Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico

Stiff-person syndrome is characterized by persistent muscle spasms, involving agonist and antagonist muscles simultaneously, starting in the lower limbs and trunk. It tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that later become continuous and usually pa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Guajardo,Gonzalo, Cea,Gabriel
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2019
Materias:	Autoimmune Diseases Conversion Disorders Glutamate Decarboxylase Stiff-Person Syndrome
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000600799
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872019000600799
record_format	dspace
spelling	oai:scielo:S0034-988720190006007992019-08-28Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínicoGuajardo,GonzaloCea,Gabriel Autoimmune Diseases Conversion Disorders Glutamate Decarboxylase Stiff-Person Syndrome Stiff-person syndrome is characterized by persistent muscle spasms, involving agonist and antagonist muscles simultaneously, starting in the lower limbs and trunk. It tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that later become continuous and usually painful. Minor sensory stimuli, such as noise or light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. We present a case that for two years was diagnosed and treated as a conversion disorder associated with depression. After two years she was admitted to another hospital with an unmistakable picture of stiff-person syndrome with hypertrophy and rigidity of lower limb muscles, compatible electrophysiology and positive anti-GAD antibodies. She had autoimmune hypothyroidism, that should have raised the suspicion of stiff-person syndrome earlier. She responded to intravenous immunoglobulin and mycophenolate mofetil and and to tranquilizers that have muscle relaxant properties.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.147 n.6 20192019-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000600799es10.4067/S0034-98872019000600799
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Autoimmune Diseases Conversion Disorders Glutamate Decarboxylase Stiff-Person Syndrome
spellingShingle	Autoimmune Diseases Conversion Disorders Glutamate Decarboxylase Stiff-Person Syndrome Guajardo,Gonzalo Cea,Gabriel Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico
description	Stiff-person syndrome is characterized by persistent muscle spasms, involving agonist and antagonist muscles simultaneously, starting in the lower limbs and trunk. It tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that later become continuous and usually painful. Minor sensory stimuli, such as noise or light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. We present a case that for two years was diagnosed and treated as a conversion disorder associated with depression. After two years she was admitted to another hospital with an unmistakable picture of stiff-person syndrome with hypertrophy and rigidity of lower limb muscles, compatible electrophysiology and positive anti-GAD antibodies. She had autoimmune hypothyroidism, that should have raised the suspicion of stiff-person syndrome earlier. She responded to intravenous immunoglobulin and mycophenolate mofetil and and to tranquilizers that have muscle relaxant properties.
author	Guajardo,Gonzalo Cea,Gabriel
author_facet	Guajardo,Gonzalo Cea,Gabriel
author_sort	Guajardo,Gonzalo
title	Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico
title_short	Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico
title_full	Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico
title_fullStr	Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico
title_full_unstemmed	Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico
title_sort	síndrome de persona rígida confundido por trastorno conversivo: un error común. caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000600799
work_keys_str_mv	AT guajardogonzalo sindromedepersonarigidaconfundidoportrastornoconversivounerrorcomuncasoclinico AT ceagabriel sindromedepersonarigidaconfundidoportrastornoconversivounerrorcomuncasoclinico
_version_	1718437069962870784

Síndrome de persona rígida confundido por trastorno conversivo: un error común. Caso clínico

Ejemplares similares