Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso

The differential diagnosis of pulmonary tuberculosis and lymphoma with pulmonary infiltration is very difficult, given their similar clinical characteristics. We report a 59 year old female with weight loss, fever, dyspnea and cough of several months of duration. She had a cavitated mass in lung ima...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Peña,Camila, Soto,Andrés, Villegas,Pablo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2017
Materias:	Diagnosis, Differential Granuloma Non-Hodgkin Lymphoma Polymerase Chain Reaction Tuberculosis, Pulmonary
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000500014
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872017000500014
record_format	dspace
spelling	oai:scielo:S0034-988720170005000142017-11-16Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un casoPeña,CamilaSoto,AndrésVillegas,Pablo Diagnosis, Differential Granuloma Non-Hodgkin Lymphoma Polymerase Chain Reaction Tuberculosis, Pulmonary The differential diagnosis of pulmonary tuberculosis and lymphoma with pulmonary infiltration is very difficult, given their similar clinical characteristics. We report a 59 year old female with weight loss, fever, dyspnea and cough of several months of duration. She had a cavitated mass in lung imaging. A positive conventional PCR lead to the diagnosis of tuberculosis, but she had negative smears and cultures for Mycobacterium tuberculosis. The patient did not respond to treatment and her clinical condition worsened. A peripheral lymph node biopsy confirmed the presence of a diffuse large B cell non-Hodgkin lymphoma. Bone marrow pathology showed non caseating granulomas, again with negative microbiological tests for M. tuberculosis. Findings in the bone marrow were interpreted as a secondary sarcoid reaction to cancer and PCR results as a false positive. The lymphoma was treated, achieving complete remission. This case highlights the importance of the differential diagnosis between these two entities.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.145 n.5 20172017-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000500014es10.4067/S0034-98872017000500014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Diagnosis, Differential Granuloma Non-Hodgkin Lymphoma Polymerase Chain Reaction Tuberculosis, Pulmonary
spellingShingle	Diagnosis, Differential Granuloma Non-Hodgkin Lymphoma Polymerase Chain Reaction Tuberculosis, Pulmonary Peña,Camila Soto,Andrés Villegas,Pablo Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso
description	The differential diagnosis of pulmonary tuberculosis and lymphoma with pulmonary infiltration is very difficult, given their similar clinical characteristics. We report a 59 year old female with weight loss, fever, dyspnea and cough of several months of duration. She had a cavitated mass in lung imaging. A positive conventional PCR lead to the diagnosis of tuberculosis, but she had negative smears and cultures for Mycobacterium tuberculosis. The patient did not respond to treatment and her clinical condition worsened. A peripheral lymph node biopsy confirmed the presence of a diffuse large B cell non-Hodgkin lymphoma. Bone marrow pathology showed non caseating granulomas, again with negative microbiological tests for M. tuberculosis. Findings in the bone marrow were interpreted as a secondary sarcoid reaction to cancer and PCR results as a false positive. The lymphoma was treated, achieving complete remission. This case highlights the importance of the differential diagnosis between these two entities.
author	Peña,Camila Soto,Andrés Villegas,Pablo
author_facet	Peña,Camila Soto,Andrés Villegas,Pablo
author_sort	Peña,Camila
title	Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso
title_short	Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso
title_full	Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso
title_fullStr	Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso
title_full_unstemmed	Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso
title_sort	granulomas pulmonares y en médula ósea: más allá de la tuberculosis. a propósito de un caso
publisher	Sociedad Médica de Santiago
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000500014
work_keys_str_mv	AT penacamila granulomaspulmonaresyenmedulaoseamasalladelatuberculosisapropositodeuncaso AT sotoandres granulomaspulmonaresyenmedulaoseamasalladelatuberculosisapropositodeuncaso AT villegaspablo granulomaspulmonaresyenmedulaoseamasalladelatuberculosisapropositodeuncaso
_version_	1718436945332273152

Granulomas pulmonares y en médula ósea: más allá de la tuberculosis. A propósito de un caso

Ejemplares similares