Cuantificación de esteatosis hepática no alcohólica por resonancia magnética

Background: A simple and inexpensive method is required to assess fatty infiltration of the liver non-invasively. Aim: To develop and compare different methods to quantify liver fat by magnetic resonance and compare it against ultrasound. Material and Methods: Three algorithms were implemented: r...

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Autores principales:	Herrera,Rodrigo, Peñaloza,Francisco, Arrieta,Cristóbal, Zacconi,Flavia, Saavedra,Víctor, Saavedra,Carla, Brañes,Cecilia, Hack,Thomas, Uribe,Sergio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2019
Materias:	Fatty Liver Magnetic Resonance Imaging
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000700821
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spelling	oai:scielo:S0034-988720190007008212019-11-04Cuantificación de esteatosis hepática no alcohólica por resonancia magnéticaHerrera,RodrigoPeñaloza,FranciscoArrieta,CristóbalZacconi,FlaviaSaavedra,VíctorSaavedra,CarlaBrañes,CeciliaHack,ThomasUribe,Sergio Fatty Liver Magnetic Resonance Imaging Background: A simple and inexpensive method is required to assess fatty infiltration of the liver non-invasively. Aim: To develop and compare different methods to quantify liver fat by magnetic resonance and compare it against ultrasound. Material and Methods: Three algorithms were implemented: region growing (RG), graph cuts (GC) and hierarchical (HR), all based on the IDEAL method to obtain water and fat images. Using these images, the proton density fat fraction (PDFF) was calculated. The three methods were tested in phantoms with known fat percentages and later on we acquired images from 20 volunteers with an ultrasound diagnosis of fatty liver disease in different stages. For everyone, the PDFF of the nine liver segments was determined. Results: In phantoms, the mean error between the real fat percentage and the value obtained through the three methods was −1,26, −1 and −0,8 for RG, GC and HR, respectively. The hierarchical method was more precise and efficient to obtain PDFF. The results in volunteers revealed that ultrasound showed errors categorizing the severity of hepatic steatosis in more than 50% of volunteers. Conclusions: We developed a tool for magnetic resonance, which allows to quantify fat in the liver. This method is less operator dependent than ultrasound and describes the heterogeneity in the fat distribution along the nine hepatic segments.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.147 n.7 20192019-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000700821es10.4067/S0034-98872019000700821
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Fatty Liver Magnetic Resonance Imaging
spellingShingle	Fatty Liver Magnetic Resonance Imaging Herrera,Rodrigo Peñaloza,Francisco Arrieta,Cristóbal Zacconi,Flavia Saavedra,Víctor Saavedra,Carla Brañes,Cecilia Hack,Thomas Uribe,Sergio Cuantificación de esteatosis hepática no alcohólica por resonancia magnética
description	Background: A simple and inexpensive method is required to assess fatty infiltration of the liver non-invasively. Aim: To develop and compare different methods to quantify liver fat by magnetic resonance and compare it against ultrasound. Material and Methods: Three algorithms were implemented: region growing (RG), graph cuts (GC) and hierarchical (HR), all based on the IDEAL method to obtain water and fat images. Using these images, the proton density fat fraction (PDFF) was calculated. The three methods were tested in phantoms with known fat percentages and later on we acquired images from 20 volunteers with an ultrasound diagnosis of fatty liver disease in different stages. For everyone, the PDFF of the nine liver segments was determined. Results: In phantoms, the mean error between the real fat percentage and the value obtained through the three methods was −1,26, −1 and −0,8 for RG, GC and HR, respectively. The hierarchical method was more precise and efficient to obtain PDFF. The results in volunteers revealed that ultrasound showed errors categorizing the severity of hepatic steatosis in more than 50% of volunteers. Conclusions: We developed a tool for magnetic resonance, which allows to quantify fat in the liver. This method is less operator dependent than ultrasound and describes the heterogeneity in the fat distribution along the nine hepatic segments.
author	Herrera,Rodrigo Peñaloza,Francisco Arrieta,Cristóbal Zacconi,Flavia Saavedra,Víctor Saavedra,Carla Brañes,Cecilia Hack,Thomas Uribe,Sergio
author_facet	Herrera,Rodrigo Peñaloza,Francisco Arrieta,Cristóbal Zacconi,Flavia Saavedra,Víctor Saavedra,Carla Brañes,Cecilia Hack,Thomas Uribe,Sergio
author_sort	Herrera,Rodrigo
title	Cuantificación de esteatosis hepática no alcohólica por resonancia magnética
title_short	Cuantificación de esteatosis hepática no alcohólica por resonancia magnética
title_full	Cuantificación de esteatosis hepática no alcohólica por resonancia magnética
title_fullStr	Cuantificación de esteatosis hepática no alcohólica por resonancia magnética
title_full_unstemmed	Cuantificación de esteatosis hepática no alcohólica por resonancia magnética
title_sort	cuantificación de esteatosis hepática no alcohólica por resonancia magnética
publisher	Sociedad Médica de Santiago
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019000700821
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Cuantificación de esteatosis hepática no alcohólica por resonancia magnética

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