Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal

Background: Molecular biological techniques allow the identification of more pathogens associated with community-acquired pneumonia (CAP). Aim: To compare clinical and laboratory parameters of patients with CAP caused by different groups of pathogens. Material and Methods: In a prospective study,...

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Autores principales:	Saldias Peñafiel,Fernando, Gassmann Poniachik,Javiera, Canelo López,Alejandro, Díaz Patiño,Orlando
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2018
Materias:	Community-Acquired Infections Diagnosis Microbiology Pneumonia
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018001201371
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spelling	oai:scielo:S0034-988720180012013712019-02-18Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causalSaldias Peñafiel,FernandoGassmann Poniachik,JavieraCanelo López,AlejandroDíaz Patiño,Orlando Community-Acquired Infections Diagnosis Microbiology Pneumonia Background: Molecular biological techniques allow the identification of more pathogens associated with community-acquired pneumonia (CAP). Aim: To compare clinical and laboratory parameters of patients with CAP caused by different groups of pathogens. Material and Methods: In a prospective study, immunocompetent adult patients hospitalized with CAP were tested for the presence of a broad range of possible respiratory pathogens using bacterial cultures, polymerase chain reaction, urinary antigen testing and serology. Results: Pathogens were detected in 367 of 935 patients with CAP (39.2%). Streptococcus pneumoniae (10.7%) and influenza virus (6%) were the most frequently identified bacterial and viral pathogens, respectively. Pneumococcal pneumonia predominated in older adults, with multiple comorbidities, with elevation of inflammatory parameters and hypoxemia, like other bacterial pneumonias. Viral pneumonia predominated in elderly patients with multiple comorbidities, with a shorter hospital length of stay and lower mortality. Pneumonia associated with atypical microorganisms predominated in young adults, smokers, with subacute clinical evolution. Their hospital stays and lethality was similar to other bacterial pneumonias. Viral and classical bacterial pneumonias predominated in high risk pneumonia severity index categories. Although several variables were associated with the detection of a pathogen group, substantial overlap avoided the identification of reliable clinical predictors to distinguish etiologies. Conclusions: The clinical and radiographic characteristics were similar in pulmonary infections caused by classical bacteria, respiratory viruses and atypical microorganisms. Therefore, microbial testing for common respiratory pathogens is still necessary to optimize treatment.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.146 n.12 20182018-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018001201371es10.4067/s0034-98872018001201371
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Community-Acquired Infections Diagnosis Microbiology Pneumonia
spellingShingle	Community-Acquired Infections Diagnosis Microbiology Pneumonia Saldias Peñafiel,Fernando Gassmann Poniachik,Javiera Canelo López,Alejandro Díaz Patiño,Orlando Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
description	Background: Molecular biological techniques allow the identification of more pathogens associated with community-acquired pneumonia (CAP). Aim: To compare clinical and laboratory parameters of patients with CAP caused by different groups of pathogens. Material and Methods: In a prospective study, immunocompetent adult patients hospitalized with CAP were tested for the presence of a broad range of possible respiratory pathogens using bacterial cultures, polymerase chain reaction, urinary antigen testing and serology. Results: Pathogens were detected in 367 of 935 patients with CAP (39.2%). Streptococcus pneumoniae (10.7%) and influenza virus (6%) were the most frequently identified bacterial and viral pathogens, respectively. Pneumococcal pneumonia predominated in older adults, with multiple comorbidities, with elevation of inflammatory parameters and hypoxemia, like other bacterial pneumonias. Viral pneumonia predominated in elderly patients with multiple comorbidities, with a shorter hospital length of stay and lower mortality. Pneumonia associated with atypical microorganisms predominated in young adults, smokers, with subacute clinical evolution. Their hospital stays and lethality was similar to other bacterial pneumonias. Viral and classical bacterial pneumonias predominated in high risk pneumonia severity index categories. Although several variables were associated with the detection of a pathogen group, substantial overlap avoided the identification of reliable clinical predictors to distinguish etiologies. Conclusions: The clinical and radiographic characteristics were similar in pulmonary infections caused by classical bacteria, respiratory viruses and atypical microorganisms. Therefore, microbial testing for common respiratory pathogens is still necessary to optimize treatment.
author	Saldias Peñafiel,Fernando Gassmann Poniachik,Javiera Canelo López,Alejandro Díaz Patiño,Orlando
author_facet	Saldias Peñafiel,Fernando Gassmann Poniachik,Javiera Canelo López,Alejandro Díaz Patiño,Orlando
author_sort	Saldias Peñafiel,Fernando
title	Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
title_short	Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
title_full	Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
title_fullStr	Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
title_full_unstemmed	Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
title_sort	características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal
publisher	Sociedad Médica de Santiago
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872018001201371
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Características clínicas de la neumonía adquirida en la comunidad del adulto inmunocompetente hospitalizado según el agente causal

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