Esofagitis eosinofílica: diagnóstico y manejo

Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease, induced by food allergens, clinically characterized by symptoms of esophageal dysfunction. Pathologically there is a predominant eosinophilic inflammation. This disease is relatively new, and its definitions have evolved over time...

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Autores principales: Ballart,María Jesús, Monrroy,Hugo, Iruretagoyena,Mirentxu, Parada,Alejandra, Torres,Javiera, Espino,Alberto
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2020
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600831
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spelling oai:scielo:S0034-988720200006008312020-09-29Esofagitis eosinofílica: diagnóstico y manejoBallart,María JesúsMonrroy,HugoIruretagoyena,MirentxuParada,AlejandraTorres,JavieraEspino,Alberto Eosinophilic Esophagitis Food Hypersensitivity Gastroesophageal Reflux Proton Pump Inhibitors Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease, induced by food allergens, clinically characterized by symptoms of esophageal dysfunction. Pathologically there is a predominant eosinophilic inflammation. This disease is relatively new, and its definitions have evolved over time. Its prevalence and incidence are increasing and causes clinical problems both in children and adults. Its symptoms include food impaction, dysphagia, symptoms that resemble gastroesophageal reflux, abdominal pain, and vomiting. It can also have extra-digestive symptoms such as rhinosinusitis, chronic cough, recurrent croup and hoarseness. EoE can be associated with other atopic conditions, such as asthma, eczema and food allergies. The diagnosis is made by the analysis of endoscopic biopsies (> 15 eosinophils per high power field). Proton pump inhibitors (PPIs) are currently accepted as a treatment for EoE. The clinical and pathological improvement with the use PPIs ceased to be a criterion to define Esophageal eosinophilia responsive to PPIs as a differential diagnosis, since this condition is currently considered within the EoE spectrum. There are three main treatment approaches for EoE: diet, drugs and dilation. Its diagnosis and early treatment are key to avoid or delay its complications, such as stenosis and severe esophageal dysfunction.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.6 20202020-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600831es10.4067/S0034-98872020000600831
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Eosinophilic Esophagitis
Food Hypersensitivity
Gastroesophageal Reflux
Proton Pump Inhibitors
spellingShingle Eosinophilic Esophagitis
Food Hypersensitivity
Gastroesophageal Reflux
Proton Pump Inhibitors
Ballart,María Jesús
Monrroy,Hugo
Iruretagoyena,Mirentxu
Parada,Alejandra
Torres,Javiera
Espino,Alberto
Esofagitis eosinofílica: diagnóstico y manejo
description Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease, induced by food allergens, clinically characterized by symptoms of esophageal dysfunction. Pathologically there is a predominant eosinophilic inflammation. This disease is relatively new, and its definitions have evolved over time. Its prevalence and incidence are increasing and causes clinical problems both in children and adults. Its symptoms include food impaction, dysphagia, symptoms that resemble gastroesophageal reflux, abdominal pain, and vomiting. It can also have extra-digestive symptoms such as rhinosinusitis, chronic cough, recurrent croup and hoarseness. EoE can be associated with other atopic conditions, such as asthma, eczema and food allergies. The diagnosis is made by the analysis of endoscopic biopsies (> 15 eosinophils per high power field). Proton pump inhibitors (PPIs) are currently accepted as a treatment for EoE. The clinical and pathological improvement with the use PPIs ceased to be a criterion to define Esophageal eosinophilia responsive to PPIs as a differential diagnosis, since this condition is currently considered within the EoE spectrum. There are three main treatment approaches for EoE: diet, drugs and dilation. Its diagnosis and early treatment are key to avoid or delay its complications, such as stenosis and severe esophageal dysfunction.
author Ballart,María Jesús
Monrroy,Hugo
Iruretagoyena,Mirentxu
Parada,Alejandra
Torres,Javiera
Espino,Alberto
author_facet Ballart,María Jesús
Monrroy,Hugo
Iruretagoyena,Mirentxu
Parada,Alejandra
Torres,Javiera
Espino,Alberto
author_sort Ballart,María Jesús
title Esofagitis eosinofílica: diagnóstico y manejo
title_short Esofagitis eosinofílica: diagnóstico y manejo
title_full Esofagitis eosinofílica: diagnóstico y manejo
title_fullStr Esofagitis eosinofílica: diagnóstico y manejo
title_full_unstemmed Esofagitis eosinofílica: diagnóstico y manejo
title_sort esofagitis eosinofílica: diagnóstico y manejo
publisher Sociedad Médica de Santiago
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600831
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