Hipofisitis linfocitaria primaria. Caso clínico

Primary lymphocytic hypophysitis is an autoimmune disease characterized by lymphocytic infiltration of the pituitary gland, with a higher incidence during late pregnancy and the postpartum period. It causes glandular destruction, mass effect and symptoms such headache, visual field defects, ophthalm...

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Autores principales:	Reyes S.,Pablo, Andreu,Daniel, Toledo,Camila
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2020
Materias:	Autoimmune Hypophysitis Hypopituitarism Pituitary Gland Postpartum Period
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000200258
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spelling	oai:scielo:S0034-988720200002002582020-06-11Hipofisitis linfocitaria primaria. Caso clínicoReyes S.,PabloAndreu,DanielToledo,Camila Autoimmune Hypophysitis Hypopituitarism Pituitary Gland Postpartum Period Primary lymphocytic hypophysitis is an autoimmune disease characterized by lymphocytic infiltration of the pituitary gland, with a higher incidence during late pregnancy and the postpartum period. It causes glandular destruction, mass effect and symptoms such headache, visual field defects, ophthalmoplegia and symptoms of hypopituitarism. We report a 38-year-old postpartum woman who, after giving birth presented decreased left visual acuity associated with a non ictal headache. Magnetic resonance imaging demonstrated a sellar mass associated with decreased free thyroxine and cortisol levels. Suspecting a primary lymphocytic hypophysitis, she was treated with prednisone 60 mg/day and hormonal replacement therapy. One month later, size of the pituitary gland decreased, and the visual field defect improved. Steroidal treatment was maintained for 36 months and progressively tapered. After two years of follow-up, the imaging studies show a normal sized pituitary gland.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.2 20202020-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000200258es10.4067/s0034-98872020000200258
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Autoimmune Hypophysitis Hypopituitarism Pituitary Gland Postpartum Period
spellingShingle	Autoimmune Hypophysitis Hypopituitarism Pituitary Gland Postpartum Period Reyes S.,Pablo Andreu,Daniel Toledo,Camila Hipofisitis linfocitaria primaria. Caso clínico
description	Primary lymphocytic hypophysitis is an autoimmune disease characterized by lymphocytic infiltration of the pituitary gland, with a higher incidence during late pregnancy and the postpartum period. It causes glandular destruction, mass effect and symptoms such headache, visual field defects, ophthalmoplegia and symptoms of hypopituitarism. We report a 38-year-old postpartum woman who, after giving birth presented decreased left visual acuity associated with a non ictal headache. Magnetic resonance imaging demonstrated a sellar mass associated with decreased free thyroxine and cortisol levels. Suspecting a primary lymphocytic hypophysitis, she was treated with prednisone 60 mg/day and hormonal replacement therapy. One month later, size of the pituitary gland decreased, and the visual field defect improved. Steroidal treatment was maintained for 36 months and progressively tapered. After two years of follow-up, the imaging studies show a normal sized pituitary gland.
author	Reyes S.,Pablo Andreu,Daniel Toledo,Camila
author_facet	Reyes S.,Pablo Andreu,Daniel Toledo,Camila
author_sort	Reyes S.,Pablo
title	Hipofisitis linfocitaria primaria. Caso clínico
title_short	Hipofisitis linfocitaria primaria. Caso clínico
title_full	Hipofisitis linfocitaria primaria. Caso clínico
title_fullStr	Hipofisitis linfocitaria primaria. Caso clínico
title_full_unstemmed	Hipofisitis linfocitaria primaria. Caso clínico
title_sort	hipofisitis linfocitaria primaria. caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000200258
work_keys_str_mv	AT reyesspablo hipofisitislinfocitariaprimariacasoclinico AT andreudaniel hipofisitislinfocitariaprimariacasoclinico AT toledocamila hipofisitislinfocitariaprimariacasoclinico
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Hipofisitis linfocitaria primaria. Caso clínico

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