Nueva fórmula para estimar creatininuria en población chilena

Background: Evaluation of 24-hour collection accuracy is based on urinary creatinine excretion (UCr), usually using wide ranges indexed by weight. Equations that predict the expected UCr are also available. Aim: To generate an equation for estimating UCr in Chilean population and evaluate its perf...

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Autores principales:	Huidobro Espinosa,Juan Pablo, Sepúlveda,Rodrigo Andrés, Muñoz,Gonzalo Mauricio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2020
Materias:	Creatinine Glomerular Filtration Rate Kidney Function Tests Renal Elimination
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600734
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spelling	oai:scielo:S0034-988720200006007342020-09-29Nueva fórmula para estimar creatininuria en población chilenaHuidobro Espinosa,Juan PabloSepúlveda,Rodrigo AndrésMuñoz,Gonzalo Mauricio Creatinine Glomerular Filtration Rate Kidney Function Tests Renal Elimination Background: Evaluation of 24-hour collection accuracy is based on urinary creatinine excretion (UCr), usually using wide ranges indexed by weight. Equations that predict the expected UCr are also available. Aim: To generate an equation for estimating UCr in Chilean population and evaluate its performance in comparison to existing formulas. Material and Methods: A total of 464 24-hour urine collections from outpatients aged between 15 and 88 years old were used. Ninety percent of collections (n = 418) were randomly extracted to assess the association between absolute UCr values with sex, age, height and weight of participants. A formula was created to estimate the 24-hour UCr using a multiple linear regression model. In the remaining 10% of urine collections (n = 46), the performance of this formula and others reported in the literature were tested. Results: Age, sex and weight were significantly associated with 24-hour UCr values. The new equation was able to predict UCr values with a similar accuracy than CKD-EPI and Walser equations and outperformed other equations. Conclusions: Our equation developed with Chilean values predicts 24-hour UCr values accurately.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.6 20202020-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600734es10.4067/S0034-98872020000600734
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Creatinine Glomerular Filtration Rate Kidney Function Tests Renal Elimination
spellingShingle	Creatinine Glomerular Filtration Rate Kidney Function Tests Renal Elimination Huidobro Espinosa,Juan Pablo Sepúlveda,Rodrigo Andrés Muñoz,Gonzalo Mauricio Nueva fórmula para estimar creatininuria en población chilena
description	Background: Evaluation of 24-hour collection accuracy is based on urinary creatinine excretion (UCr), usually using wide ranges indexed by weight. Equations that predict the expected UCr are also available. Aim: To generate an equation for estimating UCr in Chilean population and evaluate its performance in comparison to existing formulas. Material and Methods: A total of 464 24-hour urine collections from outpatients aged between 15 and 88 years old were used. Ninety percent of collections (n = 418) were randomly extracted to assess the association between absolute UCr values with sex, age, height and weight of participants. A formula was created to estimate the 24-hour UCr using a multiple linear regression model. In the remaining 10% of urine collections (n = 46), the performance of this formula and others reported in the literature were tested. Results: Age, sex and weight were significantly associated with 24-hour UCr values. The new equation was able to predict UCr values with a similar accuracy than CKD-EPI and Walser equations and outperformed other equations. Conclusions: Our equation developed with Chilean values predicts 24-hour UCr values accurately.
author	Huidobro Espinosa,Juan Pablo Sepúlveda,Rodrigo Andrés Muñoz,Gonzalo Mauricio
author_facet	Huidobro Espinosa,Juan Pablo Sepúlveda,Rodrigo Andrés Muñoz,Gonzalo Mauricio
author_sort	Huidobro Espinosa,Juan Pablo
title	Nueva fórmula para estimar creatininuria en población chilena
title_short	Nueva fórmula para estimar creatininuria en población chilena
title_full	Nueva fórmula para estimar creatininuria en población chilena
title_fullStr	Nueva fórmula para estimar creatininuria en población chilena
title_full_unstemmed	Nueva fórmula para estimar creatininuria en población chilena
title_sort	nueva fórmula para estimar creatininuria en población chilena
publisher	Sociedad Médica de Santiago
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600734
work_keys_str_mv	AT huidobroespinosajuanpablo nuevaformulaparaestimarcreatininuriaenpoblacionchilena AT sepulvedarodrigoandres nuevaformulaparaestimarcreatininuriaenpoblacionchilena AT munozgonzalomauricio nuevaformulaparaestimarcreatininuriaenpoblacionchilena
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Nueva fórmula para estimar creatininuria en población chilena

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