Aplasia medular adquirida y embarazo. Caso clínico

Aplastic anemia (AA) or acquired aplastic anemia is an uncommon and potentially fatal disease. It is defined as reduction of at least two peripheral blood series, associated with persistent bone marrow hypocellularity. It's association with pregnancy is even more uncommon, and it may result in...

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Autores principales:	León,Pilar, Lería,Josefina, Cardemil,Daniela, Díaz,Angélica, Hernández,Miguelina, Chubretovic,Magdalena, González,Josefa, Cabrera,María Elena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2018
Materias:	Anemia Aplastic Immunosuppression Pregnancy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000300399
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spelling	oai:scielo:S0034-988720180003003992018-06-20Aplasia medular adquirida y embarazo. Caso clínicoLeón,PilarLería,JosefinaCardemil,DanielaDíaz,AngélicaHernández,MiguelinaChubretovic,MagdalenaGonzález,JosefaCabrera,María Elena Anemia Aplastic Immunosuppression Pregnancy Aplastic anemia (AA) or acquired aplastic anemia is an uncommon and potentially fatal disease. It is defined as reduction of at least two peripheral blood series, associated with persistent bone marrow hypocellularity. It's association with pregnancy is even more uncommon, and it may result in high mortality for the mother and the child. We report an adolescent female with aplastic anemia, which worsened during pregnancy. Her hemoglobin was 5.2 g/dl, her leukocytes were 1,833/ul and her platelets were 19,000/ul. She was initially treated with cyclosporine and horse antithymocyte globulin without hematologic improvement. At 36 weeks of pregnancy methylprednisolone and platelet transfusions were used and a cesarean section was performed. Six month later she continues to require red blood cell and platelet transfusions.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.146 n.3 20182018-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000300399es10.4067/s0034-98872018000300399
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anemia Aplastic Immunosuppression Pregnancy
spellingShingle	Anemia Aplastic Immunosuppression Pregnancy León,Pilar Lería,Josefina Cardemil,Daniela Díaz,Angélica Hernández,Miguelina Chubretovic,Magdalena González,Josefa Cabrera,María Elena Aplasia medular adquirida y embarazo. Caso clínico
description	Aplastic anemia (AA) or acquired aplastic anemia is an uncommon and potentially fatal disease. It is defined as reduction of at least two peripheral blood series, associated with persistent bone marrow hypocellularity. It's association with pregnancy is even more uncommon, and it may result in high mortality for the mother and the child. We report an adolescent female with aplastic anemia, which worsened during pregnancy. Her hemoglobin was 5.2 g/dl, her leukocytes were 1,833/ul and her platelets were 19,000/ul. She was initially treated with cyclosporine and horse antithymocyte globulin without hematologic improvement. At 36 weeks of pregnancy methylprednisolone and platelet transfusions were used and a cesarean section was performed. Six month later she continues to require red blood cell and platelet transfusions.
author	León,Pilar Lería,Josefina Cardemil,Daniela Díaz,Angélica Hernández,Miguelina Chubretovic,Magdalena González,Josefa Cabrera,María Elena
author_facet	León,Pilar Lería,Josefina Cardemil,Daniela Díaz,Angélica Hernández,Miguelina Chubretovic,Magdalena González,Josefa Cabrera,María Elena
author_sort	León,Pilar
title	Aplasia medular adquirida y embarazo. Caso clínico
title_short	Aplasia medular adquirida y embarazo. Caso clínico
title_full	Aplasia medular adquirida y embarazo. Caso clínico
title_fullStr	Aplasia medular adquirida y embarazo. Caso clínico
title_full_unstemmed	Aplasia medular adquirida y embarazo. Caso clínico
title_sort	aplasia medular adquirida y embarazo. caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000300399
work_keys_str_mv	AT leonpilar aplasiamedularadquiridayembarazocasoclinico AT leriajosefina aplasiamedularadquiridayembarazocasoclinico AT cardemildaniela aplasiamedularadquiridayembarazocasoclinico AT diazangelica aplasiamedularadquiridayembarazocasoclinico AT hernandezmiguelina aplasiamedularadquiridayembarazocasoclinico AT chubretovicmagdalena aplasiamedularadquiridayembarazocasoclinico AT gonzalezjosefa aplasiamedularadquiridayembarazocasoclinico AT cabreramariaelena aplasiamedularadquiridayembarazocasoclinico
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Aplasia medular adquirida y embarazo. Caso clínico

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