Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico

Pneumococcal meningitis produces several inflammatory disorders in susceptible subjects. A worsening of meningitis can occur on the fourth day of evolution in relation with the withdrawal of steroids. Other complications include the development of inflammatory signs in the post-acute stage of infect...

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Autores principales: Cea,Gabriel, Barria,Silvia, Leiderman,Victoria, Cartier,Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2019
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000600803
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spelling oai:scielo:S0034-988720190006008032019-08-28Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínicoCea,GabrielBarria,SilviaLeiderman,VictoriaCartier,Luis Hydrocephalus Meningitis Meningitis, Pneumococcal Streptococcus pneumoniae Pneumococcal meningitis produces several inflammatory disorders in susceptible subjects. A worsening of meningitis can occur on the fourth day of evolution in relation with the withdrawal of steroids. Other complications include the development of inflammatory signs in the post-acute stage of infection associated with disseminated vasculitis of the cerebral blood vessels and, even later, an autoimmune chronic meningitis. All these inflammatory complications are well controlled with the use of steroids. We report a 53-year-old woman with pneumococcal meningitis that had a good response to treatment with antibiotics and steroids. On the four day, after the steroids were discontinued, she complained of headache, became confused, and had an abnormal cerebrospinal fluid (CSF), report CT angiography showed signs of arteritis. She improved when the steroids were re-started. She was discharged in good condition but after slow tapering of the steroids over a four-month period she had a relapse of all her symptoms and had a gait disturbance. On readmission, she had an inflammatory CSF, there were no signs of infection and the cerebral MRI showed meningeal thickening with ventricular space enlargement. She improved again with steroids and she is now well on high-dose steroids but deteriorates each time the steroids are stopped. She experienced both acute and sub-acute inflammatory responses and finally developed a chronic meningitis responsive, and is dependent on steroids.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.147 n.6 20192019-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000600803es10.4067/S0034-98872019000600803
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Hydrocephalus
Meningitis
Meningitis, Pneumococcal
Streptococcus pneumoniae
spellingShingle Hydrocephalus
Meningitis
Meningitis, Pneumococcal
Streptococcus pneumoniae
Cea,Gabriel
Barria,Silvia
Leiderman,Victoria
Cartier,Luis
Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico
description Pneumococcal meningitis produces several inflammatory disorders in susceptible subjects. A worsening of meningitis can occur on the fourth day of evolution in relation with the withdrawal of steroids. Other complications include the development of inflammatory signs in the post-acute stage of infection associated with disseminated vasculitis of the cerebral blood vessels and, even later, an autoimmune chronic meningitis. All these inflammatory complications are well controlled with the use of steroids. We report a 53-year-old woman with pneumococcal meningitis that had a good response to treatment with antibiotics and steroids. On the four day, after the steroids were discontinued, she complained of headache, became confused, and had an abnormal cerebrospinal fluid (CSF), report CT angiography showed signs of arteritis. She improved when the steroids were re-started. She was discharged in good condition but after slow tapering of the steroids over a four-month period she had a relapse of all her symptoms and had a gait disturbance. On readmission, she had an inflammatory CSF, there were no signs of infection and the cerebral MRI showed meningeal thickening with ventricular space enlargement. She improved again with steroids and she is now well on high-dose steroids but deteriorates each time the steroids are stopped. She experienced both acute and sub-acute inflammatory responses and finally developed a chronic meningitis responsive, and is dependent on steroids.
author Cea,Gabriel
Barria,Silvia
Leiderman,Victoria
Cartier,Luis
author_facet Cea,Gabriel
Barria,Silvia
Leiderman,Victoria
Cartier,Luis
author_sort Cea,Gabriel
title Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico
title_short Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico
title_full Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico
title_fullStr Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico
title_full_unstemmed Meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. Caso clínico
title_sort meningitis crónica autoinmune secundaria a meningitis aguda por neumococo. caso clínico
publisher Sociedad Médica de Santiago
publishDate 2019
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000600803
work_keys_str_mv AT ceagabriel meningitiscronicaautoinmunesecundariaameningitisagudaporneumocococasoclinico
AT barriasilvia meningitiscronicaautoinmunesecundariaameningitisagudaporneumocococasoclinico
AT leidermanvictoria meningitiscronicaautoinmunesecundariaameningitisagudaporneumocococasoclinico
AT cartierluis meningitiscronicaautoinmunesecundariaameningitisagudaporneumocococasoclinico
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