Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K

Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer. Aim: To evaluate the correlation of CoaguChek Pro II™, Xprecia&...

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Autores principales: Roco,Ángela, Nieto,Elena, Quintana,Marianela, Muñoz,Jessica, Ortíz,Víctor, Moreno,Marcelo, Mejías,Fanny, Godoy,Gerald, Zambrano,Johana, Bruna,Stephanie, Bravo,Gabriela, Cabrera,Claudia, Salas,Patricio, Moena,Valeria, Leal,Bryan, Suárez,Marcelo, Quiñones,Luis A.
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2019
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019001001273
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spelling oai:scielo:S0034-988720190010012732020-01-16Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina KRoco,ÁngelaNieto,ElenaQuintana,MarianelaMuñoz,JessicaOrtíz,VíctorMoreno,MarceloMejías,FannyGodoy,GeraldZambrano,JohanaBruna,StephanieBravo,GabrielaCabrera,ClaudiaSalas,PatricioMoena,ValeriaLeal,BryanSuárez,MarceloQuiñones,Luis A. Acenocoumarol Anticoagulants International Normalized Ratio Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer. Aim: To evaluate the correlation of CoaguChek Pro II™, Xprecia™ and microINR™ with venous INR measured at the clinical laboratory and their ease of use. Materials and Methods: Patients provided capillary and venous blood samples for parallel tests comparing Xprecia™ Stride with CoaguChek Pro II™ and with venous INR, microINR™ with CoaguChek Pro IITM and with venous INR. The devices’ ease of use was assessed surveying the sampling staff. Results: The three tested devices had good correlation coefficients with venous INR: CoaguChek Pro IITM 0.953 and 0.962; Xprecia™ of 0.912 and microINR™ of 0.932. The correlation coefficient of Xprecia™ with CoaguChek Pro IITM was 0.937 and microINR™ with CoaguChek Pro IITM was 0.976. Conclusions: CoaguChek Pro IITM, Xprecia™ and microINR™ results had a good correlation coefficient with INR measured at the laboratory. Our results indicate that, in the hands of trained users, POC-type coagulometers are reliable and acceptable for routine use in anticoagulant treatment control.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.147 n.10 20192019-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019001001273es10.4067/s0034-98872019001001273
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Acenocoumarol
Anticoagulants
International Normalized Ratio
spellingShingle Acenocoumarol
Anticoagulants
International Normalized Ratio
Roco,Ángela
Nieto,Elena
Quintana,Marianela
Muñoz,Jessica
Ortíz,Víctor
Moreno,Marcelo
Mejías,Fanny
Godoy,Gerald
Zambrano,Johana
Bruna,Stephanie
Bravo,Gabriela
Cabrera,Claudia
Salas,Patricio
Moena,Valeria
Leal,Bryan
Suárez,Marcelo
Quiñones,Luis A.
Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K
description Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer. Aim: To evaluate the correlation of CoaguChek Pro II™, Xprecia™ and microINR™ with venous INR measured at the clinical laboratory and their ease of use. Materials and Methods: Patients provided capillary and venous blood samples for parallel tests comparing Xprecia™ Stride with CoaguChek Pro II™ and with venous INR, microINR™ with CoaguChek Pro IITM and with venous INR. The devices’ ease of use was assessed surveying the sampling staff. Results: The three tested devices had good correlation coefficients with venous INR: CoaguChek Pro IITM 0.953 and 0.962; Xprecia™ of 0.912 and microINR™ of 0.932. The correlation coefficient of Xprecia™ with CoaguChek Pro IITM was 0.937 and microINR™ with CoaguChek Pro IITM was 0.976. Conclusions: CoaguChek Pro IITM, Xprecia™ and microINR™ results had a good correlation coefficient with INR measured at the laboratory. Our results indicate that, in the hands of trained users, POC-type coagulometers are reliable and acceptable for routine use in anticoagulant treatment control.
author Roco,Ángela
Nieto,Elena
Quintana,Marianela
Muñoz,Jessica
Ortíz,Víctor
Moreno,Marcelo
Mejías,Fanny
Godoy,Gerald
Zambrano,Johana
Bruna,Stephanie
Bravo,Gabriela
Cabrera,Claudia
Salas,Patricio
Moena,Valeria
Leal,Bryan
Suárez,Marcelo
Quiñones,Luis A.
author_facet Roco,Ángela
Nieto,Elena
Quintana,Marianela
Muñoz,Jessica
Ortíz,Víctor
Moreno,Marcelo
Mejías,Fanny
Godoy,Gerald
Zambrano,Johana
Bruna,Stephanie
Bravo,Gabriela
Cabrera,Claudia
Salas,Patricio
Moena,Valeria
Leal,Bryan
Suárez,Marcelo
Quiñones,Luis A.
author_sort Roco,Ángela
title Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K
title_short Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K
title_full Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K
title_fullStr Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K
title_full_unstemmed Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K
title_sort estudio comparativo de equipos inr capilar “point of care” versus inr venoso, en pacientes en tratamiento con antagonistas de vitamina k
publisher Sociedad Médica de Santiago
publishDate 2019
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019001001273
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