Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico

Among autoimmune encephalitides, a prevalent group are those associated with antibodies against the N-Methyl-D-aspartate receptor, which present with behavior abnormalities, psychosis, seizures and abnormal movements. A new variant, mediated by antibodies against the GABA-A receptor, was recently d...

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Autores principales:	González R,Pablo, Hudson A,Lorena, Basáez M,Esteban, Miranda C,Marcelo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2016
Materias:	Autoimmune Diseases Encephalitis Receptors, GABA
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001100017
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spelling	oai:scielo:S0034-988720160011000172017-01-25Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínicoGonzález R,PabloHudson A,LorenaBasáez M,EstebanMiranda C,Marcelo Autoimmune Diseases Encephalitis Receptors, GABA Among autoimmune encephalitides, a prevalent group are those associated with antibodies against the N-Methyl-D-aspartate receptor, which present with behavior abnormalities, psychosis, seizures and abnormal movements. A new variant, mediated by antibodies against the GABA-A receptor, was recently described. We report a 66-years-old female with this form of encephalitis whose main manifestation was the presence of severe seizures leading to status epilepticus. The patient had a good response to immunomodulatory therapy with intravenous methylprednisolone, azathioprine and anticonvulsants. The laboratory tests initially detected anti-thyroid peroxidase antibodies which lead to the misdiagnosis of Hashimoto Encephalitis, which was ruled out after the detection of antibodies against GABA-A receptor. No malignancy was detected.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.144 n.11 20162016-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001100017es10.4067/S0034-98872016001100017
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Autoimmune Diseases Encephalitis Receptors, GABA
spellingShingle	Autoimmune Diseases Encephalitis Receptors, GABA González R,Pablo Hudson A,Lorena Basáez M,Esteban Miranda C,Marcelo Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico
description	Among autoimmune encephalitides, a prevalent group are those associated with antibodies against the N-Methyl-D-aspartate receptor, which present with behavior abnormalities, psychosis, seizures and abnormal movements. A new variant, mediated by antibodies against the GABA-A receptor, was recently described. We report a 66-years-old female with this form of encephalitis whose main manifestation was the presence of severe seizures leading to status epilepticus. The patient had a good response to immunomodulatory therapy with intravenous methylprednisolone, azathioprine and anticonvulsants. The laboratory tests initially detected anti-thyroid peroxidase antibodies which lead to the misdiagnosis of Hashimoto Encephalitis, which was ruled out after the detection of antibodies against GABA-A receptor. No malignancy was detected.
author	González R,Pablo Hudson A,Lorena Basáez M,Esteban Miranda C,Marcelo
author_facet	González R,Pablo Hudson A,Lorena Basáez M,Esteban Miranda C,Marcelo
author_sort	González R,Pablo
title	Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico
title_short	Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico
title_full	Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico
title_fullStr	Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico
title_full_unstemmed	Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico
title_sort	encefalitis autoinmune por anticuerpos contra el receptor gaba-a: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016001100017
work_keys_str_mv	AT gonzalezrpablo encefalitisautoinmuneporanticuerposcontraelreceptorgabaacasoclinico AT hudsonalorena encefalitisautoinmuneporanticuerposcontraelreceptorgabaacasoclinico AT basaezmesteban encefalitisautoinmuneporanticuerposcontraelreceptorgabaacasoclinico AT mirandacmarcelo encefalitisautoinmuneporanticuerposcontraelreceptorgabaacasoclinico
_version_	1718436916464975872

Encefalitis autoinmune por anticuerpos contra el receptor GABA-A: Caso clínico

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