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Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro

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