Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia

Background: Kaposi's sarcoma (KS) is a rare tumor that affects mainly immunodeficient and elderly patients. Aim: To describe the features and outcomes of a cohort of patients with different types of KS treated locally with radiotherapy (RT). Patients and Methods: Retrospective review of pati...

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Autores principales:	Vargas,Andrés, Solé,Sebastián
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2018
Materias:	Radiotherapy Sarcoma Kaposi Therapeutics
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000100032
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spelling	oai:scielo:S0034-988720180001000322018-05-11Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapiaVargas,AndrésSolé,Sebastián Radiotherapy Sarcoma Kaposi Therapeutics Background: Kaposi's sarcoma (KS) is a rare tumor that affects mainly immunodeficient and elderly patients. Aim: To describe the features and outcomes of a cohort of patients with different types of KS treated locally with radiotherapy (RT). Patients and Methods: Retrospective review of patients with KS referred to our radiation oncology center for local treatment of symptomatic lesions that did not respond to high activity anti-retroviral therapy or chemotherapy. Results: Between January 1995 and December 2016, 20 patients with a median age of 40 years (18 males) with KS were assessed and treated with RT due to symptomatic lesions. The most common KS type was epidemic in 15 patients, followed by the classic type in three and the iatrogenic variety in two. In patients with non-epidemic varieties, SK was exclusively cutaneous, while visceral involvement was present in 46% of patients with epidemic SK. Complete response was observed in 95% of cases. Skin toxicity caused by RT was mild in all cases. Conclusions: RT may be considered as a reasonable local treatment choice in classic, iatrogenic and epidemic varieties of KS.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.146 n.1 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000100032es10.4067/s0034-98872018000100032
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Radiotherapy Sarcoma Kaposi Therapeutics
spellingShingle	Radiotherapy Sarcoma Kaposi Therapeutics Vargas,Andrés Solé,Sebastián Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
description	Background: Kaposi's sarcoma (KS) is a rare tumor that affects mainly immunodeficient and elderly patients. Aim: To describe the features and outcomes of a cohort of patients with different types of KS treated locally with radiotherapy (RT). Patients and Methods: Retrospective review of patients with KS referred to our radiation oncology center for local treatment of symptomatic lesions that did not respond to high activity anti-retroviral therapy or chemotherapy. Results: Between January 1995 and December 2016, 20 patients with a median age of 40 years (18 males) with KS were assessed and treated with RT due to symptomatic lesions. The most common KS type was epidemic in 15 patients, followed by the classic type in three and the iatrogenic variety in two. In patients with non-epidemic varieties, SK was exclusively cutaneous, while visceral involvement was present in 46% of patients with epidemic SK. Complete response was observed in 95% of cases. Skin toxicity caused by RT was mild in all cases. Conclusions: RT may be considered as a reasonable local treatment choice in classic, iatrogenic and epidemic varieties of KS.
author	Vargas,Andrés Solé,Sebastián
author_facet	Vargas,Andrés Solé,Sebastián
author_sort	Vargas,Andrés
title	Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
title_short	Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
title_full	Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
title_fullStr	Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
title_full_unstemmed	Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
title_sort	sarcoma de kaposi: variedades clínicas y resultados del tratamiento local con radioterapia
publisher	Sociedad Médica de Santiago
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000100032
work_keys_str_mv	AT vargasandres sarcomadekaposivariedadesclinicasyresultadosdeltratamientolocalconradioterapia AT solesebastian sarcomadekaposivariedadesclinicasyresultadosdeltratamientolocalconradioterapia
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Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia

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