Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos

Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos

If Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal rep...

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Autores principales: Rathkamp,Mario, Tomicic,Vinko, Cornejo,Juan, Cruz,Pablo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2018
Materias:
Catecholamines
Cytokines
Hemadsorption
Shock, Septic
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000600796
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spelling oai:scielo:S0034-988720180006007962018-08-24Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicosRathkamp,MarioTomicic,VinkoCornejo,JuanCruz,Pablo Catecholamines Cytokines Hemadsorption Shock, Septic If Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacement therapy or conventional hemodialysis. We report two diabetic females aged 50 and 58 years, who underwent a total colectomy and amputation of diabetic foot and who developed a SS with high requirements of vasoactive drugs (norepinephrine and adrenaline) to maintain a mean arterial pressure about 60 mmHg. Both were subjected to hemodialysis, connected to a cytokine hemadsorption device. The most important finding was the progressive reduction of vasopressor doses, effect that was observed nine hours after the beginning of the hemadsorption and lasted until its removal at 26 hours. Both patients survived.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.146 n.6 20182018-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000600796es10.4067/s0034-98872018000600796
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Catecholamines
Cytokines
Hemadsorption
Shock, Septic
spellingShingle Catecholamines
Cytokines
Hemadsorption
Shock, Septic
Rathkamp,Mario
Tomicic,Vinko
Cornejo,Juan
Cruz,Pablo
Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
description If Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacement therapy or conventional hemodialysis. We report two diabetic females aged 50 and 58 years, who underwent a total colectomy and amputation of diabetic foot and who developed a SS with high requirements of vasoactive drugs (norepinephrine and adrenaline) to maintain a mean arterial pressure about 60 mmHg. Both were subjected to hemodialysis, connected to a cytokine hemadsorption device. The most important finding was the progressive reduction of vasopressor doses, effect that was observed nine hours after the beginning of the hemadsorption and lasted until its removal at 26 hours. Both patients survived.
author Rathkamp,Mario
Tomicic,Vinko
Cornejo,Juan
Cruz,Pablo
author_facet Rathkamp,Mario
Tomicic,Vinko
Cornejo,Juan
Cruz,Pablo
author_sort Rathkamp,Mario
title Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
title_short Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
title_full Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
title_fullStr Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
title_full_unstemmed Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. Casos clínicos
title_sort adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario. casos clínicos
publisher Sociedad Médica de Santiago
publishDate 2018
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018000600796
work_keys_str_mv AT rathkampmario adsorcionextracorporeadecitoquinaseneltratamientodelshocksepticorefractariocasosclinicos
AT tomicicvinko adsorcionextracorporeadecitoquinaseneltratamientodelshocksepticorefractariocasosclinicos
AT cornejojuan adsorcionextracorporeadecitoquinaseneltratamientodelshocksepticorefractariocasosclinicos
AT cruzpablo adsorcionextracorporeadecitoquinaseneltratamientodelshocksepticorefractariocasosclinicos
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