Cólico biliar inducido por morfina

Cólico biliar inducido por morfina

Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consu...

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Autores principales: Berger,Zoltán, Arcos,Mario, Matamala,Fernanda, Rojas,Claudia
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2017
Materias:
Morphine
Sphincter of Oddi
Sphincter of Oddi Dysfunction
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000300018
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spelling oai:scielo:S0034-988720170003000182017-05-18Cólico biliar inducido por morfinaBerger,ZoltánArcos,MarioMatamala,FernandaRojas,Claudia Morphine Sphincter of Oddi Sphincter of Oddi Dysfunction Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epigastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics. Transaminases elevated from previously normal value to over 1,000 U/L, and returned to the normal level without further treatment after several days. Magnetic resonance cholangiography showed normal fine bile duct, without stones. This transient increase in hepatic enzymes was considered as a consequence of high biliary pressure secondary to morphine-induced spastic contraction of Oddi’s sphincter and a consecutive hepatocellular necrosis.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.145 n.3 20172017-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000300018es10.4067/S0034-98872017000300018
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Morphine
Sphincter of Oddi
Sphincter of Oddi Dysfunction
spellingShingle Morphine
Sphincter of Oddi
Sphincter of Oddi Dysfunction
Berger,Zoltán
Arcos,Mario
Matamala,Fernanda
Rojas,Claudia
Cólico biliar inducido por morfina
description Morphine produces contraction of Oddi’s sphincter, which can be severe and of longer duration in some pathological conditions. This exaggerated response can manifest as a colicky biliary pain, frequently accompanied by a dramatic increase in hepatic enzymes. We report a 32 years old female who consulted in the emergency room for severe low abdominal pain of gynecologic origin, which was completely controlled by morphine. However, she presented a sudden epigastric colicky pain irradiating in the back, which persisted for several hours in spite of the repeated administration of analgesics. Transaminases elevated from previously normal value to over 1,000 U/L, and returned to the normal level without further treatment after several days. Magnetic resonance cholangiography showed normal fine bile duct, without stones. This transient increase in hepatic enzymes was considered as a consequence of high biliary pressure secondary to morphine-induced spastic contraction of Oddi’s sphincter and a consecutive hepatocellular necrosis.
author Berger,Zoltán
Arcos,Mario
Matamala,Fernanda
Rojas,Claudia
author_facet Berger,Zoltán
Arcos,Mario
Matamala,Fernanda
Rojas,Claudia
author_sort Berger,Zoltán
title Cólico biliar inducido por morfina
title_short Cólico biliar inducido por morfina
title_full Cólico biliar inducido por morfina
title_fullStr Cólico biliar inducido por morfina
title_full_unstemmed Cólico biliar inducido por morfina
title_sort cólico biliar inducido por morfina
publisher Sociedad Médica de Santiago
publishDate 2017
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000300018
work_keys_str_mv AT bergerzoltan colicobiliarinducidopormorfina
AT arcosmario colicobiliarinducidopormorfina
AT matamalafernanda colicobiliarinducidopormorfina
AT rojasclaudia colicobiliarinducidopormorfina
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