Acidosis láctica asociada a metformina. Caso clínico

Metformin-associated lactic acidosis is a severe and infrequent adverse event. Early diagnosis is essential to start an early treatment, which often has favorable results. We report a 56 years old non-insulin-requiring type 2 diabetic female who developed a severe metabolic acidosis associated with...

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Autores principales:	Quintana,Felipe, Pezzani,María José, Orozco,Rodrigo, Dreyse,Jorge, Soto,Leonardo, Regueira,Tomás
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2017
Materias:	Acidosis, Lactic Metformin Renal Insufficiency
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000801072
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spelling	oai:scielo:S0034-988720170008010722017-11-27Acidosis láctica asociada a metformina. Caso clínicoQuintana,FelipePezzani,María JoséOrozco,RodrigoDreyse,JorgeSoto,LeonardoRegueira,Tomás Acidosis, Lactic Metformin Renal Insufficiency Metformin-associated lactic acidosis is a severe and infrequent adverse event. Early diagnosis is essential to start an early treatment, which often has favorable results. We report a 56 years old non-insulin-requiring type 2 diabetic female who developed a severe metabolic acidosis associated with metformin in relation to an acute renal failure secondary to infectious diarrhea. Early treatment with bicarbonate and continuous hemofiltration allowed a quick improvement of the patient. Metformin-associated lactic acidosis has an elevated mortality (50-80%) and has a specific and effective treatment. Therefore, the condition must be born in mind.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.145 n.8 20172017-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000801072es10.4067/s0034-98872017000801072
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Acidosis, Lactic Metformin Renal Insufficiency
spellingShingle	Acidosis, Lactic Metformin Renal Insufficiency Quintana,Felipe Pezzani,María José Orozco,Rodrigo Dreyse,Jorge Soto,Leonardo Regueira,Tomás Acidosis láctica asociada a metformina. Caso clínico
description	Metformin-associated lactic acidosis is a severe and infrequent adverse event. Early diagnosis is essential to start an early treatment, which often has favorable results. We report a 56 years old non-insulin-requiring type 2 diabetic female who developed a severe metabolic acidosis associated with metformin in relation to an acute renal failure secondary to infectious diarrhea. Early treatment with bicarbonate and continuous hemofiltration allowed a quick improvement of the patient. Metformin-associated lactic acidosis has an elevated mortality (50-80%) and has a specific and effective treatment. Therefore, the condition must be born in mind.
author	Quintana,Felipe Pezzani,María José Orozco,Rodrigo Dreyse,Jorge Soto,Leonardo Regueira,Tomás
author_facet	Quintana,Felipe Pezzani,María José Orozco,Rodrigo Dreyse,Jorge Soto,Leonardo Regueira,Tomás
author_sort	Quintana,Felipe
title	Acidosis láctica asociada a metformina. Caso clínico
title_short	Acidosis láctica asociada a metformina. Caso clínico
title_full	Acidosis láctica asociada a metformina. Caso clínico
title_fullStr	Acidosis láctica asociada a metformina. Caso clínico
title_full_unstemmed	Acidosis láctica asociada a metformina. Caso clínico
title_sort	acidosis láctica asociada a metformina. caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000801072
work_keys_str_mv	AT quintanafelipe acidosislacticaasociadaametforminacasoclinico AT pezzanimariajose acidosislacticaasociadaametforminacasoclinico AT orozcorodrigo acidosislacticaasociadaametforminacasoclinico AT dreysejorge acidosislacticaasociadaametforminacasoclinico AT sotoleonardo acidosislacticaasociadaametforminacasoclinico AT regueiratomas acidosislacticaasociadaametforminacasoclinico
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Acidosis láctica asociada a metformina. Caso clínico

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