Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case

ABSTRACT Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemodialysis. She re...

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Autores principales:	Fica,Alberto, Cataldo,Pabla, Aceituno,Diana, Villarroel,María Ignacia, Escalona,Arturo
Lenguaje:	English
Publicado:	Sociedad Médica de Santiago 2019
Materias:	Acute Kidney Injury Adenoviridae Adrenal Cortex Hormones Cross Infection Enterocolitis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000200256
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spelling	oai:scielo:S0034-988720190002002562019-04-29Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one caseFica,AlbertoCataldo,PablaAceituno,DianaVillarroel,María IgnaciaEscalona,Arturo Acute Kidney Injury Adenoviridae Adrenal Cortex Hormones Cross Infection Enterocolitis ABSTRACT Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemodialysis. She received high corticosteroid doses due to an initial suspicion of alveolar hemorrhage. Lymphopenia already present before steroid use (567/μL), was maintained during the whole hospital stay (mean 782/μL). From the second week of admission she presented a high-volume diarrhea (mean 2.5 L/day) associated to intermittent bloody stools. An ulcerative enterocolitis was confirmed by CT images and colonoscopy. ADV was detected in a colonic tissue sample by real time PCR but not by a commercial filmarray test. Cidofovir-probenecid and racecadotril therapy were indicated without changing the clinical course of diarrhea and the patient finally died.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.147 n.2 20192019-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000200256en10.4067/s0034-98872019000200256
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Acute Kidney Injury Adenoviridae Adrenal Cortex Hormones Cross Infection Enterocolitis
spellingShingle	Acute Kidney Injury Adenoviridae Adrenal Cortex Hormones Cross Infection Enterocolitis Fica,Alberto Cataldo,Pabla Aceituno,Diana Villarroel,María Ignacia Escalona,Arturo Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
description	ABSTRACT Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemodialysis. She received high corticosteroid doses due to an initial suspicion of alveolar hemorrhage. Lymphopenia already present before steroid use (567/μL), was maintained during the whole hospital stay (mean 782/μL). From the second week of admission she presented a high-volume diarrhea (mean 2.5 L/day) associated to intermittent bloody stools. An ulcerative enterocolitis was confirmed by CT images and colonoscopy. ADV was detected in a colonic tissue sample by real time PCR but not by a commercial filmarray test. Cidofovir-probenecid and racecadotril therapy were indicated without changing the clinical course of diarrhea and the patient finally died.
author	Fica,Alberto Cataldo,Pabla Aceituno,Diana Villarroel,María Ignacia Escalona,Arturo
author_facet	Fica,Alberto Cataldo,Pabla Aceituno,Diana Villarroel,María Ignacia Escalona,Arturo
author_sort	Fica,Alberto
title	Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
title_short	Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
title_full	Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
title_fullStr	Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
title_full_unstemmed	Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
title_sort	fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. report of one case
publisher	Sociedad Médica de Santiago
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000200256
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_version_	1718437049460064256

Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case

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