Hierro intravenoso en la terapia del síndrome de piernas inquietas

Restless legs syndrome (RLS) may severely affect the quality of life of patients. A deficient iron incorporation into the central nervous system has an important role in the pathophysiology of RLS. Severely affected patients may not respond to current therapeutic options. We report a preliminary exp...

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Autores principales:	MIRANDA C.,MARCELO, BUSTAMANTE C.,M. LEONOR
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2019
Materias:	Iron: Restless Legs Syndrome Therapeutics
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019001201569
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spelling	oai:scielo:S0034-988720190012015692020-07-22Hierro intravenoso en la terapia del síndrome de piernas inquietasMIRANDA C.,MARCELOBUSTAMANTE C.,M. LEONOR Iron: Restless Legs Syndrome Therapeutics Restless legs syndrome (RLS) may severely affect the quality of life of patients. A deficient iron incorporation into the central nervous system has an important role in the pathophysiology of RLS. Severely affected patients may not respond to current therapeutic options. We report a preliminary experience with five patients with severe RLS and low serum ferritin levels who did not improve with oral iron. All were treated with 1 g of intravenous iron carboxymaltose. They experienced a marked improvement in symptoms, evident even during the first week of therapy that had persistent after up to two years of follow-up. A significant change in the RLS severity scale was observed after intravenous iron. Serum ferritin levels increased in all of them. Intravenous iron could be a therapeutic option for patients with severe RLS.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.147 n.12 20192019-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019001201569es10.4067/S0034-98872019001201569
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Iron: Restless Legs Syndrome Therapeutics
spellingShingle	Iron: Restless Legs Syndrome Therapeutics MIRANDA C.,MARCELO BUSTAMANTE C.,M. LEONOR Hierro intravenoso en la terapia del síndrome de piernas inquietas
description	Restless legs syndrome (RLS) may severely affect the quality of life of patients. A deficient iron incorporation into the central nervous system has an important role in the pathophysiology of RLS. Severely affected patients may not respond to current therapeutic options. We report a preliminary experience with five patients with severe RLS and low serum ferritin levels who did not improve with oral iron. All were treated with 1 g of intravenous iron carboxymaltose. They experienced a marked improvement in symptoms, evident even during the first week of therapy that had persistent after up to two years of follow-up. A significant change in the RLS severity scale was observed after intravenous iron. Serum ferritin levels increased in all of them. Intravenous iron could be a therapeutic option for patients with severe RLS.
author	MIRANDA C.,MARCELO BUSTAMANTE C.,M. LEONOR
author_facet	MIRANDA C.,MARCELO BUSTAMANTE C.,M. LEONOR
author_sort	MIRANDA C.,MARCELO
title	Hierro intravenoso en la terapia del síndrome de piernas inquietas
title_short	Hierro intravenoso en la terapia del síndrome de piernas inquietas
title_full	Hierro intravenoso en la terapia del síndrome de piernas inquietas
title_fullStr	Hierro intravenoso en la terapia del síndrome de piernas inquietas
title_full_unstemmed	Hierro intravenoso en la terapia del síndrome de piernas inquietas
title_sort	hierro intravenoso en la terapia del síndrome de piernas inquietas
publisher	Sociedad Médica de Santiago
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872019001201569
work_keys_str_mv	AT mirandacmarcelo hierrointravenosoenlaterapiadelsindromedepiernasinquietas AT bustamantecmleonor hierrointravenosoenlaterapiadelsindromedepiernasinquietas
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Hierro intravenoso en la terapia del síndrome de piernas inquietas

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