Esquizofrenia y su asociación con enfermedades médicas crónicas
The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use of antipsychotics,...
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Sociedad Médica de Santiago
2017
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oai:scielo:S0034-988720170008010472017-11-27Esquizofrenia y su asociación con enfermedades médicas crónicasOrellana,GricelRodríguez,MatíasGonzález,NicolásDurán,Eduardo Antipsychotic Agents Metabolic Syndrome X Schizophrenia The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use of antipsychotics, however, evidence has also shown intrinsic susceptibility of schizophrenic patients the development of chronic conditions. This review aims to update knowledge about chronic conditions such as cardiometabolic risk and sleep, bone and kidney disorders related to SCH. These patients have a high prevalence of risk behaviors, including smoking and poor diet. They have a worse metabolic profile than the general population and a greater likelihood of developing metabolic syndrome, diabetes and cardiovascular disease. SCH has also been associated with other chronic diseases such as osteoporosis and chronic kidney disease. The high prevalence of these comorbidities in schizophrenic population is not explained solely by the antipsychotic treatment, therefore intrinsic mechanisms associated to SCH are postulated to be associated with these conditions. This new information requires a change in the multidisciplinary medical approach for the study and management of schizophrenic patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.145 n.8 20172017-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000801047es10.4067/s0034-98872017000801047 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Antipsychotic Agents Metabolic Syndrome X Schizophrenia |
spellingShingle |
Antipsychotic Agents Metabolic Syndrome X Schizophrenia Orellana,Gricel Rodríguez,Matías González,Nicolás Durán,Eduardo Esquizofrenia y su asociación con enfermedades médicas crónicas |
description |
The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use of antipsychotics, however, evidence has also shown intrinsic susceptibility of schizophrenic patients the development of chronic conditions. This review aims to update knowledge about chronic conditions such as cardiometabolic risk and sleep, bone and kidney disorders related to SCH. These patients have a high prevalence of risk behaviors, including smoking and poor diet. They have a worse metabolic profile than the general population and a greater likelihood of developing metabolic syndrome, diabetes and cardiovascular disease. SCH has also been associated with other chronic diseases such as osteoporosis and chronic kidney disease. The high prevalence of these comorbidities in schizophrenic population is not explained solely by the antipsychotic treatment, therefore intrinsic mechanisms associated to SCH are postulated to be associated with these conditions. This new information requires a change in the multidisciplinary medical approach for the study and management of schizophrenic patients. |
author |
Orellana,Gricel Rodríguez,Matías González,Nicolás Durán,Eduardo |
author_facet |
Orellana,Gricel Rodríguez,Matías González,Nicolás Durán,Eduardo |
author_sort |
Orellana,Gricel |
title |
Esquizofrenia y su asociación con enfermedades médicas crónicas |
title_short |
Esquizofrenia y su asociación con enfermedades médicas crónicas |
title_full |
Esquizofrenia y su asociación con enfermedades médicas crónicas |
title_fullStr |
Esquizofrenia y su asociación con enfermedades médicas crónicas |
title_full_unstemmed |
Esquizofrenia y su asociación con enfermedades médicas crónicas |
title_sort |
esquizofrenia y su asociación con enfermedades médicas crónicas |
publisher |
Sociedad Médica de Santiago |
publishDate |
2017 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000801047 |
work_keys_str_mv |
AT orellanagricel esquizofreniaysuasociacionconenfermedadesmedicascronicas AT rodriguezmatias esquizofreniaysuasociacionconenfermedadesmedicascronicas AT gonzaleznicolas esquizofreniaysuasociacionconenfermedadesmedicascronicas AT duraneduardo esquizofreniaysuasociacionconenfermedadesmedicascronicas |
_version_ |
1718436960943472640 |