Supraversión de la mirada en intoxicación mortal por bupropión

Upgaze or sustained elevation of the eyes, is an alteration of ocular motility initially described in hypoxic coma. We report a 65-year-old woman admitted with hypotension and alteration of sensorium due to the ingestion of 9.5 g of Bupropion. She presented two seizures of short duration, without ep...

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Autores principales:	Cartier R.,Luis, Romero O.,Cristian, Pérez P.,Gerardo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2018
Materias:	Bupropion Coma Hypoxia Leukoencephalopathies
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500665
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spelling	oai:scielo:S0034-988720180005006652018-07-26Supraversión de la mirada en intoxicación mortal por bupropiónCartier R.,LuisRomero O.,CristianPérez P.,Gerardo Bupropion Coma Hypoxia Leukoencephalopathies Upgaze or sustained elevation of the eyes, is an alteration of ocular motility initially described in hypoxic coma. We report a 65-year-old woman admitted with hypotension and alteration of sensorium due to the ingestion of 9.5 g of Bupropion. She presented two seizures of short duration, without epileptic activity on the EEG. She had a persistent asynchronous myoclonus in extremities, tachycardia and prolonged Q-t. She suffered a cardiac arrest caused by asystole, which recovered quickly in five minutes. At that moment, upgaze appeared, associated with a persistent ocular opening, which persisted for days, but finally disappeared, without remission of coma. A magnetic resonance imaging done at the eighth day, showed hyperintensity of the oval center and corpus callosum which disappeared in a new imaging study done 30 days later, where images of hypoxia in the basal nuclei and cortex appeared. The patient died forty seven days after admission. Up-gaze is an ominous oculomotor alteration linked to an important but incomplete damage in the cerebral cortex, a condition that perverts some sequences of the ocular opening, reversing the Bell phenomenon and producing eyelid retraction.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.146 n.5 20182018-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500665es10.4067/s0034-98872018000500665
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Bupropion Coma Hypoxia Leukoencephalopathies
spellingShingle	Bupropion Coma Hypoxia Leukoencephalopathies Cartier R.,Luis Romero O.,Cristian Pérez P.,Gerardo Supraversión de la mirada en intoxicación mortal por bupropión
description	Upgaze or sustained elevation of the eyes, is an alteration of ocular motility initially described in hypoxic coma. We report a 65-year-old woman admitted with hypotension and alteration of sensorium due to the ingestion of 9.5 g of Bupropion. She presented two seizures of short duration, without epileptic activity on the EEG. She had a persistent asynchronous myoclonus in extremities, tachycardia and prolonged Q-t. She suffered a cardiac arrest caused by asystole, which recovered quickly in five minutes. At that moment, upgaze appeared, associated with a persistent ocular opening, which persisted for days, but finally disappeared, without remission of coma. A magnetic resonance imaging done at the eighth day, showed hyperintensity of the oval center and corpus callosum which disappeared in a new imaging study done 30 days later, where images of hypoxia in the basal nuclei and cortex appeared. The patient died forty seven days after admission. Up-gaze is an ominous oculomotor alteration linked to an important but incomplete damage in the cerebral cortex, a condition that perverts some sequences of the ocular opening, reversing the Bell phenomenon and producing eyelid retraction.
author	Cartier R.,Luis Romero O.,Cristian Pérez P.,Gerardo
author_facet	Cartier R.,Luis Romero O.,Cristian Pérez P.,Gerardo
author_sort	Cartier R.,Luis
title	Supraversión de la mirada en intoxicación mortal por bupropión
title_short	Supraversión de la mirada en intoxicación mortal por bupropión
title_full	Supraversión de la mirada en intoxicación mortal por bupropión
title_fullStr	Supraversión de la mirada en intoxicación mortal por bupropión
title_full_unstemmed	Supraversión de la mirada en intoxicación mortal por bupropión
title_sort	supraversión de la mirada en intoxicación mortal por bupropión
publisher	Sociedad Médica de Santiago
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000500665
work_keys_str_mv	AT cartierrluis supraversiondelamiradaenintoxicacionmortalporbupropion AT romeroocristian supraversiondelamiradaenintoxicacionmortalporbupropion AT perezpgerardo supraversiondelamiradaenintoxicacionmortalporbupropion
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Supraversión de la mirada en intoxicación mortal por bupropión

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