Disglucemia asociada a fluoroquinolonas: una revisión estructurada

Fluoroquinolone type antimicrobials can cause hypo or hyperglycemia in certain patients. We performed a structured review about this side effect, searching articles published in English or Spanish with full text access in PubMed/Medline. The following MESH terms were used: Hypoglycemia, Hyperglycemi...

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Autores principales:	Granados,Johan, Ceballos,Mauricio, Amariles,Pedro
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2018
Materias:	Hyperglycemia Hypoglycemia Quinolones
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500618
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spelling	oai:scielo:S0034-988720180005006182018-07-26Disglucemia asociada a fluoroquinolonas: una revisión estructuradaGranados,JohanCeballos,MauricioAmariles,Pedro Hyperglycemia Hypoglycemia Quinolones Fluoroquinolone type antimicrobials can cause hypo or hyperglycemia in certain patients. We performed a structured review about this side effect, searching articles published in English or Spanish with full text access in PubMed/Medline. The following MESH terms were used: Hypoglycemia, Hyperglycemia, Quinolones, Ciprofloxacin, Levofloxacin, Moxifloxacin. Additionally, we evaluated the clinical relevance of potential drug interactions, based on the probability of occurrence and the severity of the interaction effect. We obtained 42 publications about the issue; 22 references were selected, where the severity of the interaction in patients with risk factors was evaluated. Patients receiving antidiabetic medications and with risk factors such as advanced age and renal failure may be more likely to have a severe hypoglycemia. In these patients, this drug interaction should be considered clinically relevant since its risk is high or very high.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.146 n.5 20182018-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500618es10.4067/s0034-98872018000500618
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hyperglycemia Hypoglycemia Quinolones
spellingShingle	Hyperglycemia Hypoglycemia Quinolones Granados,Johan Ceballos,Mauricio Amariles,Pedro Disglucemia asociada a fluoroquinolonas: una revisión estructurada
description	Fluoroquinolone type antimicrobials can cause hypo or hyperglycemia in certain patients. We performed a structured review about this side effect, searching articles published in English or Spanish with full text access in PubMed/Medline. The following MESH terms were used: Hypoglycemia, Hyperglycemia, Quinolones, Ciprofloxacin, Levofloxacin, Moxifloxacin. Additionally, we evaluated the clinical relevance of potential drug interactions, based on the probability of occurrence and the severity of the interaction effect. We obtained 42 publications about the issue; 22 references were selected, where the severity of the interaction in patients with risk factors was evaluated. Patients receiving antidiabetic medications and with risk factors such as advanced age and renal failure may be more likely to have a severe hypoglycemia. In these patients, this drug interaction should be considered clinically relevant since its risk is high or very high.
author	Granados,Johan Ceballos,Mauricio Amariles,Pedro
author_facet	Granados,Johan Ceballos,Mauricio Amariles,Pedro
author_sort	Granados,Johan
title	Disglucemia asociada a fluoroquinolonas: una revisión estructurada
title_short	Disglucemia asociada a fluoroquinolonas: una revisión estructurada
title_full	Disglucemia asociada a fluoroquinolonas: una revisión estructurada
title_fullStr	Disglucemia asociada a fluoroquinolonas: una revisión estructurada
title_full_unstemmed	Disglucemia asociada a fluoroquinolonas: una revisión estructurada
title_sort	disglucemia asociada a fluoroquinolonas: una revisión estructurada
publisher	Sociedad Médica de Santiago
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500618
work_keys_str_mv	AT granadosjohan disglucemiaasociadaafluoroquinolonasunarevisionestructurada AT ceballosmauricio disglucemiaasociadaafluoroquinolonasunarevisionestructurada AT amarilespedro disglucemiaasociadaafluoroquinolonasunarevisionestructurada
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Disglucemia asociada a fluoroquinolonas: una revisión estructurada

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