Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada

Background: Frailty is a geriatric syndrome characterized by a progressive impairment in the subjects’ ability to respond to environmental stress. Frailty is more commonly found in heart failure (HF) patients than in general population and it is an independent predictor of rehospitalization, emergen...

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Autores principales: Díaz-Toro,Felipe, Nazzal Nazal,Carolina, Verdejo,Hugo, Rossel,VÍctor, Castro,Pablo, Larrea,Ricardo, Concepción,Roberto, Sepúlveda,Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2017
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000200003
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spelling oai:scielo:S0034-988720170002000032017-05-02Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensadaDíaz-Toro,FelipeNazzal Nazal,CarolinaVerdejo,HugoRossel,VÍctorCastro,PabloLarrea,RicardoConcepción,RobertoSepúlveda,Luis Geriatrics Frail Elderly Heart Failure Background: Frailty is a geriatric syndrome characterized by a progressive impairment in the subjects’ ability to respond to environmental stress. Frailty is more commonly found in heart failure (HF) patients than in general population and it is an independent predictor of rehospitalization, emergency room visits and death. Aim: To estimate the prevalence of frailty in patients with decompensated HF admitted to four hospitals in Santiago, Chile. Material and Methods: Cross-sectional study. Subjects aged 60 or older consecutively admitted for decompensated HF to the study centers between August 2014 and March 2015 were included. Frailty was defined as the presence of three or more of the following criteria: unintended weight loss, muscular weakness, depression symptoms (exhaustion), reduced gait speed and low physical activity. Independent variables were tested for association using simple logistic regression. Variables associated with frailty (p < 0.05) were included in a multiple logistic regression model. Results: Seventy-nine subjects were included. The prevalence of frailty was 50.6%. Frail patients were mostly female (52.6%) and older than non-frail subjects (73.7± 7.9 vs 68.2 ± 7.1; p < 0.003). Independent predictors of frailty were age (Odds raio (OR) 1.10; 95% confidence intervals (CI): 1.03-1.17), quality of life measured with the Minnesota Living with Heart Failure Questionnaire (OR 1.07; IC95%: 1.03-1.11), previous hospitalizations (OR 2.56; 95%CI: 1.02-6.43) and number of medications (OR 4.46; 95%CI: 1.11-17.32). Conclusions: The prevalence of frailty in patients admitted to the hospital for decompensated heart failure is high. Age, quality of life, hospitalizations and polypharmacy were factors associated with frailty in this group of participants.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.145 n.2 20172017-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000200003es10.4067/S0034-98872017000200003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Geriatrics
Frail Elderly
Heart Failure
spellingShingle Geriatrics
Frail Elderly
Heart Failure
Díaz-Toro,Felipe
Nazzal Nazal,Carolina
Verdejo,Hugo
Rossel,VÍctor
Castro,Pablo
Larrea,Ricardo
Concepción,Roberto
Sepúlveda,Luis
Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
description Background: Frailty is a geriatric syndrome characterized by a progressive impairment in the subjects’ ability to respond to environmental stress. Frailty is more commonly found in heart failure (HF) patients than in general population and it is an independent predictor of rehospitalization, emergency room visits and death. Aim: To estimate the prevalence of frailty in patients with decompensated HF admitted to four hospitals in Santiago, Chile. Material and Methods: Cross-sectional study. Subjects aged 60 or older consecutively admitted for decompensated HF to the study centers between August 2014 and March 2015 were included. Frailty was defined as the presence of three or more of the following criteria: unintended weight loss, muscular weakness, depression symptoms (exhaustion), reduced gait speed and low physical activity. Independent variables were tested for association using simple logistic regression. Variables associated with frailty (p < 0.05) were included in a multiple logistic regression model. Results: Seventy-nine subjects were included. The prevalence of frailty was 50.6%. Frail patients were mostly female (52.6%) and older than non-frail subjects (73.7± 7.9 vs 68.2 ± 7.1; p < 0.003). Independent predictors of frailty were age (Odds raio (OR) 1.10; 95% confidence intervals (CI): 1.03-1.17), quality of life measured with the Minnesota Living with Heart Failure Questionnaire (OR 1.07; IC95%: 1.03-1.11), previous hospitalizations (OR 2.56; 95%CI: 1.02-6.43) and number of medications (OR 4.46; 95%CI: 1.11-17.32). Conclusions: The prevalence of frailty in patients admitted to the hospital for decompensated heart failure is high. Age, quality of life, hospitalizations and polypharmacy were factors associated with frailty in this group of participants.
author Díaz-Toro,Felipe
Nazzal Nazal,Carolina
Verdejo,Hugo
Rossel,VÍctor
Castro,Pablo
Larrea,Ricardo
Concepción,Roberto
Sepúlveda,Luis
author_facet Díaz-Toro,Felipe
Nazzal Nazal,Carolina
Verdejo,Hugo
Rossel,VÍctor
Castro,Pablo
Larrea,Ricardo
Concepción,Roberto
Sepúlveda,Luis
author_sort Díaz-Toro,Felipe
title Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
title_short Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
title_full Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
title_fullStr Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
title_full_unstemmed Factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
title_sort factores asociados a fragilidad en pacientes hospitalizados con insuficiencia cardiaca descompensada
publisher Sociedad Médica de Santiago
publishDate 2017
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000200003
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