Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico

C1q nephropathy is a rare glomerulopathy characterized by mesangial deposition of the complement component C1q. These deposits can be isolated or associated with immunoglobulins or complement fractions, which are observed by immunofluorescence or immunohistochemical microscopy. In ultramicroscopy, d...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Vega,Jorge, Gutiérrez,Elisa, Méndez,Gonzalo P., Bofill,Luis
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2020
Materias:	Complement System Proteins Glomerulonephritis Nephrosis, Lipoid Nephrotic Syndrome Proteinuria
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000500702
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872020000500702
record_format	dspace
spelling	oai:scielo:S0034-988720200005007022020-09-29Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínicoVega,JorgeGutiérrez,ElisaMéndez,Gonzalo P.Bofill,Luis Complement System Proteins Glomerulonephritis Nephrosis, Lipoid Nephrotic Syndrome Proteinuria C1q nephropathy is a rare glomerulopathy characterized by mesangial deposition of the complement component C1q. These deposits can be isolated or associated with immunoglobulins or complement fractions, which are observed by immunofluorescence or immunohistochemical microscopy. In ultramicroscopy, dense mesangial deposits and alterations of the podocyte are observed. Clinically it presents as a nephrotic syndrome (NS) or by alterations of the urinalysis such as proteinuria and/or hematuria in children and young adults. In light microscopy, it is expressed with a morphological pattern of minimal change disease (MCD), mesangial proliferative glomerulonephritis or focal segmental glomerulosclerosis (FSGS). The NS during its evolution usually evolve in steroid resistance or steroid dependency, often requiring the association of immunosuppressants to obtain remission. We report a 14 years old male with a history of NS and its evolution under various treatments during a 12-year follow-up.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.5 20202020-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000500702es10.4067/S0034-98872020000500702
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Complement System Proteins Glomerulonephritis Nephrosis, Lipoid Nephrotic Syndrome Proteinuria
spellingShingle	Complement System Proteins Glomerulonephritis Nephrosis, Lipoid Nephrotic Syndrome Proteinuria Vega,Jorge Gutiérrez,Elisa Méndez,Gonzalo P. Bofill,Luis Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico
description	C1q nephropathy is a rare glomerulopathy characterized by mesangial deposition of the complement component C1q. These deposits can be isolated or associated with immunoglobulins or complement fractions, which are observed by immunofluorescence or immunohistochemical microscopy. In ultramicroscopy, dense mesangial deposits and alterations of the podocyte are observed. Clinically it presents as a nephrotic syndrome (NS) or by alterations of the urinalysis such as proteinuria and/or hematuria in children and young adults. In light microscopy, it is expressed with a morphological pattern of minimal change disease (MCD), mesangial proliferative glomerulonephritis or focal segmental glomerulosclerosis (FSGS). The NS during its evolution usually evolve in steroid resistance or steroid dependency, often requiring the association of immunosuppressants to obtain remission. We report a 14 years old male with a history of NS and its evolution under various treatments during a 12-year follow-up.
author	Vega,Jorge Gutiérrez,Elisa Méndez,Gonzalo P. Bofill,Luis
author_facet	Vega,Jorge Gutiérrez,Elisa Méndez,Gonzalo P. Bofill,Luis
author_sort	Vega,Jorge
title	Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico
title_short	Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico
title_full	Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico
title_fullStr	Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico
title_full_unstemmed	Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico
title_sort	nefropatía por c1q: una rara variedad de síndrome nefrótico. caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000500702
work_keys_str_mv	AT vegajorge nefropatiaporc1qunararavariedaddesindromenefroticocasoclinico AT gutierrezelisa nefropatiaporc1qunararavariedaddesindromenefroticocasoclinico AT mendezgonzalop nefropatiaporc1qunararavariedaddesindromenefroticocasoclinico AT bofillluis nefropatiaporc1qunararavariedaddesindromenefroticocasoclinico
_version_	1718437128976728064

Nefropatía por C1q: una rara variedad de síndrome nefrótico. Caso clínico

Ejemplares similares