Enfermedad diverticular: mitos y realidades

Diverticulosis and diverticular disease of the colon are common conditions in Western countries. The incidence and prevalence of these diseases are increasing and becoming significant for health systems. A growing body of knowledge is shifting the paradigm of the pathogenesis and treatment of divert...

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Autores principales:	Fluxá,Daniela, Quera,Rodrigo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2017
Materias:	Colonic Diseases Diverticulosis Diverticulitis, Colonic
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000200009
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spelling	oai:scielo:S0034-988720170002000092017-05-02Enfermedad diverticular: mitos y realidadesFluxá,DanielaQuera,Rodrigo Colonic Diseases Diverticulosis Diverticulitis, Colonic Diverticulosis and diverticular disease of the colon are common conditions in Western countries. The incidence and prevalence of these diseases are increasing and becoming significant for health systems. A growing body of knowledge is shifting the paradigm of the pathogenesis and treatment of diverticular disease. Low-grade inflammation, altered intestinal microbiota, visceral hypersensitivity, and abnormal colonic motility have been identified as factors leading to diverticular disease. The risk of developing diverticulitis among individuals with diverticulosis is lower than 10 to 25%. Studies indicate that diverticular disease may become a chronic disorder in some patients, not merely an acute illness. Contrary to the advice from international guidelines, studies have not shown that a high-fiber diet protects against diverticulosis. The evidence about the use of antibiotics in uncomplicated diverticulitis is sparse and of low quality. In relation to surgery, studies support a more conservative approach to prophylactic surgery in patients with recurrent disease or chronic symptoms. Finally, new pathophysiological knowledge suggests that other treatments may be useful (mesalamine, rifaximin and probiotics). However, more research is necessary to validate the safety, effectiveness and cost-effectiveness of these strategies.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.145 n.2 20172017-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000200009es10.4067/S0034-98872017000200009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Colonic Diseases Diverticulosis Diverticulitis, Colonic
spellingShingle	Colonic Diseases Diverticulosis Diverticulitis, Colonic Fluxá,Daniela Quera,Rodrigo Enfermedad diverticular: mitos y realidades
description	Diverticulosis and diverticular disease of the colon are common conditions in Western countries. The incidence and prevalence of these diseases are increasing and becoming significant for health systems. A growing body of knowledge is shifting the paradigm of the pathogenesis and treatment of diverticular disease. Low-grade inflammation, altered intestinal microbiota, visceral hypersensitivity, and abnormal colonic motility have been identified as factors leading to diverticular disease. The risk of developing diverticulitis among individuals with diverticulosis is lower than 10 to 25%. Studies indicate that diverticular disease may become a chronic disorder in some patients, not merely an acute illness. Contrary to the advice from international guidelines, studies have not shown that a high-fiber diet protects against diverticulosis. The evidence about the use of antibiotics in uncomplicated diverticulitis is sparse and of low quality. In relation to surgery, studies support a more conservative approach to prophylactic surgery in patients with recurrent disease or chronic symptoms. Finally, new pathophysiological knowledge suggests that other treatments may be useful (mesalamine, rifaximin and probiotics). However, more research is necessary to validate the safety, effectiveness and cost-effectiveness of these strategies.
author	Fluxá,Daniela Quera,Rodrigo
author_facet	Fluxá,Daniela Quera,Rodrigo
author_sort	Fluxá,Daniela
title	Enfermedad diverticular: mitos y realidades
title_short	Enfermedad diverticular: mitos y realidades
title_full	Enfermedad diverticular: mitos y realidades
title_fullStr	Enfermedad diverticular: mitos y realidades
title_full_unstemmed	Enfermedad diverticular: mitos y realidades
title_sort	enfermedad diverticular: mitos y realidades
publisher	Sociedad Médica de Santiago
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000200009
work_keys_str_mv	AT fluxadaniela enfermedaddiverticularmitosyrealidades AT querarodrigo enfermedaddiverticularmitosyrealidades
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Enfermedad diverticular: mitos y realidades

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