Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica

Background: The treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is based on corticosteroids, immunoglobulin and plasmapheresis. In our Health System, corticosteroids are commonly used as first line therapy for economic reasons and accessibility. However, the factors as...

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Autores principales:	Fuentealba S.,Mario, Molina D.,Ignacio, Vera-Calzaretta,Aldo, Pérez-Villalobos,Cristhian, Klaassen P.,Gonzalo, Juica A.,Sergio, González-Burboa,Alexis
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2020
Materias:	Corticosteroids Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Therapeutics
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000500594
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spelling	oai:scielo:S0034-988720200005005942020-09-29Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónicaFuentealba S.,MarioMolina D.,IgnacioVera-Calzaretta,AldoPérez-Villalobos,CristhianKlaassen P.,GonzaloJuica A.,SergioGonzález-Burboa,Alexis Corticosteroids Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Therapeutics Background: The treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is based on corticosteroids, immunoglobulin and plasmapheresis. In our Health System, corticosteroids are commonly used as first line therapy for economic reasons and accessibility. However, the factors associated with a good response are not well known. Aim: To assess the association of demographic, clinical and laboratory variables with a favorable response to corticosteroid therapy in patients with CIDP. Material and Methods: Observational, descriptive, longitudinal and retrospective study of 33 patients with a diagnosis of typical, definitive or probable CIDP, treated with corticosteroids for at least six months. Results: Twenty-three patients had a good clinical response to corticosteroid treatment and 10 were non-responders. The variables significantly associated with a good response to steroids were a disease lasting less than 1 year prior to the start of treatment, the absence of axonal damage in electromyography a relapsing-recurrent course and a favorable response within two months of treatment. Conclusions: Most of these patients with CIDP had good response to corticosteroid therapy.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.5 20202020-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000500594es10.4067/S0034-98872020000500594
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Corticosteroids Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Therapeutics
spellingShingle	Corticosteroids Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Therapeutics Fuentealba S.,Mario Molina D.,Ignacio Vera-Calzaretta,Aldo Pérez-Villalobos,Cristhian Klaassen P.,Gonzalo Juica A.,Sergio González-Burboa,Alexis Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
description	Background: The treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is based on corticosteroids, immunoglobulin and plasmapheresis. In our Health System, corticosteroids are commonly used as first line therapy for economic reasons and accessibility. However, the factors associated with a good response are not well known. Aim: To assess the association of demographic, clinical and laboratory variables with a favorable response to corticosteroid therapy in patients with CIDP. Material and Methods: Observational, descriptive, longitudinal and retrospective study of 33 patients with a diagnosis of typical, definitive or probable CIDP, treated with corticosteroids for at least six months. Results: Twenty-three patients had a good clinical response to corticosteroid treatment and 10 were non-responders. The variables significantly associated with a good response to steroids were a disease lasting less than 1 year prior to the start of treatment, the absence of axonal damage in electromyography a relapsing-recurrent course and a favorable response within two months of treatment. Conclusions: Most of these patients with CIDP had good response to corticosteroid therapy.
author	Fuentealba S.,Mario Molina D.,Ignacio Vera-Calzaretta,Aldo Pérez-Villalobos,Cristhian Klaassen P.,Gonzalo Juica A.,Sergio González-Burboa,Alexis
author_facet	Fuentealba S.,Mario Molina D.,Ignacio Vera-Calzaretta,Aldo Pérez-Villalobos,Cristhian Klaassen P.,Gonzalo Juica A.,Sergio González-Burboa,Alexis
author_sort	Fuentealba S.,Mario
title	Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
title_short	Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
title_full	Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
title_fullStr	Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
title_full_unstemmed	Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
title_sort	factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica
publisher	Sociedad Médica de Santiago
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000500594
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Factores asociados a respuesta favorable de tratamiento corticoidal en pacientes con polirradiculoneuropatía desmielinizante inflamatoria crónica

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